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Traditional Chinese medicine effervescent tablet for treating respiratory diseases and preparation method of traditional Chinese medicine effervescent tablet

A technology for respiratory tract and effervescent tablets, which can be applied to respiratory diseases, pharmaceutical formulations, medical preparations containing active ingredients, etc., and can solve problems such as inability to fully satisfy clinical medication, patient carrying, inconvenient taking, and large economic burden for patients. To achieve significant curative effect, fast drug dissolution and high bioavailability

Inactive Publication Date: 2014-12-24
武汉科德中医医院有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0003] At present, there is a lack of medicines for the treatment of respiratory diseases caused by environmental pollution in clinical practice, which causes a great economic burden to patients, and the existing pharmaceutical dosage forms are single, mainly syrups and granules, which cause inconvenience for patients to carry and take. , unable to fully meet the needs of clinical medication

Method used

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  • Traditional Chinese medicine effervescent tablet for treating respiratory diseases and preparation method of traditional Chinese medicine effervescent tablet
  • Traditional Chinese medicine effervescent tablet for treating respiratory diseases and preparation method of traditional Chinese medicine effervescent tablet
  • Traditional Chinese medicine effervescent tablet for treating respiratory diseases and preparation method of traditional Chinese medicine effervescent tablet

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0027] A traditional Chinese medicine effervescent tablet for treating respiratory diseases, which is composed of the following ingredients in weight proportions:

[0028]

[0029] The extracts of lily, platycodon, and licorice are water extracts of lily, platycodon, and licorice. , Platycodon grandiflorum, and licorice are boiled 3 times with water for 1.5 hours each time, combined with the decocting liquid, concentrated into extract, dried and pulverized.

[0030] The acid agent is tartaric acid.

[0031] The alkali agent is sodium bicarbonate.

[0032] The filler is lactose.

[0033] The surfactant was sodium lauryl sulfate.

[0034] The binder was povidone K30.

[0035] The sweetener is aspartame.

[0036] The lubricant was polyethylene glycol 6000.

[0037] The preparation method is as follows: the extracts of lily, platycodon, and licorice are dried and pulverized into fine powder with a particle size of 100 meshes (referring to the fine powder that can pass thr...

Embodiment 2

[0045] A traditional Chinese medicine effervescent tablet for treating respiratory diseases, which is composed of the following ingredients in weight proportions:

[0046]

[0047] The extracts of lily, platycodon, and licorice are water extracts of lily, platycodon, and licorice. , Platycodon grandiflorum, and licorice were decocted twice with water for 2 hours each time. Combine the decoction liquid and concentrate it into a clear paste with a relative density of 1.08. Add ethanol to the clear paste to make the alcohol content 50%. After stirring, let it stand for 24 minutes. hours, the supernatant was concentrated into extract, dried and pulverized.

[0048] The preparation method is as follows: the extracts of lily, Platycodon grandiflorum and licorice are dried and then pulverized into fine powder, and the dry powder of citric acid, 60% sodium bicarbonate, sucrose powder, sodium lauryl sulfate and stevioside is added, and the mixture is evenly mixed; After dissolving ...

Embodiment 3

[0053] A traditional Chinese medicine effervescent tablet for treating respiratory diseases, which is composed of the following ingredients in weight proportions:

[0054]

[0055] The extracts of lily, platycodon, and licorice are water extracts of lily, platycodon, and licorice, and the weight ratio of lily, platycodon, and licorice is 5:4:2 in turn, and extracted according to the conventional water decocting method.

[0056] The preparation method is as follows: the extracts of lily, platycodon and licorice are dried and then pulverized into fine powder, and the dry powders of tartaric acid, 80% sodium bicarbonate, lactose, sodium lauryl sulfate and protein sugar are added and mixed evenly; Bomb was dissolved in absolute ethanol and added to the above powder, mixed and granulated, added polyethylene glycol 6000 and the remaining 20% ​​sodium carbonate to the granules, mixed and pressed into a ring-shaped tablet with a specification of 0.7g .

[0057] Tested: the disintegr...

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Abstract

The invention provides a traditional Chinese medicine effervescent tablet for treating respiratory diseases. The traditional Chinese medicine effervescent tablet consists of the following components such as extract of lily, platycodon grandiflorum and glycyrrhiza uralensis, an acid agent, an alkaline agent, a filling agent, a surfactant, a binder, a sweetening agent and a lubricant. The invention further provides a method of preparing the traditional Chinese medicine effervescent tablet. The preparation method comprises the following steps: drying and crushing the extract of lily, platycodon grandiflorum and glycyrrhiza uralensis into fine powder; adding dry powder of the acid agent, 60-80% of alkaline agent, the filling agent, the surfactant and the sweetening agent to the fine powder, and uniformly mixing; and dissolving the binder with absolute ethyl alcohol and then adding the mixture into the powder to uniformly mix and pelletize, adding the lubricant and the rest of the alkaline agent into the particles, and tabletting after uniformly mixing the components to form the traditional Chinese medicine effervescent tablet. The traditional Chinese medicine effervescent tablet has the functions of removing heat from the lung to relieve cough and dredging lung qi, is suitable for treating various respiratory diseases, and especially suitable for relieving symptoms such as throat discomfort, dry throat, pharyngalgia, nasal obstruction, rhinocnesmus, cough or dry cough, hoarseness, chest distress and asthma, which are caused by air pollution such as haze.

Description

technical field [0001] The invention relates to a traditional Chinese medicine preparation, in particular to a traditional Chinese medicine effervescent tablet for treating respiratory diseases, and a preparation method thereof. Background technique [0002] With the acceleration of urbanization and industrialization, air quality is gradually deteriorating, and the frequency of haze weather is becoming more and more frequent. In this weather, when people travel or work and live, tiny particles ( Mainly refers to particulate matter with a diameter of less than or equal to 2.5 microns, namely PM2.5, also known as lung-penetrable particulate matter) will invade the human respiratory tract and lung lobes when people are unprepared, causing respiratory diseases, especially causing haze. Respiratory system diseases, such as pharyngitis, allergies, asthma, rhinitis, sinusitis, emphysema, etc Symptoms, long-term exposure to this environment can also induce lung cancer, myocardial i...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/8967A61K9/46A61P11/14A61P11/04A61P11/02A61P11/00
Inventor 张德忠孙超
Owner 武汉科德中医医院有限公司
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