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Ground beeltle biological activity small peptide composition

A technology of ground beetle and composition, which is applied in the field of traditional Chinese medicine, can solve the problems of recurring freckles, the inability to achieve freckle and whitening effects, etc., and achieve the effects of reducing blood viscosity, stable curative effect, and strong sweet taste

Inactive Publication Date: 2016-05-11
ANHUI BIOLOGICAL PEPTIDE IND RES INST
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, Western medicine mainly uses the bleaching effect of vitamin C, mercury, arsenic, lead and other heavy metals to remove pigmented spots and whiten the skin.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0062] Prescription: Wood beetle small peptide 30g Rehmannia glutinosa total polysaccharide 50g Angelica total phenolic acid 40g Licorice total flavonoids 30g

[0063] Preparation method: Preparation of small wood beetle peptides: Take ground beetle medicinal materials, crush them through an 80-mesh sieve, add 10 times the amount of water and boil for 15 minutes, wait to cool to 40°C, adjust the pH to 1.5-2.0 with dilute hydrochloric acid solution, add 1% wood beetle Insect pepsin, heat at 40°C for 1 hour, adjust pH to 7.5-8.0 with 20% sodium hydroxide solution, add 1% wood beetle trypsin, heat at 40°C for 3 hours, heat and boil for 15 minutes, reduce pressure Concentrate and dry to obtain the small wood beetle peptide; wherein the content of the small wood beetle peptide is not less than 60%.

[0064] Preparation of total polysaccharides of Rehmannia glutinosa: Take the dried rehmannia glutinosa, add 8 times the amount of water, extract twice at 98-100°C for 4 hours each time...

Embodiment 2

[0069] Prescription: Wood Beetle Peptide 200g Rehmannia glutinosa total polysaccharide 400g Angelica total phenolic acid 300g Licorice total flavonoids 100g

[0070] Preparation method: Preparation of small wood beetle peptides: Take ground beetle medicinal materials, crush them through an 80-mesh sieve, add 10 times the amount of water and boil for 15 minutes, wait to cool to 40°C, adjust the pH to 1.5-2.0 with dilute hydrochloric acid solution, add 1% wood beetle Insect pepsin, heat at 40°C for 1 hour, adjust pH to 7.5-8.0 with 20% sodium hydroxide solution, add 1% wood beetle trypsin, heat at 40°C for 3 hours, heat and boil for 15 minutes, reduce pressure Concentrate and dry to obtain the small wood beetle peptide; wherein the content of the small wood beetle peptide is not less than 60%.

[0071] Preparation of total polysaccharides of Rehmannia glutinosa: Take the dried rehmannia glutinosa, add 8 times the amount of water, extract twice at 98-100°C for 4 hours each time, ...

Embodiment 3

[0076] Prescription: Wood beetle small peptide 4kg Rehmannia glutinosa total polysaccharide 6kg Angelica total phenolic acid 5kg Licorice total flavonoids 5kg

[0077] Preparation method: Preparation of small wood beetle peptides: Take ground beetle medicinal materials, crush them through an 80-mesh sieve, add 10 times the amount of water and boil for 15 minutes, wait to cool to 40°C, adjust the pH to 1.5-2.0 with dilute hydrochloric acid solution, add 1% wood beetle Insect pepsin, heat at 40°C for 1 hour, adjust pH to 7.5-8.0 with 20% sodium hydroxide solution, add 1% wood beetle trypsin, heat at 40°C for 3 hours, heat and boil for 15 minutes, reduce pressure Concentrate and dry to obtain the small wood beetle peptide; wherein the content of the small wood beetle peptide is not less than 60%.

[0078] Preparation of total polysaccharides of Rehmannia glutinosa: Take the dried rehmannia glutinosa, add 8 times the amount of water, extract twice at 98-100°C for 4 hours each time...

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Abstract

The invention discloses a ground beeltle biological activity small peptide effective part composition used for removing spots and whitening skin, and belongs to the field of traditional Chinese medicine. The composition is prepared from ground beeltle small peptide extracted from ground beeltles, prepared rehmannia root total polysaccharides extracted from rehmannia roots, angelica sinensis total phenolic acid extracted from angelica sinensis and licorice root total flavonoids extracted from licorice roots according to a certain matching ratio. Conventional auxiliary materials in pharmacy are added, and the composition is prepared in various dosage forms and can be clinically used for treating pigmented spots, whitening skin and reducing pigmentogenesis.

Description

technical field [0001] The invention relates to a traditional Chinese medicine effective part composition with freckle-removing and whitening effects and a preparation method thereof, in particular to a small biologically active peptide of ground beetle extracted from wood beetle, total polysaccharide of rehmannia glutinosa extracted from rehmannia glutinosa, rehmannia glutinosa total polysaccharide extracted from angelica The invention relates to a traditional Chinese medicine active part composition composed of extracted total phenolic acids of angelica and total flavonoids of licorice extracted from licorice and a preparation method thereof, belonging to the field of traditional Chinese medicines. Background technique [0002] The color of human skin is mainly determined by the activity of melanin synthesized by melanocytes, environmental factors such as ultraviolet rays, exhaust gas, active oxygen, foods rich in copper, iron, zinc and other metals, and certain diseases su...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K38/01A61P17/00A61K36/804A61K35/64
CPCA61K38/012A61K47/06A61K47/26A61K47/32A61K47/44A61K9/06A61K35/63A61K36/232A61K36/484A61K36/804A61K2236/53A61K2236/39A61K2236/55A61K2236/333A61K2236/331A61K2300/00
Inventor 代龙刘国飞刘元涛
Owner ANHUI BIOLOGICAL PEPTIDE IND RES INST
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