Automatic collection device for ampoule samples based on sterility testing process

Abstract

The invention discloses an automatic ampoule bottle sample collecting device based on a sterility detection process. A special alloy blade is designed to carry out pretreatment on ampoule bottles, the blade leaves a scratch in the bottle neck position of each ampoule bottle so that the following cutting step can be prepared for, every three ampoule bottles are fixed with three fixing racks in one set, nipples of every three ampoule bottles are knocked off at a time through three knocking hammers, and a special mechanism is used for removing broken glass; and after cutting of the ampoule bottles is completed, liquid medicine in the ampoule bottles is sucked through three syringes via peristaltic pumps, the liquid medicine is conveyed into sample concentration bottles, and the sample concentration process is completed. The automatic ampoule bottle sample collecting device can collect liquid medicine in thirty bottles in one batch, and meanwhile, the possibility that the liquid medicine is contaminated by grinding wheel particulates and glass is reduced. In addition, the automatic ampoule bottle sample collecting device is simple in structure, convenient to assemble and disassemble and small in occupied space, and automatic operation is easily achieved.

Description

technical field [0001] The invention belongs to the field of food and drug testing, and relates to a device for automatically collecting samples of ampoule bottles. Background technique [0002] In recent years, many food and drug quality and safety incidents have occurred in my country, making the government and the public attach great importance to the quality assurance of food and drugs. As a key item of food and drug quality control, sterility inspection is clearly required in the latest 2010 edition of GMP "Good Manufacturing Practice for Drugs" and the 2015 edition of the Pharmacopoeia. It is an important item for enterprises and regulatory agencies to inspect qualified products. Routine sterility inspection installs a unidirectional airflow laminar flow table in a controlled environment, and places a bacterium collector on the laminar flow table to complete the sterility test. The sterility tester includes a sterile isolator, a membrane filtration system (bacteria co...

AI Technical Summary

Problems solved by technology

However, there are many unsafe factors in opening the ampoule bottle, for example: defective ampoule or wrong operation can cause the teat or even the bottle body to be broken when opening the ampoule, causing injury to medical staff and possible glass fragments falling into the liquid medicine causing pollution in

Particles from the glass and grinding wheel during the opening of the ampoule can also cause contamination of the liquid medicine

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