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Compound oral solution with pholcodine

An oral solution, pholcodine technology, applied in the field of medicine and health care, can solve the problems of more and more adverse reactions, great addiction, abuse, etc., and achieve the effect of improving autoimmunity, small side effects, and convenient use

Pending Publication Date: 2017-01-11
南昌立健药业有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0004] At present, the central antitussive drugs that are widely used in the market are codeine phosphate and dextromethorphan hydrobromide: codeine phosphate has a relatively high degree of addiction, and there have been many abuse accidents in the market and have been criticized by the state. Strict control by the Food and Drug Administration; dextromethorphan hydrobromide has a good antitussive effect, but now there are more and more cases of adverse reactions, and there are also a large number of abuse incidents. The U.S. Food and Drug Administration always pays attention to the right Abuse of dextromethorphan and warnings not to abuse dextromethorphan

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0019] A compound oral solution containing phorcodine, characterized in that the main raw materials in parts by weight are: 4 parts of pholcodine, 6 parts of phenylacrylidine hydrochloride, 2 parts of glutathione, 15 parts of Radix Radix, stevia 5 parts of sugar, 8 parts of Artemisia annua, 4 parts of ginger, 4 parts of Andrographis paniculata, 4 parts of jujube seed, 2 parts of licorice, 1 part of taurocholic acid, 2 parts of honey, 0.2 parts of Puer tea extract, 0.2 parts of celery leaf extract , 0.2 part of blueberry extract; the preparation method of the Pu’er tea extract is to pulverize the Pu’er tea leaves after drying, then soak in ethanol and ultrasonic extraction, and finally recrystallize the gained; the preparation method of the celery leaf extract is to make the celery The leaves are washed, dried, beaten, treated with papain, ultrafiltered and centrifuged, and finally recrystallized; the blueberry extract is prepared by beating and stirring the blueberries, extract...

Embodiment 2

[0023] A compound oral solution containing phorcodine, characterized in that the main raw materials in parts by weight are: 4.6 parts of pholcodine, 6 parts of phenylacryl hydrochloride, 2 parts of glutathione, 16 parts of Radix Radix, stevia 7 parts of sugar, 9 parts of Artemisia annua, 5 parts of ginger, 4 parts of Andrographis paniculata, 4 parts of jujube seed, 2 parts of licorice, 1 part of taurocholic acid, 2 parts of honey, 0.2 parts of Puer tea extract, 0.2 parts of celery leaf extract , 0.2 part of blueberry extract; the preparation method of the Pu’er tea extract is to pulverize the Pu’er tea leaves after drying, then soak in ethanol and ultrasonic extraction, and finally recrystallize the gained; the preparation method of the celery leaf extract is to make the celery The leaves are washed, dried, beaten, treated with papain, ultrafiltered and centrifuged, and finally recrystallized; the blueberry extract is prepared by beating and stirring the blueberries, extracting...

Embodiment 3

[0027] A compound oral solution containing phorcodine, characterized in that the main raw materials in parts by weight are: 5 parts of pholcodine, 7 parts of phenylacrylidine hydrochloride, 3 parts of glutathione, 18 parts of Radix Radix, stevia 9 parts of sugar, 10 parts of Artemisia annua, 7 parts of ginger, 6 parts of Andrographis paniculata, 6 parts of jujube seed, 4 parts of licorice, 2 parts of taurocholic acid, 3 parts of honey, 0.3 parts of Pu'er tea extract, 0.3 parts of celery leaf extract , 0.3 part of blueberry extract; the preparation method of the Pu’er tea extract is to pulverize the Pu’er tea leaves after drying, then soak in ethanol and ultrasonic extraction, and finally recrystallize the gained; the preparation method of the celery leaf extract is to make the celery The leaves are washed, dried, beaten, treated with papain, ultrafiltered and centrifuged, and finally recrystallized; the blueberry extract is prepared by beating and stirring the blueberries, extr...

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PUM

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Abstract

The invention discloses a compound oral solution containing pholcodine, prepared from, by weight, 4-6 arts of pholcodine, 6-8 parts of triprolidine, 2-4 parts of glutathione, 15-20 parts of radix isatidis, 5-12 parts of stevioside, 8-12 parts of artemisia apiacea, 4-10 parts of fresh ginger, 4-8 parts of andrographis paniculata, 4-8 parts of semen ziziphi spinosae, 2-6 parts of liquorice root, 1-2 parts of taurocholic acid, 2-4 parts of honey, 0.2-0.4 parts of Pu-erh tea extract, 0.2-0.4 parts of celery leaf extract, and 0.2-0.4 parts of blueberry extract; Compared with the prior technology, the compound oral solution has synergistic effect between the raw material components, the treatment effect is well with quick effect, the drug resistance is small, the medicinal safety is high, the side effect is small, the stability is good, the shelf life is long , which is easy to carry, the preparing process is simple, suitable for large-scale production and so on.

Description

technical field [0001] The invention relates to the field of medicine and health care, in particular to a compound oral solution containing pholcodine. Background technique [0002] Influenza is a common respiratory disease caused by a variety of viruses, and has a high incidence rate. At present, the more practical treatment method is to relieve cold symptoms through a combination of antipyretic and analgesics, nasal decongestants, antihistamines and central cough suppressants - fever caused by colds, headache, sore limbs, sneezing , runny nose, stuffy nose, cough, etc. [0003] Central antitussives have strong antitussive effect and have mild sedative and analgesic effects; antipyretic and analgesic drugs have antipyretic effect while relieving pain; decongestants can relieve nasal congestion symptoms and relieve cough; Amine medicines can relieve allergic symptoms such as sneezing in colds, and these medicines have the characteristics of drowsiness. If the preparations ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/06A61K9/08A61P31/14A61P11/00A61P37/04A61K35/644A61K31/704A61K31/57A61K31/5377A61K31/4439
CPCA61K31/704A61K9/08A61K31/4439A61K31/5377A61K31/57A61K35/644A61K36/19A61K36/195A61K36/23A61K36/282A61K36/315A61K36/45A61K36/484A61K36/725A61K36/82A61K36/9068A61K38/06A61K2236/19A61K2236/333A61K2236/35A61K2236/51A61K2236/53A61K2300/00
Inventor 郑玲英
Owner 南昌立健药业有限公司
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