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Zr-based biomedical alloy and preparation method thereof

A biomedical and alloy technology, which is applied in the field of Zr-based biomedical alloys and its preparation, can solve the problems of unfavorable bone healing, stress shielding effect, and affecting the quality of nuclear magnetic resonance images, so as to facilitate healing, alleviate the influence of stress shielding, The effect of reducing the artifact area

Active Publication Date: 2018-06-26
CENT SOUTH UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

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Problems solved by technology

Although β-Ti alloy has a lower elastic modulus, most of them are still higher than the modulus range of human bones (10-30GPa), which is easy to cause stress shielding effect and is not conducive to bone healing
In addition, with the continuous development of medical detection technology, especially the rapid development of nuclear magnetic resonance technology, higher performance requirements are put forward for implant materials. Although Ti is a paramagnetic material with relatively low magnetic properties, there are still many reports It is mentioned that titanium alloy implants can affect the quality of MRI images and form artifact areas

Method used

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  • Zr-based biomedical alloy and preparation method thereof
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  • Zr-based biomedical alloy and preparation method thereof

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Embodiment 1

[0037] A Zr-based biomedical alloy with low modulus and low magnetic susceptibility of the present invention is composed of Nb: 16% by weight, and the balance is zirconium and unavoidable impurity elements.

[0038] The Zr-based biomedical alloy of the present embodiment is prepared by the following method:

[0039] (1) Weigh the raw materials, and weigh the corresponding Zr grains and Nb grains according to the weight percentages of the designed raw material components. The purity of Zr grains and Nb grains are all above 99.99wt%, and the particle size should be kept as consistent as possible.

[0040] (2) Mix the weighed raw materials evenly.

[0041](3) Smelting raw materials: Wipe the inside of the non-consumable vacuum smelting furnace clean to keep the furnace clean, then put the raw materials in step (2) into the copper crucible of the non-consumable vacuum smelting furnace, start vacuuming, and the vacuum degree controlled at 3×10 -3 Pa, argon gas was introduced to r...

Embodiment 2

[0046] A Zr-based biomedical alloy with low modulus and low magnetic susceptibility of the present invention is composed of: Nb: 16%, Ti: 4%, and the balance is zirconium and unavoidable impurity elements.

[0047] The Zr-based biomedical alloy of the present embodiment is prepared by the following method:

[0048] (1) Weigh the raw materials, weigh the corresponding Zr grains, Nb grains, and Ti grains respectively according to the weight percentage of each raw material component designed, and the purity of Zr grains, Nb grains, and Ti grains are all above 99.99wt%, and keep the The particle size is consistent.

[0049] (2) Mix the weighed raw materials evenly.

[0050] (3) Smelting raw materials: Wipe the inside of the non-consumable vacuum smelting furnace clean to keep the furnace clean, then put the raw materials in step (2) into the copper crucible of the non-consumable vacuum smelting furnace, start vacuuming, and the vacuum degree controlled at 3×10 -3 Pa, argon gas ...

Embodiment 3

[0055] A Zr-based biomedical alloy with low modulus and low magnetic susceptibility of the present invention is composed of Nb: 16%, Ti: 8%, and the balance is zirconium and unavoidable impurity elements.

[0056] The Zr-based biomedical alloy of the present embodiment is prepared by the following method:

[0057] (1) Weigh the raw materials, weigh the corresponding Zr grains, Nb grains, and Ti grains respectively according to the weight percentage of each raw material component designed, and the purity of Zr grains, Nb grains, and Ti grains are all above 99.99wt%, and keep the The particle size is consistent.

[0058] (2) Mix the weighed raw materials evenly.

[0059] (3) Smelting raw materials: Wipe the inside of the non-consumable vacuum smelting furnace clean to keep the furnace clean, then put the raw materials in step (2) into the copper crucible of the non-consumable vacuum smelting furnace, start vacuuming, and the vacuum degree controlled at 3×10 -3 Pa, argon gas w...

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Abstract

The invention discloses a Zr-based biomedical alloy and a preparation method thereof. The Zr-based biomedical alloy comprises, by weight, 10.5-19% of niobium, 0%-30% of titanium and the balance zirconium and inevitable impurity elements. The preparation method comprises the following steps that (1) the raw materials are weighed according to the proportion and then are fed into a reaction containerof a vacuum smelting furnace for mixing, and vacuum smelting is carried out on the mixture repeatedly under the shielding of inert gas to obtain molten reaction liquid; and (2) cold water is continuously injected to the bottom of the reaction container to make the molten reaction liquid be cooled rapidly until the temperature is reduced to room temperature, and then the Zr-based biological medical alloy is obtained. According to the Zr-based biomedical alloy, the advantages of low modulus, low magnetic susceptibility, excellent mechanical property and the like are realized, so that the problem of stress shielding possibly caused by metal of an implant is solved, reduction of the magnetic susceptibility of metal-based biological implant materials is facilitated, and the influence on MRI (nuclear magnetic resonance imaging) artifacts is reduced.

Description

technical field [0001] The invention belongs to the technical field of metal-based composite materials, and in particular relates to a Zr-based biomedical alloy and a preparation method thereof. Background technique [0002] Biomedical materials are functional materials used for clinical diagnosis, treatment, repair or replacement of human tissues or organs or enhancement of their functions. Biomedical materials are related to human organs and medical devices. At present, many scholars around the world are conducting in-depth research on them. Biomedical materials have become an indispensable part of the field of material research. General requirements for biomedical materials: (1) must comply with the relevant standards, and should be non-toxic, non-pyrogenic, non-teratogenic, non-carcinogenic, non-allergic, non-interfering with the immune mechanism of the body, and have good blood Compatibility and tissue compatibility, etc. (2) Good biological stability. For biomedical...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): C22C16/00C22C1/02
CPCC22C1/02C22C16/00
Inventor 刘立斌薛人豪章立钢
Owner CENT SOUTH UNIV
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