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Traditional Chinese medicine composition for preventing and treating skin lesion aging and application thereof

A technology for skin lesions and compositions, applied in the field of traditional Chinese medicine compositions for the prevention and treatment of skin lesions and aging, to achieve the effect of improving the therapeutic effect and shortening the onset time

Active Publication Date: 2016-11-09
SHANDONG UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The effectiveness of traditional Chinese medicine in treating diseases is well established, but its mechanism of action still deserves to be studied

Method used

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  • Traditional Chinese medicine composition for preventing and treating skin lesion aging and application thereof
  • Traditional Chinese medicine composition for preventing and treating skin lesion aging and application thereof
  • Traditional Chinese medicine composition for preventing and treating skin lesion aging and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0045] Embodiment 1: the preparation of the traditional Chinese medicine composition of preventing and treating skin lesion aging

[0046] 1. Preparation of Siberia chinensis extract, coltsfoot flower extract, licorice extract and angelica extract:

[0047] (1) Wexgrass extract:

[0048] Take 200 g of Siberia chinensis, pulverize it, extract it twice with 800 mL of 75% ethanol (volume fraction), and reflux for 1 hour each time, combine the extracts, concentrate and dry, and obtain the product.

[0049] (2) Coltsfoot flower extract:

[0050] Take 200 g of winter flowers, pulverize them, and use 1000 mL of 70% ethanol (volume fraction), reflux extraction twice, each time for 0.5 hours, combine the extracts, concentrate and dry, to obtain.

[0051] (3) Licorice extract:

[0052] Take 200g of licorice root, pulverize it, extract with 1000mL of 75% ethanol (volume fraction), reflux twice for 1 hour each time, combine the extracts, concentrate and dry to obtain the product.

[0...

Embodiment 2

[0056] Embodiment 2: the preparation of the traditional Chinese medicine composition of preventing and treating skin lesion aging

[0057] 1. The preparation method of Siberia chinensis extract, coltsfoot flower extract, licorice extract and angelica extract is the same as in Example 1.

[0058] 2. Take above-mentioned four kinds of traditional Chinese medicine extracts by weighing, and the weight is respectively 1.0 grams of Herba chinensis extract, 2.5 grams of Coltsfoot flower extract, 0.5 grams of Glycyrrhizae extract, 1.5 grams of Angelica sinensis extract, mix well, and pulverize into fine powder, namely Obtain the Chinese medicine composition.

Embodiment 3

[0059] Embodiment 3: the preparation of the traditional Chinese medicine composition of preventing and treating skin lesion aging

[0060] 1. The preparation method of Siberia chinensis extract, coltsfoot flower extract, licorice extract and angelica extract is the same as in Example 1.

[0061] 2. Take by weighing the above four kinds of Chinese medicine extracts, the weights are respectively 1.5 grams of Herba Jubilata extract, 1.5 grams of Coltsfoot flower extract, 0.5 grams of licorice extract, and 0.5 grams of Angelica extract, mix well, and be ground into fine powder, namely Obtain the Chinese medicine composition.

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Abstract

The invention discloses a traditional Chinese medicine composition for preventing and treating skin lesion aging. The traditional Chinese medicine composition is prepared from 10-15 parts of herba siegesbeckiae extract, 15-25 parts of flos farfarae extract, 5-15 parts of licorice extract and 5-15 parts of radix angelica sinensis extract. The herba siegesbeckiae extract, the flos farfarae extract, the licorice extract and the radix angelica sinensis extract are prepared through the following method comprising the steps that herba siegesbeckiae, flos farfarae, liquorice roots and radix angelica sinensis are subjected to reflux extraction 1-6 times with 30-100% ethyl alcohol, the use amount of a solvent is 1-15 times of the weight of the medicinal materials every time, and the extraction time ranges from 0.5 h to 10 h every time; extraction solutions are combined and filtered, ethyl alcohol is recycled, concentration and drying are carried out, and then the traditional Chinese medicine composition is obtained. The traditional Chinese medicine composition has the functions of resisting oxidative stress and inflammation, the level of glutathione in human epidermis HaCaT cells can be increased, arsenic induced cytotoxicity is resisted, forming of arsenic induced reactive oxide species is inhibited, and the traditional Chinese medicine composition can be used for preparing medicine or cosmetics for preventing and treating skin injuries and inflammation lesion and delaying skin aging.

Description

technical field [0001] The present invention relates to a traditional Chinese medicine composition for preventing and treating skin pathological changes and aging and its application, in particular to a traditional Chinese medicine composition composed of four kinds of Chinese medicine extracts, namely, Juxtapositiona, coltsfoot, licorice and angelica, and the preparation of the Chinese medicine composition Drugs for the prevention and treatment of skin damage and inflammatory lesions, as well as cosmetics for delaying skin aging. Background technique [0002] Human skin is directly exposed to the external environment, directly in contact with pollutants in the atmosphere, ozone, ultraviolet rays and harmful components in the environment, and is vulnerable to infringement and damage. In the process of my country's rapid industrialization and modernization, environmental pollution is also becoming more and more serious, such as carbon, sulfur and nitrogen oxides (CO, SO 2 , ...

Claims

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Application Information

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IPC IPC(8): A61K36/484A61P17/00A61P17/18A61K8/97A61Q19/00A61Q19/08
CPCA61K8/97A61K36/232A61K36/28A61K36/484A61K2236/333A61K2236/39A61K2800/75A61K2800/78A61Q19/00A61Q19/08A61K2300/00
Inventor 沈涛周明星任冬梅王小宁娄红祥
Owner SHANDONG UNIV
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