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Medicine composition for treating osteoarthritis and preparing technology thereof

A technology for osteoarthritis and composition, applied in the field of pharmaceutical composition for treating osteoarthritis and its preparation process, can solve the problems of weak curative effect and poor stability of oral liquid, and achieve good therapeutic effect and good anti-free radical and antioxidant activity, enhance the effect of human immunity

Active Publication Date: 2016-03-23
北京素维生物科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, there are still problems such as weak curative effect and poor stability of oral liquid.

Method used

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  • Medicine composition for treating osteoarthritis and preparing technology thereof
  • Medicine composition for treating osteoarthritis and preparing technology thereof
  • Medicine composition for treating osteoarthritis and preparing technology thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0036] The pharmaceutical composition for the treatment of osteoarthritis of the present embodiment is prepared by the following process:

[0037] Weigh raw materials: 25g glucosamine, 6g chondroitin sulfate, 4g taurine, 0.4g aspartame, 0.2g potassium phenylpropionate and 0.1g caramel color, and add the above-mentioned raw materials into 260g deionized water in turn , mix well to obtain an aqueous solution, and use a pH regulator to adjust the pH of the aqueous solution to 3. The aqueous solution with a pH of 3 is firstly filtered through a filter to remove various foreign substances brought in during the weighing and configuration process, and then finely filtered with a 0.22 μm microporous membrane to remove particles and bacteria to obtain a clear liquid, which is obtained after fine filtration liquid medicine. The aseptic filling process is adopted to fill the obtained medicinal liquid into a bottle, and to sterilize the filled bottled oral liquid to kill all the microorg...

Embodiment 2

[0039] The pharmaceutical composition for the treatment of osteoarthritis of the present embodiment is prepared by the following process:

[0040] Weigh raw materials: 35g glucosamine, 10g chondroitin sulfate, 7.5g taurine, 0.8g aspartame, 0.5g potassium phenylpropionate and 0.2g caramel color, and add the above-mentioned raw materials into 380g deionized In water, mix well to obtain an aqueous solution, and use a pH regulator to adjust the pH of the aqueous solution to 3. The aqueous solution with a pH of 3 is firstly filtered through a filter to remove various foreign substances brought in during the weighing and configuration process, and then finely filtered with a 0.22 μm microporous membrane to remove particles and bacteria to obtain a clear liquid, which is obtained after fine filtration liquid medicine. The aseptic filling process is adopted to fill the obtained medicinal liquid into a bottle, and to sterilize the filled bottled oral liquid to kill all the microorgani...

Embodiment 3

[0042] The pharmaceutical composition for the treatment of osteoarthritis of the present embodiment is prepared by the following process:

[0043] Weigh raw materials: 40g glucosamine, 15g chondroitin sulfate, 12g taurine, 1.2g aspartame, 0.8g potassium phenylpropionate and 0.4g caramel coloring, and add the above-mentioned raw materials into 500g deionized water in turn , mix well to obtain an aqueous solution, and use a pH regulator to adjust the pH of the aqueous solution to 3. The aqueous solution with a pH of 3 is firstly filtered through a filter to remove various foreign substances brought in during the weighing and configuration process, and then finely filtered with a 0.22 μm microporous membrane to remove particles and bacteria to obtain a clear liquid, which is obtained after fine filtration liquid medicine. The aseptic filling process is adopted to fill the obtained medicinal liquid into a bottle, and to sterilize the filled bottled oral liquid to kill all the mic...

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Abstract

The invention belongs to the field of medicine healthcare products and particularly relates to a medicine composition for treating osteoarthritis and a preparing technology thereof. The medicine composition for treating osteoarthritis is mainly prepared from, by weight, 20-45 parts of glucosamine and 4-20 parts of taurine. Preferably, the medicine composition is used in the mode that 140-670 weight parts of deionized water are added for supporting an oral liquid preparation; meanwhile, a pH value of oral liquid is 2.0-6.5 preferably. The medicine composition has the advantages of being good in stability, and remarkable in effect of treating osteoarthritis and especially senile osteoarthritis; moreover, the oral liquid preparation provided correspondingly has the above advantages and also has the advantages of reducing gastrointestinal pressure of patients and being easy to take and accept by the patients for a long term.

Description

technical field [0001] The invention belongs to the field of medical and health products, and in particular relates to a pharmaceutical composition for treating osteoarthritis and a preparation process thereof. Background technique [0002] Osteoarthritis is a degenerative disease, which is caused by many factors such as aging, obesity, strain, trauma, congenital abnormalities of joints, joint deformities and other factors. Osteoarthritis, degenerative arthritis, senile arthritis, hypertrophic arthritis, etc. Clinical manifestations include slowly developing joint pain, tenderness, stiffness, joint swelling, limited mobility, and joint deformity. [0003] The treatment methods for osteoarthritis include drug therapy, surgery, physiotherapy, physical therapy and other adjuvant treatments. Among them, drug therapy is the most commonly used treatment method. The drugs used in drug therapy are mainly divided into two types: non-steroidal anti-inflammatory drugs and glucosamin...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K31/7008A61K31/737A61K47/04A61P19/02A61K31/185
CPCA61K9/0053A61K9/08A61K31/185A61K31/7008A61K31/737A61K47/02A61K2300/00
Inventor 陈曼
Owner 北京素维生物科技有限公司
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