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Processing method of gardenia decoction pieces

A technology of gardenia and decoction pieces, applied in the field of traditional Chinese medicine processing, can solve the problems of ineffective retention of active ingredients of gardenia, uneven quality of medicinal gardenia, inconsistent processing technology of gardenia, etc., and achieve the goal of reducing geniposide content Reduce and solve the effect of low geniposide content and save manpower and material resources

Active Publication Date: 2018-05-25
天圣制药集团重庆药物研究院有限公司
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  • Description
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  • Application Information

AI Technical Summary

Problems solved by technology

"Chinese Pharmacopoeia" 2010 edition contains the processing methods of gardenia as follows: gardenia, "remove impurities and crush"; stir-fry gardenia, "take clean gardenia, stir-fry yellow-brown according to the clear frying method"; Gardenia, "Take gardenia, or crush it, fry it with medium heat according to the clear frying method until the surface is burnt brown or black, the inner surface of the peel and the surface of the seeds are yellowish brown or brown, take it out, and let it cool", therefore, its The degree of frying or frying can only be based on experience, and there is no specific criterion for judging it. As a result, the processing technology of gardenias in different places is not uniform, resulting in uneven quality of medicinal gardenias
The content of geniposide in Gardeniae jasminoides after frying yellow, charcoal and charcoal was determined by high performance liquid chromatography. Decreased, and the largest reduction was caused by frying charcoal, indicating that the content of geniposide in Gardenia jasminoides is easily affected by the processing method and temperature, and the processing methods currently used cannot effectively retain the active ingredients in Gardenia jasminoides

Method used

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  • Processing method of gardenia decoction pieces
  • Processing method of gardenia decoction pieces
  • Processing method of gardenia decoction pieces

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0022] The establishment of embodiment 1 geniposide content assay method

[0023] 1 Preparation of reference substance solution

[0024] Take an appropriate amount of geniposide reference substance (purchased from Shanghai Shifeng Biotechnology Co., Ltd.), accurately weighed, add methanol to make a reference substance solution containing 0.168 mg of geniposide per 1 ml, shake well, and filter through a 0.22 μm microporous membrane. Pass, that is.

[0025] 2 Preparation of the test solution

[0026] Take about 0.5g of gardenia medicinal material powder (passed through No. 4 sieve of Pharmacopoeia), accurately weigh it, put it in a stoppered Erlenmeyer flask, accurately add 125m1 of methanol, weigh it, treat it with ultrasound for 20 minutes, let it cool, and weigh it again. Make up the lost weight with methanol, shake well, and filter. Precisely measure 20ml of the continued filtrate, put it in a 50ml measuring bottle, add methanol to the mark, shake well, and you get it.

...

Embodiment 2

[0045] Embodiment 2 The medicine frying machine design with intelligent temperature and humidity control used in the present invention

[0046] Because the temperature control in the process of frying medicine is very important to the geniposide content of gardenia after frying, a medicine frying machine with intelligent temperature and humidity control is specially designed, such as figure 1 , 2As shown, the medicine frying machine includes: a controller 2, a temperature sensor, a humidity sensor, a heater 7 and a boiler 5;

[0047] Put the medicinal materials to be fried inside the boiler 5, install a temperature sensor and a humidity sensor on the boiler 5, the temperature sensor signal output end is connected to the temperature signal receiving end of the controller 2, the humidity sensor signal output end is connected to the controller 2 humidity signal receiving end, and the controller 2 controls The end is connected to the temperature adjustment control end of the heat...

Embodiment 3

[0060] Embodiment 3 gardenia processing technology is established

[0061] The medicine frying machine used in this embodiment is the medicine frying machine with intelligent temperature and humidity control in Example 2.

[0062] 1 Investigation on the characters of Gardenia jasminoides

[0063] Take clean gardenias, dry them, and crush some gardenias. Weigh 100g each of the whole and crushed gardenias, respectively put the gardenias in a hot pot, fry at 180°C for 6 minutes, take them out, and spread them out to dry in time. Taking geniposide as the evaluation index, the influence of the morphology of gardenia jasminoides on the processing of jasmine jasminoides was investigated. The results are shown in Table 3. The results showed that the content of geniposide in the crushed gardenia jasminoides decreased significantly after frying, indicating that the whole gardenia jasminoides was better for processing.

[0064] Table 3 content determination results

[0065]

[0066...

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Abstract

The invention discloses a method for processing gardenia decoction pieces, which is characterized in that it comprises the following steps: 1) taking clean gardenia and drying; 2) putting the dried gardenia into a decoction with intelligent temperature and humidity control In the preheated boiler (5) of the machine, stir-fry at 160-200°C for 6-10 minutes; 3) Take out the fried gardenias and spread them out to dry. The herbal frying machine used in the present invention collects temperature data through a temperature sensor, thereby controlling the heater to fry the medicinal materials through the controller, so that the temperature in the herbal roasting machine is accurately controlled, so that the herbal roasting machine is properly heated, effectively ensuring The content of geniposide in the fried gardenia solves the problem that the content of the geniposide is low after the gardenia is fried.

Description

technical field [0001] The invention belongs to the technical field of processing traditional Chinese medicines, and in particular relates to a method for processing gardenia decoction pieces. Background technique [0002] Gardenia (scientific name: Gardenia jasminoides Ellis) aliases: yellow gardenia, mountain gardenia, white toad, is the fruit of the Rubiaceae plant gardenia. The original plants are mainly distributed in Fujian, Jiangxi, Zhejiang, Hunan, Anhui, Taiwan and other places in China. The fruit of gardenia is a traditional Chinese medicine, which belongs to the first batch of medicinal and edible resources promulgated by the Ministry of Health. In traditional Chinese medicine, it is often used to treat jaundice hepatitis, sprains, high blood pressure, diabetes and other diseases. Gardenia was first recorded in "Shen Nong's Materia Medica". It is cold in nature, slightly sour and bitter in taste, non-toxic, and has the effects of purging fire and relieving restl...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K36/744
Inventor 刘群谈宗华吴统选杨月梅
Owner 天圣制药集团重庆药物研究院有限公司
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