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Bioactive absorbable medical strapping tape and forming method

A technology of biological activity and forming method, which is applied in medical science, surgery, etc., can solve the problems of large compressive stress of metal strapping, small compressive stress of suture strapping, and difficulty in taking out the bundle after secondary surgery, so as to achieve the goal of not being easy to break and crack , the effect of avoiding osteoporosis, good biocompatibility and controllable degradation

Inactive Publication Date: 2015-05-20
深圳市博立生物材料有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

The compressive stress of the suture strap is small, the fracture fixation is unstable, and it is not conducive to fracture healing
In addition, when the steel wire is wrapped by bone, it is very difficult to remove it in the second operation.
The disadvantage of silk thread is that it is not strong enough, so it is only used for small bone fragments or auxiliary fixation, and most of them need external fixation protection
[0005] Memory alloy embracing devices have achieved good results in fracture fixation, but nickel in its constituent elements is the most common contact metal allergen and has a clear carcinogenic effect
It has obvious advantages for femoral fractures during and after artificial total hip replacement, as well as other strapping fixation, but the metal strapping has too much compressive stress, which is easy to cause stress shielding, which is not conducive to fracture healing

Method used

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  • Bioactive absorbable medical strapping tape and forming method
  • Bioactive absorbable medical strapping tape and forming method
  • Bioactive absorbable medical strapping tape and forming method

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0060] Bioactive absorbable medical strapping: made of polylactic acid (PLA) and hydroxyapatite (HA), the molecular weight of polylactic acid (PLA) is 100,000-200,000, and the particle size of hydroxyapatite (HA) is 0.5 μm, in terms of weight percentage, the total amount of polylactic acid (PLA) accounts for 90% of the total weight of the composite material, and hydroxyapatite (HA) accounts for 10% of the total weight of the composite material.

[0061] The forming method of the above-mentioned bioactive absorbable medical bandage comprises the following steps:

[0062] (1) Take an appropriate amount of polylactic acid (PLA) and hydroxyapatite (HA) according to the weight percentage;

[0063] (2) The obtained material is obtained by a liquid phase adsorption method to obtain a uniformly dispersed composite material;

[0064] (3) After the composite material is thermally plasticized at 80° C., the strapping belt with the desired shape and structure is produced by a stamping an...

Embodiment 2

[0068] Bioactive absorbable medical strapping tape: made of polylactic acid-glycolic acid copolymer (PLGA), polyglycolic acid (PGA), and β-tricalcium phosphate porous ceramics (β-TCP), polylactic acid-hydroxy The molecular weight of acetic acid copolymer (PLGA) and polyglycolic acid (PGA) is 800,000-1,500,000, and the particle size of β-tricalcium phosphate porous ceramic (β-TCP) is 10-13 μm. According to weight percentage, polylactic acid-glycolic acid The total amount of copolymer (PLGA) and polyglycolic acid (PGA) accounts for 70% of the total weight of the composite material, and the β-tricalcium phosphate porous ceramic (β-TCP) accounts for 30% of the total weight of the composite material.

[0069] The forming method of the above-mentioned bioactive absorbable medical bandage comprises the following steps:

[0070] (1) Take an appropriate amount of the polylactic acid-glycolic acid copolymer (PLGA), polyglycolic acid (PGA) and β-tricalcium phosphate porous ceramics (β-TC...

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Abstract

The invention relates to the field of bio-medical instruments, and in particular relates to a bioactive absorbable medical strapping tape and a forming method. The bioactive absorbable medical strapping tape is prepared by combining a biological absorbable high polymer material and bioactive ceramic or bioactive glass, wherein in percentages by weight, the biological absorbable high polymer material accounts for 70-95% of the total weight of the composite material and the bioactive ceramic or bioactive glass accounts for 5-30% of the total weight of the composite material; the biological absorbable high polymer material is selected from any one or more of polylactic acid, polycaprolactone, a polylactic acid-glycolic acid copolymer, polyglycolic acid, polyhydroxyalkanoate and polyhydroxybutyrate, and the molecular weight is 100,000-2,000,000. The medical strapping tape not only can achieve expected physical properties, mechanical properties, degradation rate, biocompatibility and osteogenesis effect, but also can relieve stress shielding, accelerate fracture healing and avoid second operation.

Description

technical field [0001] The invention relates to the field of biomedical devices, in particular to a bioactive absorbable medical strapping and a molding method. Background technique [0002] With the advent of an aging society, senile bone and joint disease has become the main disease in human society next to cardiovascular disease, and the corresponding hip and knee replacement operations have increased rapidly; at the same time, the number of patients with osteoporosis And the resulting harm has also become a common problem faced by patients and doctors. The elderly are prone to intraoperative or postoperative fractures during hip arthroplasty, and upper femur binding and fixation are the main measures for the treatment and prevention of femoral splitting during total hip surgery. [0003] The most widely used binding device is mainly a metal strap. In addition, metal straps are also widely used in the preventive strapping of osteoporotic fractures and the treatment of o...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61L31/14A61L31/02A61L31/06A61L31/16
Inventor 张平宋小文谢婷婷
Owner 深圳市博立生物材料有限公司
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