Wireless infrared remote control optogenetic system

Abstract

The invention discloses a wireless infrared remote control optogenetic system. An infrared emitting end comprises a power supply driving board, infrared emitting tube lamp strips, a signal source and a 5V power supply; and an infrared receiving end comprises an infrared receiving pipe, a 3.7V lithium battery, a comparison circuit and blue light emitting diodes. The lighting and extinguishing of the infrared emitting tube lamp strips are controlled through controlling on-off states of the power supply by virtue of a signal source, so that the infrared emitting tube lamp strips are basically equally bright and can synchronously shine or go out; and the infrared receiving pipe is used for receiving infrared signals of infrared emitting tubes of the infrared emitting tube lamp strips, the lighting and extinguishing of blue infrared emitting diodes are controlled through the comparison circuit, and optical signals of the blue light emitting diodes are guided into biological cells through optical fibers, thereby realizing effective photic stimulation. The wireless infrared remote control optogenetic system can be remotely and wirelessly operated and controlled in an experimental box and is small in volume, high in integration level and compact in structure; and remote control signals of the signal source can be accurately and timely responded, and the infrared remote control range is wide, so that the free activities of mice in a large scope are not influenced, and the system is beneficial to the large-scale behavioral experiments.

Description

technical field [0001] The invention relates to a method and system for light stimulation of optogenetic technology, in particular to a wireless infrared remote control optogenetic system. Background technique [0002] Optogenetics technology is a method to precisely control cell activity by combining optical technology and genetic technology. Using optogenetics technology, neuroscience researchers can deeply explore the relationship between neurons in a nucleus. Position and relationship, understand the internal interaction between multiple nuclei, so as to have a clearer understanding of the structure and function of the brain structure and nervous system. In addition to conducting basic research on neuronal structure, more importantly, using this set of equipment and some animal disease models, it is possible to explore the effects of common neurological diseases such as Parkinson's disease, Alzheimer's disease, depression, etc. Brain pathological changes, understand the...

AI Technical Summary

Problems solved by technology

However, the domestic and foreign optogenetic device production markets are still in their infancy.

[0004] At present, optogenetic devices are mostly wired devices, which use optical fiber to transmit stimulating light or require the mouse's head to be fixed, while the wireless device is too large and heavy to restrict the free movement of the mouse, so it is impossible to distinguish whether it is due to the light stimulation or the device. The restrictions have an impact on the behavior of mice, which greatly affects the scientific nature of the experiment

In addition, the use of wireless charging in wireless power supply also increases the complexity and cost of the system, making it impossible for biological experiments to be carried out in ordinary biobehavioral experiment boxes.

Images