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Traditional Chinese medicine for treating cervical cancer caused by damp heat and phlegm retention and preparation method of traditional Chinese medicine

A technology for cervical cancer, damp-heat stasis, applied in pharmaceutical formulations, medical preparations containing active ingredients, drug delivery, etc., can solve problems such as acute chemical pneumonia, heart failure, respiratory failure, etc. Highly targeted and low recurrence rate

Inactive Publication Date: 2015-03-25
鲁娟
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0014] 4. Some chemotherapeutic drugs have toxic effects on the cardiovascular system, and heart failure may occur in severe cases
[0015] 5. Chemotherapy drugs that have toxic effects and adverse reactions on the respiratory system can cause acute chemical pneumonia and chronic pulmonary fibrosis, and even respiratory failure
[0017] 7. Some drugs can affect fertility and cause teratogenicity

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0067] When the dosage form of any one of the above-mentioned Chinese medicines is a powder, its preparation method may further comprise the steps:

[0068] In the first step, mix ascites grass, millennium buluxin, tomb head back, zedoary, chrysanthemum, Scutellaria barbata and Coptis chinensis according to the stated ratio, and use an alcohol concentration 3 to 5 times the mass of the obtained mixture as Dissolve in 85%-95% ethanol, heat and reflux for 2-4 hours, extract, filter to obtain the first filtrate; filter the residue again with alcohol concentration 85%-95% of 1-2 times the mass of the obtained mixture Dissolve in ethanol, heat and reflux for 1 to 2 hours, extract, filter to obtain the second filtrate; combine the first and second filtrates, recover the ethanol under reduced pressure and concentrate until the concentration of the medicinal solution is 0.7 to 0.9 g crude drug / mL, After elution with a macroporous adsorption resin column with a volume of 5 L, first elu...

Embodiment 1

[0080] Embodiment 1: Powder

[0081] Take 340g of ascites grass, 130g of millennium not dead heart, 490g of tomb head, 290g of curcuma, 110g of yellow solitary seeds, 180g of banzhilian, 210g of coptis, 360g of dandelion, 230g of phoenix grass, 60g of saikui, 120g of white horse bone, and cleavage 150g, 240g Malan, 190g Dirtgrass, 220g Xiaofei Peng, 110g Twister, 220g Purslane, 280g Kylin Tail, 130g Dajindao, 60g Huangguo Eggplant, 160g Chrysanthemum and 230g Yellow Earwort;

[0082] Its preparation method comprises the following steps:

[0083] In the first step, mix Ascites Herbs, Millennium Buluishin, Tombhead Hui, Curcuma, Rhododendron Radix, Scutellaria Scutellariae and Coptidis Rhizome according to the stated ratio, and use an alcohol concentration of 4 times the mass of the obtained mixture to be 90% Dissolve in ethanol, extract after heating and reflux for 4 hours, filter to obtain the first filtrate; dissolve the filter residue with ethanol with an alcohol concentrat...

Embodiment 2

[0087] Embodiment 2: oral liquid

[0088]Take 320g of ascites grass, 120g of millennium not dead heart, 460g of tomb head, 270g of curcuma, 130g of yellow solitary seeds, 160g of barbata, 220g of coptis, 380g of dandelion, 21 of fern grass, 90g of saikui, 130g of white horse bone, and clematis 170g, 220g Malan, 160g Dirtgrass, 250g Xiaofei Peng, 130g Twister, 240g Purslane, 260g Kylin Tail, 150g Dajindao, 80g Huangguo Eggplant, 170g Chrysanthemum and 210g Yellow Earwort;

[0089] Its preparation method comprises the following steps:

[0090] The first step is to mix ascites grass, millennium not dead heart, tomb head back, curcuma, Huangdulingyuzi, Scutellaria barbata, Coptis chinensis, Dandelion, Phoenix tail grass, Saikui and white horse bone, add 5 times the amount of alcohol relative to the mixture Reflux extraction with 85% ethanol for 3 times, each time for 2 hours, filter, combine the filtrates, recover ethanol, concentrate to a paste with a relative density of 1.30 at...

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PUM

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Abstract

The invention provides a traditional Chinese medicine for treating a cervical cancer caused by damp heat and phlegm retention and a preparation method of the traditional Chinese medicine. The traditional Chinese medicine comprises the following raw herbal materials: veronicastrum herb, solanum dulcamara, patrinia heterophylla, curcuma zedoary, air potato bulblet, sculellaria barbata, coptis chinensis, dandelion, phoenix-tail fern, malvastrum coromandelianum, serissa serissoides, narrow-leaved lindernia, indian kalimeris herb, hypericum japonicum, horseweed herb, jasminum elongatum, herba portulacae, epipremum pinnatum, ovate neolepisorus herb, solanum xanthocarpum, creeping dichondra and goldhair hedyotis herb. The traditional Chinese medicine has the beneficial effects that according to the principle of syndrome differentiation depending treatment of the traditional Chinese medicine, the traditional Chinese medicine has high pertinence on the cervical cancer caused by damp heat and phlegm retention, has the advantages of accurate curative effect, small toxic and side effects, and low recurrence rate, and is fast in acting.

Description

technical field [0001] The invention relates to a medical preparation containing components derived from plants, animals or minerals, in particular to a traditional Chinese medicine for treating damp-heat stasis type cervical cancer and a preparation method thereof. Background technique [0002] Cervical cancer refers to malignant tumors that occur in the uterine vagina and cervical canal. Cervical cancer metastasis can spread directly to adjacent tissues and organs, down to the vaginal fornix and vaginal wall, up to the uterus, to both sides of the pelvic cavity, forward to the bladder, and backward to the rectum. It can also be transferred to paracervix, internal iliac, external iliac, and inguinal lymph nodes through lymphatic vessels, and can even be transferred to supraclavicular and other lymph nodes in the whole body in the late stage. Hematogenous metastasis is relatively rare, and the common metastatic sites are lung, liver and bone. Cervical cancer is one of the ...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9066A61P35/00
CPCA61K9/0053A61K9/08A61K9/14A61K36/11A61K36/185A61K36/28A61K36/288A61K36/39A61K36/48A61K36/539A61K36/63A61K36/718A61K36/74A61K36/748A61K36/80A61K36/81A61K36/888A61K36/8945A61K36/9066A61K2236/333A61K2236/39A61K2236/51A61K2236/53A61K2300/00
Inventor 鲁娟刘宏
Owner 鲁娟
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