Toughening and molding aids for the preparation of starch-based hard capsules and their use

Abstract

The invention relates to a toughening forming auxiliary of a hard capsule taking starch as a matrix for food, healthcare products, medicines and the like, and a starch hard capsule for the food, healthcare products, medicines and the like, prepared from the toughening forming auxiliary of a hard capsule taking starch as a matrix in combination with a starch matrix. The toughening forming auxiliary for preparing a hard capsule taking starch as a matrix consists of 5-50wt% of carrageenan and 50-95wt% of ghatti gum. According to the toughening forming auxiliary provided by the invention, the toughening forming auxiliary is added into the starch matrix, so that the glue-dip forming is assisted by the gelation effect of the carrageenan, and a final capsule shell is toughened by the net structure generated in gelation and a natural polysaccharide carbohydrate chain structure in the ghatti gum; meanwhile, the disintegration of the hard capsule can be effectively promoted by the good solubility and emulsifiability of the ghatti gum, thus the prepared starch hard capsule has excellent flexibility and can be quickly disintegrated.

Description

technical field [0001] The present invention relates to the toughening forming auxiliary agent of the hard capsule with starch as the base used in food, health care product and medicine etc. Starch hard capsules for food, health products and medicines. Background technique [0002] Capsules made from animal-derived gelatin have been around for at least 200 years. Since gelatin can mask the bad taste, smell or irritation to the stomach of many medicines, gelatin capsules are quickly promoted and used in the production of various solid preparations. Over the past 100 years, various capsules made of gelatin have been sold well in the international pharmaceutical market for a long time. At the end of the last century, the outbreak of mad cow disease finally dragged gelatin capsules into an unprecedented crisis of confidence. In April 2012, the "poisonous capsule" incident that broke out in my country undoubtedly aggravated the distrust of the Chinese people towards gelatin ca...

AI Technical Summary

Problems solved by technology

Although the price of hydroxypropyl methylcellulose is not very expensive, the disintegration time of hard capsules prepared with it as the main raw material is relatively long, so its current market share is not high

The price of starch is very low, and it is very attractive to prepare hard capsules. Many domestic manufacturers have also applied for patents for starch capsules. However, because starch molecules are easy to form strong hydrogen bonds, the starch film is brittle and fragile, and it is difficult to produce starch capsules. Produces strong, filling-resistant hard capsules

In recent years, some patents applied by the United States and Japan have prepared a hard capsule shell with high strength by adding a large amount of high-strength gel to the starch matrix, but at the same time it also makes the hard capsule shell difficult to disintegrate, and it is difficult to obtain it in the body. rapidly disintegrating product

Therefore, although there are many patents about hard capsules, it is difficult to form products that can be pushed to the market