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Oral mouthwash for tumor patients

A technology of gargle for cancer patients, applied in the field of oral care, can solve problems such as regeneration, inability to organize, and poor safety performance, and achieve the effects of keeping the mouth clean, removing bad breath, and inhibiting or eliminating free radicals

Inactive Publication Date: 2017-05-31
JIANGSU SOLOMON BROTHER MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Although this suspension composition has analgesic, anti-inflammatory and mucosal repair effects, it can be used to treat oral mucositis caused by radiotherapy and chemotherapy and severe oral ulcers caused by anaerobic bacteria, but some raw materials (such as local anesthetics) contained therein It still has side effects such as obvious irritation and central inhibition, poor safety performance, and cannot regenerate tissues, inhibit or eliminate free radicals, and cannot avoid or delay the occurrence of severe oral mucositis during the treatment of tumor patients

Method used

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  • Oral mouthwash for tumor patients

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specific Embodiment

[0028] The sugar alcohol humectant is preferably sorbitol. The sugar alcohol sweetener is one or more of xylitol, mannitol and maltitol. The tea extract is preferably a green tea extract. Specific examples are as follows:

[0029] The raw material formulations of the oral gargle used for tumor patients in Examples 1-8 are shown in Table 1.

[0030] Table 1: The raw material formula situation (unit is kilogram) of embodiment 1-8.

[0031]

[0032] In each embodiment, the total weight of raw materials is 100 kg, wherein the amount of deionized water added is determined by subtracting the weight of other raw materials from 100 kg.

[0033] The invention can be used to inhibit the growth of bacteria in the oral cavity by adding an appropriate amount of sodium chloride, thereby reducing pathogenic bacteria.

[0034] In the oral gargle of the present invention, the main components of peppermint extract are flavonoids, polyphenols, terpenoids, amino acids and other components,...

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Abstract

The invention relates to oral mouthwash for tumor patients, and relates to the technical field of oral care. The oral mouthwash for the tumor patients is prepared from the following components in percentage by weight: 3 to 15 percent of a sugar alcohol moisturizer, 1 to 2 percent of ethanol, 5 to 15 percent of fructus chebulae extract, 2 to 15 percent of herba menthae extract, 0.05 to 2 percent of sodium benzoate, 2 to 3.5 percent of spirulina blue, 0.9 to 2 percent of sodium chloride, 0.2 to 4 percent of a sugar alcohol sweetening agent, 2 to 15 percent of tea leaf extract, 0.1 to 1 percent of cetylpyridinium chloride and the balance of deionized water. The oral mouthwash disclosed by the invention adopts plant components, is safe, has no side effects, has the functions of stopping pain, inhibiting bacteria and resisting viruses and the effect of inhibiting or removing free radicals, and is capable of effectively avoiding or delaying the occurrence of moderately severe oral mucositis during a treatment process of the tumor patients.

Description

technical field [0001] The invention relates to an oral gargle for tumor patients and relates to the technical field of oral care. Background technique [0002] Xerostomia and oral mucositis can be caused in varying degrees during radiotherapy and chemotherapy in cancer patients. While chemotherapy drugs inhibit or kill tumor cells, they can also have obvious toxic effects on the oral mucosal tissues that are renewing faster, and oxygen free radicals are generated accordingly, thus causing a series of symptoms of oral mucositis, such as, first, oral mucosal atrophy , thinning, increased fragility, followed by inflammatory reactions, pain and ulcers. For some head and neck radiotherapy patients, salivary glands and submandibular glands are often within the range of irradiation. After radiation irradiation, in addition to the decrease in saliva secretion, it will also cause changes in its properties, making saliva viscous and pH lower, thereby destroying the saliva. The lubr...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/41A61K9/08A61K47/26A61P35/00A61P1/02A61P29/00A61P31/02A61P31/04A61P31/12A61K36/82A61K31/44
CPCA61K9/0053A61K9/08A61K31/44A61K36/185A61K36/534A61K36/82A61K38/41A61K47/26A61K2236/333A61K2236/55A61K2300/00
Inventor 贾宁张晓晴
Owner JIANGSU SOLOMON BROTHER MEDICAL TECH CO LTD
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