Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Traditional Chinese medicine composition and fingerprint detection method of raw material herb of traditional Chinese medicine composition

A fingerprint and detection method technology, applied in the field of quality inspection of traditional Chinese medicine preparations, can solve problems such as low detection efficiency, cumbersome detection work, and poor response to the overall quality of preparations, so as to achieve high-quality stability and ensure safety and effectiveness. Effect

Inactive Publication Date: 2016-05-04
JIANGSU KANION PHARMA CO LTD
View PDF4 Cites 3 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, the quality standards of the above-mentioned traditional Chinese medicine composition stipulate the identification and detection of individual compounds. The detection work is cumbersome, the detection efficiency is low, and the number of active ingredients detected is limited, which cannot reflect the overall quality of the preparation well.

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Traditional Chinese medicine composition and fingerprint detection method of raw material herb of traditional Chinese medicine composition
  • Traditional Chinese medicine composition and fingerprint detection method of raw material herb of traditional Chinese medicine composition
  • Traditional Chinese medicine composition and fingerprint detection method of raw material herb of traditional Chinese medicine composition

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0069] The establishment and application of embodiment 1 Chinese medicine composition fingerprint

[0070] 1, the fingerprint detection method of described Chinese medicine composition, it may further comprise the steps:

[0071] (1) Preparation of the test solution: add 50% ethanol to the Chinese medicine composition and ultrasonically extract 2 times, each time for 30 minutes, the extract is centrifuged at 1500 to 3000 rpm, and the centrifuged liquid is filtered with a microporous membrane. Obtain the test solution;

[0072] (2) High-performance liquid chromatography measures the control fingerprint: get 10 batches of the Chinese medicine composition to prepare the test sample according to the method of step (1), inject samples under appropriate chromatographic conditions, and record the Chinese medicine composition of each batch Based on these fingerprints, the Chinese medicine chromatographic fingerprint similarity evaluation system (version 2004A) is used to calculate th...

Embodiment 2

[0082] The establishment and application of embodiment 2 Chinese medicine composition fingerprint

[0083] 1, the fingerprint detection method of described Chinese medicine composition, it may further comprise the steps:

[0084] (1) Preparation of the test solution: add 50% ethanol to the Chinese medicine composition and ultrasonically extract 2 times, each time for 30 minutes, the extract is centrifuged at 1500 to 3000 rpm, and the centrifuged liquid is filtered with a microporous membrane. Obtain the test solution;

[0085] (2) High-performance liquid chromatography measures the control fingerprint: get 10 batches of the Chinese medicine composition to prepare the test sample according to the method of step (1), inject samples under appropriate chromatographic conditions, and record the Chinese medicine composition of each batch Based on these fingerprints, the Chinese medicine chromatographic fingerprint similarity evaluation system (version 2004A) was used to calculate a...

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The present invention discloses a fingerprint detection method for a traditional Chinese medicine composition with effects of common cold prevention and treatment, and acute and chronic bronchitis prevention and treatment, and a traditional Chinese medicine composition raw material herb detection method. The fingerprint detection method comprises test substance solution preparation, control fingerprint establishment, and test substance solution fingerprinting determination. According to the present invention, the optimal mobile phase composition, the optimal gradient elution procedure, the optimal detection wavelength, the optimal chromatographic column, the optimal column temperature and other analysis conditions are screened through a large number of experiments, and the results of the multiple experiments verify that the fingerprint detection method can comprehensively, objectively and accurately detect and evaluate the quality of the traditional Chinese medicine composition, can guarantee the safety and the efficacy of the traditional Chinese medicine composition from the source, and can ensure the clinical treatment effect.

Description

technical field [0001] The invention relates to a quality inspection method of a traditional Chinese medicine preparation, in particular to a fingerprint detection method of a traditional Chinese medicine composition and its raw materials, which have the effect of preventing and treating colds and acute and chronic bronchitis. Background technique [0002] Chinese patent ZL02129192.6 discloses a traditional Chinese medicine composition with the effect of preventing and treating colds and acute and chronic bronchitis and its preparation method. become. The traditional Chinese medicine composition is produced by Jiangsu Kangyuan Pharmaceutical Co., Ltd. It has clinical effects of clearing heat and detoxifying, eliminating phlegm and relieving cough. Unable to spit, red tongue, yellow and greasy fur, etc. [0003] At present, the quality standards of the above-mentioned traditional Chinese medicine composition stipulate the identification and detection of individual compounds...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
Patent Type & Authority Applications(China)
IPC IPC(8): G01N30/02G01N30/06
Inventor 萧伟胡军华林夏章晨峰
Owner JIANGSU KANION PHARMA CO LTD
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com