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Application of pachymic acid A for preparing diuretic medicine

A technology of pachymic acid and diuresis, which can be used in drug combinations, medical preparations containing active ingredients, and pharmaceutical formulas, and can solve problems such as waste of poria cocos

Active Publication Date: 2017-03-15
NORTHWEST UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Poria cocos skin is the outer skin of Poria cocos sclerotium. When processing Poria cocos, only the inner sclerotia of Poria cocos, that is, white tuckahoe cocos, is used. When processing white tuckahoe cocos, the poria cocos skin and cut pieces are treated as waste, resulting in a great waste of tuckahoe cocos.

Method used

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  • Application of pachymic acid A for preparing diuretic medicine
  • Application of pachymic acid A for preparing diuretic medicine
  • Application of pachymic acid A for preparing diuretic medicine

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Embodiment Construction

[0008] The present invention uses pachymic acid A to prepare diuretic drugs and use them in the form of conventional pharmaceutical preparations; the conventional pharmaceutical preparations contain pharmaceutically acceptable carriers as active components in the preparation, such as suitable for enteral and parenteral Mixed with organic or inorganic solid or liquid excipients for administration, the pharmaceutical preparation can be in solid form such as capsules, tablets, pills, powders, granules and the like. The above preparations may contain stabilizers, wetting agents, excipients and other commonly used additives, such as cornstarch, stearic acid, olive oil, citric acid, lactose, ethylene glycol, magnesium stearate, gelatin, gypsum powder, agar , Ascorbic acid, etc. The above-mentioned preparations can be prepared according to the conventional preparation techniques of various preparations.

[0009] In order to verify the diuretic effect of pachymic acid A, the inventor...

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Abstract

The invention relates to application of pachymic acid A for preparing a diuretic medicine. Research results of the application show that pachymic acid A has a remarkable diuretic function on a water retention rat with normal saline burden, has a diuretic effect of retaining potassium and discharging sodium, and can provide a diuretic candidate medicine as a novel aldosterone antagonist or selective aldosterone receptor retardant in clinical application.

Description

technical field [0001] The present invention relates to the new drug application of pachymic acid A, in particular to the application of pachymic acid A in preparing diuretic medicine. Background technique [0002] Poria cocos is the dry sclerotia of Poria cocos (Poria cocos), a fungus of Polyporaceae, also known as pine cocos, pine potato, etc. Poria cocos was first recorded in "Shen Nong's Materia Medica". Poria cocos is flat in nature, sweet and light in taste, and returns to the heart, lung, spleen and kidney channels. Poria is a commonly used traditional Chinese medicine for invigorating the spleen and stomach, diuresis and dampness, and calming the mind; clinical use is divided into Poria, Fushen, Chi Fuling, etc. Poria has been a very important traditional Chinese medicine for both medicine and food since ancient times. There are ten medicines According to the theory of Nine Poria Cocos, Poria Cocos is listed as the top grade. The main active ingredients of Poria co...

Claims

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Application Information

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IPC IPC(8): A61K31/575A61P7/10
CPCA61K31/575
Inventor 赵英永陈华王明
Owner NORTHWEST UNIV
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