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Application of compound traditional Chinese medicine extract in preparing medicine for treating ovarian cysts

A technology of extracts and traditional Chinese medicines, applied in the field of application of traditional Chinese medicine combination extracts in the preparation of drugs for the treatment of ovarian cysts, can solve problems such as unsuitable for widespread use, degeneration and necrosis of diseased tissues, and cure the symptoms but not the root cause, and achieve the elimination or reduction of uterine cysts. Fibroids and ovarian cysts, less toxic and side effects, and remarkable results

Inactive Publication Date: 2016-03-23
YUYAO WANZHEN HARDWARE FACTORY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0008] At present, the treatment of ovarian cysts at home and abroad mostly uses surgery, chemotherapy, radiotherapy, etc., but most of them are difficult to cure. Surgical resection is prone to side effects such as pelvic adhesions. After surgery, the tumor will recur and grow again. high
Ultrasound interventional therapy is an advanced medical method for treating various cysts and fibroids. Under the guidance of ultrasound, it directly punctures the diseased tissue and injects drugs to make the diseased tissue rapidly dehydrate, degenerate, necrosis, and atrophy fibrosis. Expensive, same relapse
The medical field has no ideal specific drugs for the treatment of ovarian cysts. Although some drugs have certain effects on gynecological diseases such as ovarian cysts, their therapeutic effects are not obvious and their safety performance is low, so they should not be widely used.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The traditional Chinese medicine combination extract of the present invention is prepared from the following raw materials: 40 kg of Cyclocarya paliurus, 35 kg of hair lotus, 15 kg of white flower vine and 18 kg of phellinus.

[0023] The preparation method of the Chinese medicine combination extract is as follows:

[0024] (1) Grinding the raw materials separately, passing through a 100-mesh sieve, using supercritical carbon dioxide extraction technology, the extraction temperature is 60°C, the extraction pressure is 12MPa, and the extraction time is 2h, and the extracted volatile oil is collected to obtain extract A, which is set aside;

[0025] (2) The extract A obtained in step (1) is used as a solvent with a concentration of 95% ethanol, and is extracted by warm soaking at 80 ° C. The number of extractions is 5 times, and the extraction time is 2 hours each time. The solvent consumption is 1 / 2 of the total weight of raw materials 12 times, filter, collect the extra...

Embodiment 2

[0028] The traditional Chinese medicine combination extract of the present invention is prepared from the following raw materials: 45 kg of Cyclocarya paliurus, 30 kg of hair lotus, 17.5 kg of white vine and 15 kg of phellinus.

[0029] The preparation method of the Chinese medicine combination extract is as follows:

[0030] (1) Grinding the raw materials separately, passing through a 90-mesh sieve, using supercritical carbon dioxide extraction technology, the extraction temperature is 60°C, the extraction pressure is 12MPa, and the extraction time is 3h, and the extracted volatile oil is collected to obtain extract A, which is set aside;

[0031] (2) The extract A obtained in step (1) is used as a solvent with a concentration of 95% ethanol, and is extracted by warm soaking at 75 ° C. The number of extractions is 5 times, and the extraction time is 3 hours each time. The solvent consumption is 1 / 2 of the total weight of raw materials 12 times, filter, collect the extract, re...

Embodiment 3

[0034] The traditional Chinese medicine combination extract of the present invention is prepared from the following raw materials: 50 kg of Cyclocarya paliurus, 25 kg of hair lotus, 20 kg of white flower vine, and 12 kg of Phellinus.

[0035] The preparation method of above-mentioned Chinese medicine combination extract is:

[0036] (1) Grinding the raw materials separately, passing through a 100-mesh sieve, using supercritical carbon dioxide extraction technology, the extraction temperature is 50°C, the extraction pressure is 12MPa, and the extraction time is 3h, and the extracted volatile oil is collected to obtain extract A, which is set aside;

[0037] (2) The extract A that step (1) obtains is used concentration 90% ethanol as solvent, and is extracted by warm soaking at 80 ℃, and the number of times of extraction is 5 times, and each extraction time is 3h, and each solvent consumption is 1 / 2 of the total weight of raw materials 12 times, filter, collect the extract, reco...

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Abstract

The invention discloses application of a compound traditional Chinese medicine extract in preparing medicine for treating ovarian cysts. The compound traditional Chinese medicine extract is prepared from cyclocarya paliurus, picris japonica, mucuna birdwoodiana Tutcher and phellinus igniarius (L. ex Fr.). The raw materials are smashed, screened and then extracted through the supercritical CO2 extraction technology, volatile oil is collected and extracted through ethanol, an extracting solution is collected after filtration, water is added for reflux extraction after concentration and drying, filtration is performed, an extracting solution is concentrated and passes through macroporous adsorption resin, elution is performed through water and then is performed through an ethanol solution, concentration and drying are performed, and the target compound traditional Chinese medicine extract is obtained. The compound traditional Chinese medicine extract can eliminate or reduce uterine fibroids and ovarian cysts, has a significant treatment effect on uterine fibroids and ovarian cysts and takes effect fast, and the effective rate can reach 99%; furthermore, the compound traditional Chinese medicine extract is low in cost, high in safety, small in toxic and side effect, capable of treating both symptoms and root causes of ovarian cysts and worthy of being widely applied and popularized clinically.

Description

technical field [0001] The invention relates to the technical field of preparation of traditional Chinese medicines, in particular to the application of a combination extract of traditional Chinese medicines in the preparation of medicines for treating ovarian cysts. Background technique [0002] Ovarian cyst is a general term for ovarian cystic masses, which is a kind of ovarian tumor in a broad sense. It can be affected by all ages, but it is most common in women aged 20-50. Ovarian tumor is a common tumor of female genitalia, which has a high degree of malignant transformation and is one of the most serious malignant tumors threatening women's lives. [0003] Clinical observation of ovarian cysts mainly manifests as: [0004] 1. Abdominal mass: Intra-abdominal mass below medium size, if there is no complication or malignant transformation, its biggest feature is mobility, which can often move from the pelvic cavity to the abdominal cavity. The mass is generally painless...

Claims

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Application Information

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IPC IPC(8): A61K36/52A61P15/08A61P35/00
CPCA61K36/52A61K9/0095A61K36/07A61K36/28A61K36/486A61K2236/331A61K2236/333A61K2236/37A61K2236/39A61K2236/51A61K2236/55
Inventor 沈婉珍
Owner YUYAO WANZHEN HARDWARE FACTORY
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