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Probiotic fermented Chinese herbal medicine composition capable of preventing and controlling diabetes

A technology for fermenting Chinese herbal medicines and Chinese herbal medicine extracts, which can be used in drug combinations, metabolic diseases, pharmaceutical formulations, etc., can solve problems such as non-occurrence, and achieve the effects of preventing diabetes, improving intestinal immunity, and improving diabetes.

Inactive Publication Date: 2017-09-15
江苏佰澳达生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] However, there is no composition of Chinese herbal medicine fermented by probiotics on the market, which is specially used to treat or prevent or regulate diabetes

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0023] The preparation method of the probiotic fermented Chinese herbal medicine freeze-dried composition is: will be selected from Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus casei, Lactobacillus reuteri, Lactobacillus acidophilus, Bifidobacterium lactis, Bifidobacterium longum One or more of Bifidobacterium breve, Bifidobacterium bifidum, and Bifidobacterium bifidum are fermented, centrifuged and freeze-dried to obtain a high-activity probiotic freeze-dried powder composition. The preparation of the probiotic freeze-dried powder is carried out according to the operation of the existing probiotic freeze-dried powder. The combination of probiotics includes any proportion of Lactobacillus plantarum, Lactobacillus rhamnosus, Lactobacillus casei; Lactobacillus reuteri, Lactobacillus acidophilus, Bifidobacterium lactis, Lactobacillus rhamnosus; Lactobacillus rhamnosus, Lactobacillus casei, Bifidobacterium breve, Bifidobacterium bifidum.

[0024] Inoculated wit...

Embodiment 1

[0028] The composition of probiotic Chinese herbal medicine for preventing and controlling diabetes mainly includes the following components by mass: 100 parts of probiotic fermented Chinese herbal medicine freeze-dried composition, 50 parts of probiotic exopolysaccharide freeze-dried powder composition, 50 parts of Chinese herbal medicine extract, Chitooligosaccharide 8 parts, fructooligosaccharide 8 parts, inulin 10 parts, soluble dietary fiber 10 parts, insoluble dietary fiber 10 parts. The composition of probiotic Chinese herbal medicine for preventing and controlling diabetes can be obtained by uniformly mixing the aforementioned raw materials.

Embodiment 2

[0030] The composition of probiotic Chinese herbal medicine for preventing and controlling diabetes mainly includes the following components by mass: 100 parts of probiotic fermented Chinese herbal medicine freeze-dried composition, 60 parts of probiotic exopolysaccharide freeze-dried powder composition, 06 parts of Chinese herbal medicine extract, Chitooligosaccharide 6 parts, fructooligosaccharide 6 parts, inulin 10 parts, soluble dietary fiber 10 parts, insoluble dietary fiber 10 parts. The composition of probiotic Chinese herbal medicine for preventing and controlling diabetes can be obtained by uniformly mixing the aforementioned raw materials.

[0031] The probiotic Chinese herbal medicine composition of the present application adopts an environmentally friendly, healthy, and additive-free process in terms of raw material selection and method preparation, which ensures the safety of the composition.

[0032] The first group of 20 healthy people and the second group of 5 ...

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Abstract

The invention relates to a probiotic fermented Chinese herbal medicine composition capable of preventing and controlling diabetes. The probiotic fermented Chinese herbal medicine composition capable of preventing and controlling diabetes mainly comprises following components, by mass, 100 parts of a probiotic fermented Chinese herbal medicine freeze-dried composition, 1 to 100 parts of a probiotic exopolysaccharide freeze-dried composition, 1 to 100 parts of a Chinese herbal medicine extract, 1 to 10 part of chitosan oligosaccharide , 1 to 10 parts of fructo-oligosaccharide, 1 to 10 parts of inulin, 1 to 10 parts of soluble dietary fiber, and 1 to 10 parts of insoluble dietary fiber. According to a preparation method, the above components are mixed to be uniform so as to obtain the probiotic fermented Chinese herbal medicine composition. The probiotic fermented Chinese herbal medicine composition is capable of preventing diabetes, and controlling and improving diabetes symptoms via changing intestinal flora, promoting intestinal activity, and improving immunity. Qualitative and quantitative representation of the change of in vivo immune factors can be realized via measuring related immune factor and endotoxin levels.

Description

technical field [0001] The invention relates to a Chinese herbal medicinal composition fermented by probiotics, in particular to an oral composition capable of effectively preventing and controlling diabetes. Background technique [0002] The pathogenesis of diabetes is directly related to the excessive increase of endotoxin level after intestinal microbial imbalance. Typical opportunistic pathogens include Enterobacter cloacae, Pseudomonas aeruginosa, and sulfate-reducing bacteria of the Enterobacteriaceae family. When there is a problem with the immune system, these opportunistic pathogens will cause a series of symptoms such as the intestinal tract. It leads to the increase of LPS (lipopolysaccharide) of Gram-negative bacteria, induces collective chronic inflammation, and further induces the risk of a series of chronic diseases such as obesity, three highs, and diabetes. [0003] By taking probiotics and Chinese herbal medicines with intestinal microbial targets, the pr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8969A61P3/10A61P1/00A61K35/744A61K35/745A61K35/747A61K31/715
CPCA61K31/715A61K35/744A61K35/745A61K35/747A61K36/07A61K36/074A61K36/185A61K36/284A61K36/42A61K36/481A61K36/539A61K36/57A61K36/605A61K36/70A61K36/718A61K36/734A61K36/79A61K36/8945A61K36/8969A61K2236/19A61K2300/00
Inventor 马凯
Owner 江苏佰澳达生物科技有限公司
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