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Conformal radiotherapy tissue equivalent compensation glue and its preparation method and application

A tissue-equivalent and conformal technology, applied in the field of medical supplies, can solve the problems of easy formation of cavities, affecting the radiation effect of radiotherapy, etc., and achieve the effect of easy steps, reduction of secondary construction effects, and good fit.

Active Publication Date: 2020-12-15
WUXI NO 4 PEOPLES HOSPITAL
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] The purpose of the present invention is to solve the problem that cavities are easily formed during the use of existing tissue equivalent compensators and affect the radiation effect of radiotherapy, and to provide a conformal radiotherapy tissue equivalent compensation glue and its preparation method and application

Method used

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  • Conformal radiotherapy tissue equivalent compensation glue and its preparation method and application
  • Conformal radiotherapy tissue equivalent compensation glue and its preparation method and application

Examples

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Embodiment 1

[0028] A conformal radiotherapy tissue equivalent compensation glue, comprising an uncured layer and a cured layer, the outer layers of the uncured layer and the cured layer are wrapped with a protective layer, the thickness of the cured layer is 3mm, and the thickness of the uncured layer is 0.1mm, The protective layer is made of medical PVC material, and the thickness of the protective layer is 0.2mm. The uncured layer and the cured layer are made of the same raw material components. The raw material components of the uncured layer and the cured layer are calculated in parts by weight: liquid 70 parts of rubber, 12 parts of epoxy soybean oil acrylate, 3 parts of ethoxy ethoxy ethyl acrylate, 0.2 parts of bis 2,6-difluoro-3-pyrrole phenyl titanocene.

[0029] A method for preparing conformal radiotherapy tissue equivalent compensation glue: comprising the following steps:

[0030] (1) First take 70 parts of liquid rubber by weight in the dark state, and add 3 parts of ethoxy ...

Embodiment 2

[0035] A conformal radiotherapy tissue equivalent compensation glue, including an uncured layer and a cured layer, the outer layer of the uncured layer and the cured layer is wrapped with a protective layer, the thickness of the cured layer is 10mm, and the thickness of the uncured layer is x-xmm , the protective layer is made of medical PVC material, the thickness of the protective layer is 0.5mm, the uncured layer and the cured layer are made of the same raw material components, and the raw material components of the uncured layer and the cured layer are calculated in parts by weight: 85 parts of liquid rubber, 10.5 parts of epoxy soybean oil acrylate, 4.5 parts of ethoxy ethoxy ethyl acrylate, 0.5 parts of bis-2,6-difluoro-3-pyrrole phenyl titanocene.

[0036] A method for preparing conformal radiotherapy tissue equivalent compensation glue: comprising the following steps:

[0037] (1) First take 85 parts of liquid rubber by weight in a dark state, and then add 4.5 parts of...

Embodiment 3

[0042] A conformal radiotherapy tissue equivalent compensation glue, including an uncured layer and a cured layer, the outer layer of the uncured layer and the cured layer is wrapped with a protective layer, the thickness of the cured layer is 15mm, and the thickness of the uncured layer is 20mm. The layer is made of medical PVC material, and the thickness of the protective layer is 0.2mm. The uncured layer and the cured layer are made of the same raw material components. The raw material components of the uncured layer and the cured layer are calculated in parts by weight: liquid rubber 90 parts, 8 parts of epoxy soybean oil acrylate, 5 parts of ethoxyethoxyethyl acrylate, 0.8 parts of bis-2,6-difluoro-3-pyrrole phenyl titanocene.

[0043] A method for preparing conformal radiotherapy tissue equivalent compensation glue: comprising the following steps:

[0044] (1) First take 90 parts of liquid rubber by weight in the dark state, and then add 5 parts of ethoxy ethoxy ethyl ac...

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Abstract

The invention relates to a conformal radiotherapy tissue equivalent compensation adhesive, a preparation method and application thereof. The conformal radiotherapy tissue equivalent compensation adhesive comprises an uncured layer and a cured layer, wherein the outer layers of the uncured layer and the cured layer are wrapped with protective layers, and the uncured layer and the cured layer are prepared from same raw material components. The uncured layer and the cured layer are prepared from, by weight, 70-90 parts of liquid rubber, 8-12 parts of epoxy soybean oil acrylate, 3-5 parts of 2(2-ethoxyethoxy) ethylacrylate and 0.2-0.8 part of bis(2,6-difluoro-3-(1-hydropyrrol-1-yl)phenyl)titanocene. The preparation method is simple, and application steps are easy to operate. The tissue equivalent compensation adhesive prepared by using the liquid rubber and the epoxy soybean oil acrylate as the raw materials is soft and comfortable, has a good degree of skin attachment to a patient, can effectively prevent cavity generation and reduce the secondary build-up effect of high-energy rays, can be formed according to conditions of an irradiation site of the patient, has high repeatability precision, and can ensure the accuracy of absorbing dose amount of tissues and reduce radiation reactions.

Description

technical field [0001] The invention relates to a conformal radiotherapy tissue equivalent compensation glue and a preparation method and application thereof, belonging to the technical field of medical supplies. Background technique [0002] Radiation therapy, as one of the three main means of treating malignant tumors, has now entered the era of "three precisions" of precise positioning, precise planning, and precise treatment. From the beginning of considering the preparation of radiotherapy to the end of radiotherapy, every step should Strive for accuracy, mainly including the accuracy of position accuracy and the accuracy of absorbed dose of irradiated tissue. [0003] Radiation therapy external radiation mainly adopts high-energy X-rays and high-energy electron rays. When these high-energy rays enter the human body, there is a dose built-up area. Because the dose curve before the dose built-up area has a large slope and is related to the energy of the rays, even high-e...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61L27/16
CPCA61L27/16A61L27/165
Inventor 杨波
Owner WUXI NO 4 PEOPLES HOSPITAL
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