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Hand washing liquid, preparation method and applications thereof

A technology of hand sanitizer and water-soluble matrix, applied in the field of hand sanitizer, can solve the problems of hand-foot-and-mouth disease-free hand-washing products, etc., and achieve the effects of maintaining skin moisture, good wettability, and reducing dry and cracked skin.

Inactive Publication Date: 2018-08-24
TIANJIN INT JOINT ACADEMY OF BIOTECH & MEDICINE
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

There are many disinfectant and antibacterial hand sanitizers on the market today, but there are no hand sanitizers specifically for hand, foot and mouth disease

Method used

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  • Hand washing liquid, preparation method and applications thereof
  • Hand washing liquid, preparation method and applications thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] Embodiment 1: the preparation of hand sanitizer

[0023] Preparation:

[0024] Add 1g of sodium carboxymethylcellulose to 65ml of deionized water, heat and stir until fully swollen, add 30ml of surfactant APG1200 while stirring, then add 3ml of glycerin, 2ml of propylene glycol, and 0.1ml of essence, and mix well.

[0025] By the preparation method of the liquid hand sanitizer of the present embodiment, it can be known that the composition of the liquid hand sanitizer of the present embodiment is as follows:

[0026] Water-soluble base (sodium carboxymethylcellulose): 1%, surfactant APG1200: 30%, glycerin: 3%, propylene glycol: 2%, essence: 0.1%.

[0027] The pH value of the hand sanitizer was measured at 9.

Embodiment 2

[0028] Embodiment 2: The effective detection method and the result of the hand-foot-mouth disease-causing virus inhibited by the hand sanitizer:

[0029] 1. Culture of RD cells

[0030] Thaw the RD cells frozen in liquid nitrogen (gifted by the laboratory of the School of Life Sciences, Tsinghua University) in a 37°C water bath and add them to a culture bottle filled with 20ml of medium. The medium composition is DMEM (Dulbecco's modified eaglemedium)+ 10% fetal bovine serum (Fetal Bovine Serum, FBS) + 1% penicillin and streptomycin (Penicillin-Streptomycin, PS), 37 ° C, 5% CO 2 nourish.

[0031] 2. Amplification of EV71 virus

[0032] When the cells grow to 90% fullness, add EV71 virus (a gift from the laboratory of Tsinghua University School of Life Sciences, the species, acquisition method, experimental method and preservation method of EV71 virus are the same as the patent CN104744433A whose publication date is July 1, 2015 consistent) 200 μL, 37°C, 5% CO 2 nourish. A...

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PUM

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Abstract

The invention discloses a hand washing liquid, a preparation method and applications thereof, wherein the pH value of the hand washing liquid is increased by increasing the amount of an alkaline surfactant so as to inhibit the virus of hand-foot-and-mouth disease, wherein the hand washing liquid comprises, by weight, 0.5-3% of a water-soluble matrix, 5-50% of an alkaline surfactant, 1-4% of glycerin, 1-3% of propylene glycol, 0.1-1% of essence, and the balance of deionized water. According to the present invention, the hand washing liquid can significantly inhibit the virus of hand-foot-and-mouth disease, meets the requirement of the hand washing liquid on the pH value, and further has characteristics of simple production and significant effect.

Description

technical field [0001] The present invention relates to a kind of hand sanitizer, more particularly, relate to a kind of hand sanitizer and its preparation method and application. Background technique [0002] Human hand-foot-mouth disease (HFMD) is an acute infectious disease caused by a variety of enteroviruses, among which enterovirus 71 (EV 71) is the most common in my country. Hand, foot and mouth disease is distributed all over the world, and its incidence has been on the rise in recent years. It can be sporadic or epidemic. The onset season is mostly in summer. The incidence rate is highest in children under five years old, and older children and adults can also be infected. Fever symptoms appear at the onset of the disease, scattered herpes appear on the oral mucosa, maculopapules and herpes appear on the hands, feet and buttocks, and there may be inflammatory flushes around the herpes, and there is less fluid in the pustules. Accompanied by cough, runny nose, loss ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K8/73A61K8/34A61Q19/10A61Q17/00A61P31/14A61K8/60A61K8/86A61K8/41A61K8/36A61K8/46
CPCA61Q17/005A61Q19/10A61K8/345A61K8/361A61K8/41A61K8/463A61K8/602A61K8/731A61K8/86A61K2800/596
Inventor 饶子和杨诚郭宇刘祥王淑艳马海秋毛永红汪颖李玉彩张玉普张金敏
Owner TIANJIN INT JOINT ACADEMY OF BIOTECH & MEDICINE
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