Monepantel oral solution as well as preparation method and application thereof

A technology of Taier oral liquid and oral liquid, applied in the field of anti-parasitic, can solve the problems of limited vaccine prevention technology, and achieve the effects of difficult drug cross-resistance, small side effects, and rapid absorption

Inactive Publication Date: 2017-06-13
FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

At present, the vaccine prevention technology for most parasitic diseases is very limited, and the main means of prevention and control of animal parasitic diseases are chemical drugs

Method used

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  • Monepantel oral solution as well as preparation method and application thereof
  • Monepantel oral solution as well as preparation method and application thereof
  • Monepantel oral solution as well as preparation method and application thereof

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preparation example Construction

[0057] Simultaneously, the present invention also provides the preparation method of described fenvalerate oil insecticide for aquatic products, and described method comprises the steps:

[0058] Dissolve the monepal, drug sustained-release agent, surfactant, sweetener, and antioxidant in the solvent medium in order according to the prescription dosage, stir to make the drug dissolve completely, quantify the solvent medium, and finally roving filter, pack, and sterilize. Bacteria to obtain Monepal Oral Liquid.

[0059] Furthermore, the present invention also provides the application of the fenvalerate oil insecticide for aquatic products in killing insects on the surface of aquatic products for treating parasitic nematodes in the gastrointestinal tract of cattle and sheep.

Embodiment 1

[0061] Monetaire: 1.0,

[0062] Polyvinylpyrrolidone-15: 1.0%,

[0063] Polysorbate-80: 5%,

[0064] Sodium saccharin: 0.1%,

[0065] Beta-carotene: 0.1%,

[0066] Ethanol: water solution = 3:7: make up.

Embodiment 2

[0068] Monatel: 10%,

[0069] Macrogol 200: 10%,

[0070] Macrogol 15 hydroxystearate: 10%,

[0071] Sucrose: 0.3%,

[0072] Sodium bisulfite: 0.2%,

[0073] Polyoxyethylated castor oil: propylene glycol and water = 2:3:5: make up.

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Abstract

The invention provides a monepantel oral solution, which is applicable to both the treatment and the control of nematodes in gastrointestinal tracts of a cow and a sheep, and is particularly quite applicable to the prevention and the treatment for a milk cow. The monepantel oral solution provided by the invention is convenient to use, and can be directly drunk after being diluted according to a proportion. The monepantel oral solution provided by the invention is high in bioavailability and high in parasite expelling effect; medication times can be reduced; thus, the medication cost is decreased. The synergistic effect is obvious; moreover, the monepantel oral solution can be used for expelling and killing parasites of the nematodes, worms and the likes at the same time; therefore, a preparation of the monepantel oral solution is high in practicability, convenient to medicate, and has quite great market potential and competitiveness. The invention also provides a preparation method and application of the monepantel oral solution.

Description

technical field [0001] The invention relates to the field of anti-parasites, in particular to monepal oral liquid and its preparation method and application. Background technique [0002] The prevention and control of cattle and sheep nematodes and ectoparasites is a worldwide problem. Cattle and sheep nematodes occur widely in Australia, New Zealand, the western United States and Ireland every year, and also occur frequently in Xinjiang and Inner Mongolia in my country. Animal parasitic diseases have a huge impact on the healthy development of animal husbandry, bring serious economic losses, and hinder the healthy development of animal husbandry. At the same time, zoonotic parasitic diseases have an impact on the quality of livestock and poultry products, seriously threatening people's health and public health safety. At present, the vaccine prevention technology for most parasitic diseases is very limited, and the main means of prevention and control of animal parasitic d...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K9/08A61K31/277A61K47/32A61K47/44A61K47/22A61K47/38A61P33/10
CPCA61K9/08A61K9/0053A61K31/277A61K47/22A61K47/32A61K47/38A61K47/44
Inventor 叶伟庆焦晓军焦伟丽蒲静君黄海洪
Owner FOSHAN NANHAI EASTERN ALONG PHARMA CO LTD
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