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A kind of compound amino acid capsule and preparation method thereof

A compound amino acid and capsule technology, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, anti-toxins, etc., can solve the problems of reducing the physiological activities of amino acids, ginseng and Panax notoginseng, and the occurrence of chemical reactions, so as to improve bioavailability , the ratio is scientific and reasonable, and the effect of easy mass production

Active Publication Date: 2018-06-26
广东生命一号药业股份有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0005] CN103989692A discloses a method for preparing compound amino acid ginsenoside capsules. The compound amino acid and ginsenoside raw materials are fully mixed and evenly dried and sterilized at 100°C, and then packed into capsules to make a finished product. It is convenient to take and has good effect, but various raw materials are mixed together It is easy to cause chemical reactions during storage, and high-temperature drying will reduce the physiological activities of amino acids, ginseng and notoginseng

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0031] The compound amino acid capsule is composed of the following four groups of components in parts by weight:

[0032] (1) Group: 1 part of ginseng extract, 5 parts of Panax notoginseng extract;

[0033] (2) Group: 20 parts of tryptophan;

[0034] (3) Group: 10 parts of leucine, 10 parts of phenylalanine, 20 parts of threonine, 20 parts of valine;

[0035] (4) Group: 30 parts of arginine hydrochloride, 20 parts of histidine hydrochloride, 50 parts of isoleucine, 30 parts of lysine hydrochloride, and 80 parts of methionine.

[0036] The ginseng extract is obtained by reflux extracting ginseng powder in 8 times the amount of 80% ethanol solution twice, each time for 1.5 hours, and then filtering and drying.

[0037] For the Panax notoginseng extract, place the Panax notoginseng powder in 8 times the amount of water, add 30U / g cellulase and 40U / g pectinase, adjust the pH to 4, and enzymolyze it in a water bath at 50°C for 2 hours, After enzymatic hydrolysis, sonicate for 1...

Embodiment 2

[0045] The compound amino acid capsule is composed of the following four groups of components in parts by weight:

[0046] (1) Group: 5 parts of ginseng extract, 1 part of Panax notoginseng extract;

[0047] (2) Group: 30 parts of tryptophan;

[0048] (3) Group: 30 parts of leucine, 20 parts of phenylalanine, 50 parts of threonine, 40 parts of valine;

[0049] (4) Group: 10 parts of arginine hydrochloride, 10 parts of histidine hydrochloride, 20 parts of isoleucine, 10 parts of lysine hydrochloride, 40 parts of methionine.

[0050] The ginseng extract is obtained by reflux extracting ginseng powder in 8 times the amount of 60% ethanol solution for 3 times, each time for 1.5 hours, and then filtering and drying.

[0051] For the Panax notoginseng extract, place the Panax notoginseng powder in 8 times the amount of water, add 20 U / g of cellulase and 60 U / g of pectinase, adjust the pH to 5, and enzymolyze it in a water bath at 60°C for 1 hour, After enzymatic hydrolysis, sonic...

Embodiment 3

[0059] The compound amino acid capsule is composed of the following four groups of components in parts by weight:

[0060] (1) Group: 3 parts of ginseng extract, 3 parts of Panax notoginseng extract;

[0061] (2) Group: 25 parts of tryptophan;

[0062] (3) Group: 20 parts of leucine, 15 parts of phenylalanine, 30 parts of threonine, 30 parts of valine;

[0063] (4) Group: 20 parts of arginine hydrochloride, 15 parts of histidine hydrochloride, 30 parts of isoleucine, 20 parts of lysine hydrochloride, 60 parts of methionine.

[0064] The ginseng extract is obtained by reflux extracting ginseng powder in 8 times the amount of 70% ethanol solution for 3 times, each time for 1 hour, and then filtering and drying.

[0065] The Panax notoginseng extract is prepared by placing the Panax notoginseng powder in 8 times the amount of water, adding 25 U / g of cellulase and 50 U / g of pectinase, adjusting the pH to 4.5, and enzymolyzing it in a water bath at 55°C 1.5h, after enzymatic hyd...

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Abstract

The present invention relates to compound amino acid capsules and a preparation method thereof, and belongs to the technical field of health food preparation. The compound amino acid capsules comprise the following four groups of components that (1) the first group of the components comprises 1-10 parts of a ginseng extract, and 1-10 parts of a panax notoginseng extract; (2) the second group of the components comprises 20-30 parts of tryptophan; (3) the third group of the components comprises 10-30 parts of leucine, 10-20 parts of phenylalanine, 20-50 parts of threonine, and 20-40 parts of valine; and (4) the fourth group of the components comprises 10-30 parts of arginine hydrochloride, 10-20 parts of histidine hydrochloride, 20-50 parts of isoleucine, 10-30 parts of lysine hydrochloride, and 40-80 parts of methionine. The preparation method comprises: respectively adding the four groups of the components into a sugarcoating jar, intermittently spraying an adhesive by using a high pressure spraying gun, continuously rolling the components in the pot and intermittently adding the components to prepare pellets, carrying out pellet selection, drying and coating on the prepared pellets, uniformly mixing, and loading into capsules so as to obtain the finished product. The compound amino acid capsules have characteristics of high active ingredient, strong functionality, stable performance, and convenient oral taking.

Description

technical field [0001] The invention relates to a compound capsule and a preparation method thereof, in particular to a compound amino acid capsule with high active ingredients, strong functionality and stable performance and a preparation method thereof, belonging to the technical field of functional food preparation. Background technique [0002] Protein is the material basis of human life activities. Many functions of the human body, such as immune function, cell damage repair function and growth and development function, are closely related to protein metabolism. Amino acid is the basic unit of tissue protein synthesis and is also used for synthesis An important substrate for many small molecules such as nitric oxide, polyamines, glutathione, creatine, carnitine, thyroid hormones, serotonin, melanin, and heme, with numerous important physiological implications. Amino acids have traditionally been nutritionally divided into essential and non-essential amino acids based on...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/62A61K36/258A61P37/04A61P39/00A61K31/198
Inventor 吕明慧黄界洲
Owner 广东生命一号药业股份有限公司
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