Application of niclosamide ethanolamine salt in preparing diabetes type 1 treating medicines
A technology of niclosamide ethanolamine salt and type 1 diabetes mellitus, which is applied in the application field of preparing medicines for preventing and treating type 1 diabetes mellitus and its complications, and can solve the disability and fatality rate, the tendency of spontaneous ketosis, serious complications, etc. problems, to achieve the effect of lowering blood sugar, increasing serum insulin levels, and improving muscle function
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[0024] Embodiments of the present invention will be specifically described below in conjunction with the accompanying drawings.
[0025] Type 1 diabetes is mainly due to the absolute lack of insulin caused by the destruction of pancreatic β cells, which in turn leads to elevated blood sugar, severe complications, high disability and death rates. sugar drug.
[0026] The present invention aims to observe the prevention and treatment effect of NEN on type 1 diabetes and its complications.
[0027] 1. Experimental method
[0028] 1. Animal model: 8-week-old male C57BL / 6 mice (body weight 18-22 g) were purchased from Guangdong Medical Experimental Animal Center. Animal experiments were carried out in strict accordance with the animal ethics guidelines and regulations of Guangzhou University of Traditional Chinese Medicine. The experimental animals were controlled at a constant room temperature of 20±1° C., with 12-hour light and 12-hour dark cycles, while free to eat and drink....
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