Traditional Chinese medicine composition as well as preparation method and application thereof

Abstract

The invention provides a traditional Chinese medicine composition for treating ulcerative colitis, peptic ulcers, intestinal fistula and non-healing or chronic wounds. The active component of the traditional Chinese medicine composition is prepared from an extractive A and ganoderma spore powder extractive, wherein the extractive A is prepared by decocting and extracting the following medicinal materials in parts by weight with water: 2-12 parts of herba patriniae, 12-36 parts of semen coicis, 6-18 parts of cortex phellodendri, 6-18 parts of rhizoma corydalis, 6-18 parts of herba taraxaci, 6-18 parts of fructus toosendan and 1-9 parts of licorice roots; and in parts by weight, the amount of the ganoderma spore powder extractive is 0.5-10 parts. The composition provided by the invention provides an effective therapeutic drug for clinically treating refractory diseases including the ulcerative colitis, the intestinal fistula and the non-healing wounds, is economical and practical and has a wide clinic application prospect; and a preparation process of the composition is simple and efficient and is liable to operate and can be used for preparing granules and powder which are convenient to carry, take and locally and externally apply.

Description

technical field [0001] The invention relates to the technical field of medicine, in particular to a traditional Chinese medicine composition for treating ulcerative colitis, peptic ulcer, intestinal fistula, and non-healing or refractory wounds, its preparation method and application. Background technique [0002] 1. Ulcerative colitis (UC) is a chronic non-specific inflammation that mainly involves the rectum and colonic mucosa, and belongs to the category of inflammatory bowel disease. Ulcerative colitis is characterized by chronicity, persistence, recurrent attacks, and the possibility of canceration. Because of its unknown etiology, difficult to cure, and easy to relapse, the World Health Organization classifies it as a difficult disease. [0003] At present, the western medicine treatment drugs for UC are: ①Aminosalicylic acid preparation, which is the current first-line drug, but sulfasalazine has obvious side effects; Clinical long-term use, the curative effect of c...

AI Technical Summary

Problems solved by technology

[0003] At present, the western medicine treatment drugs for UC are: ①Aminosalicylic acid preparation, which is the current first-line drug, but sulfasalazine has obvious side effects; Long-term clinical use, the curative effect of controlling recurrence is not satisfactory

②Glucocorticoids: mainly hydrocortisone succinate, prednisolone, methylprednisolone, etc., which are prone to drug dependence, have obvious side effects, and are difficult to use for a long time

③ Immunosuppressants: mainly cyclosporine, azathioprine, and 6-mercaptopurine, which have obvious toxic and side effects, and are only used in cases where the above-mentioned treatments are ineffective, and the curative effect is uncertain

It is worth noting that excessive use of bitter cold not only hinders the health of the spleen and stomach, but also has the disadvantages of cooling heat, poisoning and reducing dryness and hurting yin.

At the same time, the active stage of ulcerative colitis is mainly characterized by damp heat and blood stasis, and attention should be paid to the treatment of clearing the intestines to remove dampness, cooling blood and stopping bleeding. Currently, there is no compound drug with the best drug ratio in clinical practice, and it cannot be popularized and applied.

[0005] 2. Current treatment status of intestinal fistula

[0009] At present, physiological saline is used clinically to wash the wound, intestinal cavity, and abdominal cavity. Drugs that promote fistula healing

[0010] 3. Current status of treatment of difficult-to-heal wounds

(6) Traditional Chinese medicine treatment, there are many prescriptions at present, and the treatment effect is different

[0022] Although the effect of drug treatment for peptic ulcer has been greatly improved at present, there are still many patients who are not treated well with drugs and develop refractory ulcers, causing serious complications

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