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Medicine composition for treating infant spleen deficiency type diarrhea and preparation method thereof

A composition and spleen-deficiency type technology, applied in the directions of drug combinations, pharmaceutical formulations, medical preparations containing active ingredients, etc., can solve the problems of heavy gastrointestinal tract burden, prone to body fluids, toxic and side effects, etc., and achieve the protection of gastrointestinal mucosa, The effect of short treatment course and no toxic side effects

Inactive Publication Date: 2015-11-25
张庆彪
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] Causes of diarrhea in infants and young children: 1. Physical factors: This disease mainly occurs in infants and young children. heavy burden
(2) Nervous, endocrine, circulatory system, liver and kidney functions are immature in infancy, and the regulation function is poor
(3) The baby's immune function is not perfect
(4) The body fluid distribution of infants is different from that of adults. The proportion of extracellular fluid is relatively high, and the water metabolism is vigorous, and the regulation function is poor, so it is more prone to body fluid and electrolyte disorders
(2) intolerance to carbohydrates
(3) Food allergies
(4) Drug influence
[0007] But above-mentioned therapeutic method affects appetite, treats the symptoms but not the root cause, is unfavorable for treatment, and has toxic side effects

Method used

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Experimental program
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Effect test

preparation example Construction

[0068] When the dosage form of the pharmaceutical composition is a capsule, its preparation method comprises the following steps:

[0069] The first step is to mix the raw materials of the pharmaceutical composition in proportion, add ethanol with an alcohol concentration of 85-95% that is 2-4 times the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first Extraction solution; add ethanol with an alcohol concentration of 85-95% relative to the mass of the medicinal residues that is 1-2 times the mass of the medicinal residues obtained by filtering, heat and reflux for 1-3 hours, extract, and filter to obtain a second extraction solution; The first extract and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0070] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 2 hours, pulverized, and sieved to o...

Embodiment 1

[0082] Embodiment 1 capsule

[0083] The preparation process of the capsule of the present invention is as follows: get 160g of gorse root, 280g of calyx, 140g of heterophylla, 300g of amomum, 220g of codonopsis, 150g of Polygonum polycysticum, 130g of licorice, 180g of frangipani laurel, 320g of salvia miltiorrhiza, 320g of forsythia 140g, Cimicifuga 260g, Ligusticum edulis 330g, Dingjingcao 200g, Atractylodes macrocephala 320g, Zernia 160g, Acanthopanax 350g, Scorpio 200g, Guya 140g, Hollyhock leaf yam 250g, Wild poppy 30g, Smilax 350g, Eupatorium 120g, 170g of cloves, 330g of Xu Changqing, 200g of Quercetin, 20g of Wangjiangzi, 130g of Curcuma, 200g of Gorgon, 300g of longum, 250g of Amaranth and 150g of Amaranth;

[0084] The first step is to mix the raw materials of the pharmaceutical composition in proportion, add ethanol with an alcohol concentration of 90% to 3 times the mass of the mixture, heat and reflux for 2 hours, extract, and filter to obtain the first extract; ...

Embodiment 2

[0087] Embodiment 2 Granules

[0088] The preparation process of the granules of the present invention is as follows: get 180g of gorse root, 300g of cayenne, 160g of heterophylla, 250g of amomum, 340g of codonopsis, 200g of Polygonum polycysticum, 300g of licorice, 150g of frangipani laurel, 320g of salvia miltiorrhiza, 320g of forsythia 170g, 250g Cimicifuga, 330g Ligusticum edulis, 160g Dingjingcao, 240g Atractylodes macrocephala, 140g Juema, 330g Acanthopanax, 210g Liga, 160g grain buds, 210g hollyhock leaf yam, 40g wild poppy, 310g smilax, eupatorium 120g, 210g of cloves, 350g of Xu Changqing, 310g of Quercetin, 30g of Wangjiangzi, 150g of Curcuma, 160g of Gorgon, 310g of longum, 240g of Amaranth and 180g of Amaranth;

[0089] The first step is to mix the raw materials of the pharmaceutical composition according to the stated ratio, add 85% ethanol with an alcohol concentration 6 times that of the mixture, heat to boiling and reflux for 4 hours, filter, and use the percol...

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Abstract

The invention discloses a medicine composition for treating infant spleen deficiency type diarrhea and a preparation method thereof. The medicine composition comprises the following raw medicinal materials: Chinese peashrub root , ventilago leiocarpa, radix pseudostellariae, fructus amomi, radix campanumoeae, polygonum polystachyum, radix glycyrrhizae, jasminum laurifolium, radix salviae miltiorrhizae, fructus forsythia, rhizoma cimicifugae, rhizoma ligustici, vandellia cordifolia, rhizoma atractylodis macrocephalae, potentilla anserina, acanthopanax senticosus, thlaspi arvense, fructus setariae germinatus, dioscorea althaeoides, papaver nudicaule, chinaroot greenbier rhizome, herba lycopi, clove, radix cynanchi paniculati, daimyo oak seeds, coffee senna seeds, rhizoma curcumae, semen euryales, fructus piperis longi, lyonia ovalifolia and copperleaf herb. The medicine composition has the benefits of having the efficacies of strengthening spleen, recuperating stomach, benefiting qi, checking diarrhea and aiding digestion, having the effects of protecting gastrointestinal mucous membrane, enhancing resistance and relieving pain, and having the advantages of taking effect quickly, and being high in efficiency, accurate in curative effect, short in treatment course, free of toxic and side effects, low in price, and the like.

Description

technical field [0001] The invention relates to the technical field of pharmaceutical preparations, in particular to a pharmaceutical composition for treating diarrhea of ​​spleen deficiency type in infants and a preparation method thereof. Background technique [0002] Infant diarrhea, also known as infant dyspepsia, is a syndrome of acute gastrointestinal dysfunction in infants and young children, mainly characterized by diarrhea and vomiting, with the highest incidence in summer and autumn. The pathogenic factors of this disease are divided into three aspects: constitution, infection and digestive disorder. The main clinical manifestations are increased stool frequency, loose stools, and water and electrolyte disturbances. If the disease is not treated in time, severe water and electrolyte imbalance may endanger the life of children. [0003] Causes of diarrhea in infants and young children: 1. Physical factors: This disease mainly occurs in infants and young children...

Claims

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Application Information

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IPC IPC(8): A61K36/9066A61P1/12
Inventor 张庆彪孔令禹
Owner 张庆彪
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