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Traditional Chinese medicine composition for treating senile vaginitis and preparation method thereof

A technology for vaginitis and senility, which is applied in the field of traditional Chinese medicine composition and its preparation for the treatment of senile vaginitis, and can solve the problems of increased risk of endometrial cancer and breast cancer, easy destruction of normal vaginal flora, increase of estrogen, etc. problem, to achieve drug safety, good compliance, and the effect of relieving itching symptoms

Inactive Publication Date: 2011-08-10
南通市星期七旅游开发有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The short-term curative effect is better, but long-term application of estrogen will increase the level of estrogen in the blood, which will increase the risk of endometrial cancer and breast cancer
In addition, long-term use of antibiotics can easily destroy the normal vaginal flora, resulting in an increased recurrence rate

Method used

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  • Traditional Chinese medicine composition for treating senile vaginitis and preparation method thereof
  • Traditional Chinese medicine composition for treating senile vaginitis and preparation method thereof
  • Traditional Chinese medicine composition for treating senile vaginitis and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0062]The preparation method of the honey refining pill of the present invention is as follows: get Epimedium 1000g, Angelica 1000g, Atractylodes macrocephala 1000g, Motherwort 1000g, Astragalus 1000g, peach kernel 1000g, Cuscuta 1000g, Ligustrum lucidum 1000g, mulberry 1000g, Shouwu 1000g, Eclipta 1000g, raspberry 1000g, scutellaria baicalensis 1000g, dogwood 1000g, gardenia 1000g, chuanxiong 1000g; firstly crush the raw material drug for oral administration into coarse powder, then further pulverize, pass through 100 mesh to 120 mesh sieve, so that the fine powder that can pass through the sieve When the amount reaches 30%, collect the fine powder that passes through the sieve to obtain fine powder a; then put the coarse powder that cannot pass through the 120 mesh sieve into a multi-functional extraction tank for extraction twice, add 10 times the amount of water for the first time and decoct for 1 hour, the second time Add 8 times the amount of water for the second time and...

experiment example 2

[0078] Experimental example 2: long-term toxicity test data

[0079] 1. Experimental method

[0080] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean the depilatory agent, observe each group of guinea pigs after 24 hours to be coated with respectively 0.2,0.4 and 0.8ml of the present invention's orally administered traditional Chinese medicine preparation Honey Refined Pills, contain crude drug 92,184 and 368mg respectively, another group is coated with vehicle 0.8ml twice a day, For 30 consecutive days, the general condition of the guinea pigs was observed. After the experiment, the animals were sacrificed for hematology, blood biochemical and pathological examinations.

[0081] 2. Results

[0082] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of ​​g...

experiment example 3

[0083] Experimental example 3: Cumulative toxicity test:

[0084] Traditional Chinese medicine preparation of the present invention is taken orally honey refined pills to mice by 7.69, 19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine of the present invention The preparation has no obvious effect on the hair, behavior, defecation, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of rats. After 1 week and 3 weeks after stopping the drug, there was no significant change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.

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Abstract

The invention discloses a traditional Chinese medicine composition for treating senile vaginitis; the oral medicine includes: herba epimedii, angelica sinensis, rhizoma atractylodis macrocephalae, motherwort, astragalus mongholicus, peach kernel, cuscuta chinensis, fructus ligustri lucidi, mulberry, radix polygonum multiflorum, eclipta alba, raspberry, scutellaria baicalensis, dogwood, cape jasmine and ligusticum wallichii; and the external medicine includes: myrrh, radix sophorae flavescentis, fructus cnidii, oldenlandia diffusa, Chinese violet, radix stemonae, sargent gloryvine, patrinia, golden cypress, safflower, fructus kochiae, pearl and motherwort. The traditional Chinese medicine composition in the invention has androgen-like action and estrogen-like action, and can enhance resistance of senile vagina and urethra mucosa; the contained polysaccharide and general flavone components further have antioxidant and anti-aging effects. The traditional Chinese medicine composition further has the effects of clearing heat and detoxicating, killing parasites to relieve itching, and can be used for treating the senile vaginitis and relieving symptoms such as itching, and can diminish inflammation and disinfect; and the traditional Chinese medicine composition is obvious in medical effect, safe in administration, simple and good in compliance of old patients.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine composition for treating senile vaginitis and a preparation method thereof. Background technique [0002] Senile vaginitis is common in postmenopausal elderly women. Due to ovarian function decline, many levels of estrogen decrease, vaginal wall atrophy, mucous membrane becomes thinner, glycogen content in epithelial cells decreases, vaginal Ph value increases, and local resistance decreases. Parents of pathogenic bacteria are easy to invade and reproduce and cause inflammation. The main symptoms are increased vaginal discharge and genital itching and burning sensation. Examination showed that the vagina showed senile changes, epithelial atrophy, folds disappeared, and the epithelium became smooth and thin. The vaginal mucosa is congested, with small bleeding spots, and sometimes superficial ul...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/744A61K36/904A61K9/02A61K9/48A61P15/02A61K35/56A61K35/618
Inventor 梁轶聪李佃场王漪
Owner 南通市星期七旅游开发有限公司
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