Traditional Chinese medicine for treating kidney-yang deficiency type primary osteoporosis and preparation method

A technology for osteoporosis and kidney-yang deficiency type, applied in the field of pharmacy, can solve the problems of unclear specific mechanism of action, poor long-term safety, large side effects, etc., and achieve the effect of strong pertinence, small side effects, and high efficiency.

Inactive Publication Date: 2015-09-09
林倩
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the above-mentioned drugs have relatively large side effects, poor long-term safety, are expensive, or the specific mechanism of action is unclear, and cannot solve the inevitable problems such as restoring lost bone mass.

Method used

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  • Traditional Chinese medicine for treating kidney-yang deficiency type primary osteoporosis and preparation method

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preparation example Construction

[0044] Wherein, when the dosage form of described Chinese medicine is capsule, its preparation method comprises the following steps:

[0045] The first step is to mix the various raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85-95% relative to the mass of the mixture, heat and reflux for 1-3 hours, extract, and filter to obtain the first extract Adding the obtained dregs by filtration with ethanol with an alcohol concentration of 85-95% relative to the quality of the dregs 1-2 times, heating and refluxing for 1-3 hours, extracting, and filtering to obtain a second extract; The liquid and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0046] In the second step, the dry paste obtained in the first step is placed in an ultrafine pulverizer for 1 to 2 hours, pulverized, and sieved to obtain an ultrafine powder of 300 mesh to 400 me...

Embodiment 1

[0052] Embodiment 1: Capsules

[0053] Take 250g of variegated leaf orchid, 360g of Liedang, 180g of golden ribbon, 120g of silk cotton wood, 240g of samara vine, 210g of Yunnan five flavors, 120g of scissors vine, 180g of sharp medicine flower, 260g of small white cotton, 230g of coix leaf, 160g of halo medicine , Cadida 110g, Erigeron 260g, Acanthopanax 130g, Osmanthus root 210g, Black old man 330g, Gorse 200g and 310g.

[0054] Its preparation method comprises the following steps:

[0055] The first step is to mix the raw materials of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 95% that is three times the mass of the mixture, heat and reflux for 3 hours, extract, and filter to obtain the first extract; filter the obtained dregs Then add ethanol with an alcohol concentration of 95% relative to the quality of the dregs, heat and reflux for 2 hours, extract, and filter to obtain the second extract; combine the first extract and...

Embodiment 2

[0058] Embodiment 2: Granules

[0059] Take 280g of variegated leaf orchid, 390g of Liedang, 160g of golden ribbon, 140g of silk cotton wood, 210g of samara vine, 240g of Yunnan five flavors, 140g of scissors vine, 160g of sharp medicine flower, 280g of small white cotton, 220g of coix leaf, 190g of halo medicine , Cadida 110g, Erigeron breviscapus 280g, Acanthopanax ovalifera 150g, Osmanthus osmanthus root 230g, Black old man 340g, Gorse flower 250g, and 330g of eucalyptus.

[0060] Its preparation method comprises the following steps:

[0061] Step 1: Mix the raw medicinal materials according to the stated ratio, add ethanol with an alcohol concentration 6 times that of the mixture and 90% ethanol, let stand for 38 hours, filter, and slowly percolate at a rate of 2ml per minute by percolation method , collect the percolation liquid, then concentrate under reduced pressure at 0.09Mpa to a paste with a relative density of 1.10 at 60°C, spray dry, the air inlet temperature of ...

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Abstract

The invention provides a traditional Chinese medicine for treating kidney-yang deficiency type primary osteoporosis and a preparation method. The traditional Chinese medicine comprises raw materials as follows: herb of creeping rattlesnake plantain, skyblue broomrape herb, lethariella zahlbruckneria, Euonymus bungeanus, Myriopteron extensum, Yunnan Schisandra rubriflora, Annular Holostemma, Aechmanthera tomentosa Nees, hoary bluebell flower, leaves of Jobstears, Polygonum chinense L., Stachys affinis, herba erigerontis, Aeanthopanax obovatus Hoo, Roots of Artocarpus lingnanensis, gardneria roots, Parochetus communis and pearl flowers. The traditional Chinese medicine has the beneficial effects of high pertinence, little side effect, good curative effect and high significant efficiency.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating primary osteoporosis of kidney-yang deficiency type and a preparation method thereof. Background technique [0002] Osteoporosis (Osteoporosis, OP) is a disease characterized by bone loss and marked structural degeneration of bone tissue (cancellous bone trabeculae are thinned, broken, and reduced in number; cortical bone is porous and thinned), resulting in bone loss. A systemic bone disorder of increased fragility and increased risk of fracture. With the advent of an aging society, osteoporosis has gradually become a worldwide concern. There are two types of osteoporosis: primary and secondary. Primary osteoporosis includes postmenopausal osteoporosis (type I) and senile osteoporosis (type II). With the development of history and the advancement of science and technology, people's understanding of osteoporosis has gradually deepen...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8994A61P19/10
Inventor 林倩李卫新
Owner 林倩
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