Eureka AIR delivers breakthrough ideas for toughest innovation challenges, trusted by R&D personnel around the world.

Preparation method of 1-amino-2-propanol

A technology of propanol and amino, which is applied in the field of preparation of 1-amino-2-propanol, can solve the problem that the crude product has many by-products and cannot meet the technical requirements and yield of high-purity 1-amino-2-propanol Low-level problems, to achieve the effect of shortening the molecular diffusion time, reducing the thickness of the boundary layer, and improving mass transfer

Inactive Publication Date: 2018-12-07
NANJING HONGBAOLI POLYURETHANE
View PDF13 Cites 5 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The crude product produced by this method has many by-products, and the yield is low. It only contains 85-93% (wt) of 1-amino-2-propanol, and the others are 1,1'-iminodi-2- Propanol and 1,1',1"-nitrilotri-2-propanol by-products cannot meet the process requirements for the preparation of high-purity 1-amino-2-propanol

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0018] Propylene oxide and ammonia water with a concentration of 95wt% are input into the mixer with a metering pump at a molar ratio of 1:1.0, and the temperature in the mixer is controlled at 0°C and the pressure at 3.0MPa; the mixed solution is continuously fed into the microchannel for reaction In the reactor, the material reacts in the channel of the reaction section of the reactor. The temperature is 60°C and the pressure is 3.0MPa. The time is 2S, and the specific cooling rate is controlled at about 1800-2000°C / min. Then the low boilers were removed through a stripping tower to obtain the product 1-amino-2-propanol with a content of 99.2%. In this embodiment, the microchannel reactor is specifically made of stainless steel, wherein the inner diameter of the microchannel is 0.05 mm, and the length of the microchannel is 0.8 m.

Embodiment 2

[0020] Propylene oxide and ammonia water with a concentration of 95wt% are input into the mixer with a metering pump at a molar ratio of 1:1.05, and the temperature in the mixer is controlled to be 10°C and the pressure is 5.0MPa; the mixed solution is continuously passed into the microchannel for reaction In the reactor, the material reacts in the channel of the reaction section of the reactor at a temperature of 80°C and a pressure of 5.0MPa. After staying for 0.5S, the material enters the cooling section of the microchannel reactor and rapidly cools down to terminate the reaction. The outlet temperature is -5°C. The residence time is 3.0S, and the specific cooling rate is controlled at about 1600-1800°C / min. Then the low boilers are removed through a stripping tower to obtain the product 1-amino-2-propanol with a content of 99.0%. The microchannel reactor is specifically made of titanium alloy. The inner diameter of the microchannel is 0.10mm, and the length of the microch...

Embodiment 3

[0022] Propylene oxide and ammonia water with a concentration of 97wt% are input into the mixer with a metering pump at a molar ratio of 1:1.05, respectively, and the temperature in the mixer is controlled at -10°C and the pressure is 8.0MPa; the mixed solution is continuously passed into the microchannel In the reactor, the material reacts in the channel of the reaction section of the reactor at a temperature of 70°C and a pressure of 8.0MPa. After staying for 1.0S, it enters the cooling section of the microchannel reactor and rapidly cools down to terminate the reaction. The outlet temperature is 20°C. The residence time is 2.0S, and the specific cooling rate is controlled at about 1400-1500°C / min. Then the low boilers are removed through a stripping tower to obtain the product 1-amino-2-propanol with a content of 99.6%. The microchannel reactor is specifically made of Hastelloy alloy. The inner diameter of the microchannel is 0.3mm, and the length of the microchannel is 3m...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

PropertyMeasurementUnit
lengthaaaaaaaaaa
Login to View More

Abstract

The invention discloses a preparation method of 1-amino-2-propanol. The preparation method comprises following steps: (1) introducing epoxy propane and ammonia water into a mixer according to a set ratio to form a mixed solution after materials collide at a high speed in the mixer; and (2) introducing the mixed solution into a micro-channel reactor, carrying out reactions in the reaction section of the micro-channel reactor, then cooling the mixed solution in the cooling second of the micro-channel reactor to stop reactions, and removing the low-boiling-point substances in a degassing tower toobtain the product. The adopted micro-channel reactor has an extremely small reaction channel and a greatly large specific surface area (>=20000 m2 / m3); the thickness of the boundary layer is reducedeffectively, the molecule diffusion time is greatly reduced, the mass transfer and heat transfer efficiency is improved, instant mixing and instant reaction are realized, and the reaction efficiencyis greatly improved. The micro-channel reactor is taken as a cooling facility, the materials can be rapidly cooled, the reactions can be stopped instantly, the side reactions are maximally reduced, and the product purity is guaranteed.

Description

technical field [0001] The invention relates to a preparation method of 1-amino-2-propanol, which belongs to the field of organic synthesis. Background technique [0002] 1-Amino-2-propanol (MIPA) is an important fine chemical raw material with a wide range of uses. It is commonly used as surfactants, metal processing fluids, paint coatings, textile printing and dyeing, personal care products, water treatment agents, pharmaceutical and pesticide intermediates One of the raw materials for body and so on. The traditional industrial production method of 1-amino-2-propanol is to add ammonia, propylene oxide and catalyst to the high-pressure reactor for reaction, remove small molecules through deamination and dehydration treatment, and then separate step by step through rectification 1 -Amino-2-propanol, 1,1'-iminodi-2-propanol, 1,1',1"-nitrilotri-2-propanol three products, the process of rectification and separation is complicated , the energy cost is high, and the product is ...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): C07C213/04C07C215/08B01J19/00
CPCB01J19/0093C07C213/04C07C215/08
Inventor 黄东平邢益辉芮辉辉赵德喜范春元
Owner NANJING HONGBAOLI POLYURETHANE
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com