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Softgel containing bezoar, snake gall and tendril-leaved fritillary bulb

A technology of bezoar snake gallbladder and soft capsules, which is applied in capsule delivery, plant raw materials, material separation, etc., can solve the problems of unstable ingredients, high cost, and large difference in filling volume, and achieve convenience in taking, small difference in filling volume, and stable properties Effect

Inactive Publication Date: 2013-12-18
杨文龙
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the drop pills have the disadvantages of unstable ingredients, large differences in loading, and high cost.

Method used

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  • Softgel containing bezoar, snake gall and tendril-leaved fritillary bulb
  • Softgel containing bezoar, snake gall and tendril-leaved fritillary bulb
  • Softgel containing bezoar, snake gall and tendril-leaved fritillary bulb

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0080] Bezoar Shedan Chuanbei soft capsule of the present invention is made of the following raw materials:

[0081] Artificial bezoar 2g, Chuan Fritillaria 50g, snake bile 8g, menthol 0.1g, glycerin 20g, gelatin 10g, water 30g, polyethylene glycol 400 (PEG400) 120g.

[0082] Preparation method:

[0083] Take the artificial bezoar and grind it, soak it with 2 times the amount of ethanol for 12 hours, filter it, and make the artificial bezoar extract;

[0084] Chuan Fritillaria is crushed into coarse powder, operated according to the percolation method (Appendix I O of Chinese Pharmacopoeia 2000 edition) under the liquid extract and the extract item, with 50-95% ethanol as solvent, slowly percolating, and receiving the percolating liquid ;

[0085] Combine the ethanol extracts of snake bile, artificial bezoar and Fritillaria chinensis, recover ethanol under reduced pressure (65°C, -0.08MPa), and continue to concentrate under reduced pressure (65°C, -0.16MPa) to a relative den...

Embodiment 2

[0095] Bezoar Shedan Chuanbei soft capsule of the present invention is made of the following raw materials:

[0096] Artificial bezoar 30g, Chuan Fritillaria 800g, snake bile 200g, menthol 5g, glycerin 120g, gelatin 200g, water 200g, polyethylene glycol 400 (PEG400) 300g.

[0097] Preparation method:

[0098] Take the artificial bezoar and grind it, soak it with 10 times the amount of ethanol for 36 hours, filter it, and make the artificial bezoar extract;

[0099] Chuan Fritillaria is pulverized into coarse powder, operates according to the percolation method (Appendix 10 of Chinese Pharmacopoeia 2000 edition) under the liquid extract and extract item, uses 95% ethanol as solvent, slowly percolates, and receives the percolation liquid;

[0100] Combine the ethanol extracts of snake bile, artificial bezoar and Fritillaria chinensis, recover ethanol under reduced pressure (75°C, -0.08MPa), and continue to concentrate under reduced pressure (75°C, -0.08MPa) to a relative densit...

Embodiment 3

[0110] Bezoar Shedan Chuanbei soft capsule of the present invention is made of the following raw materials:

[0111] Artificial bezoar 16g, Chuan Fritillaria 484g, snake bile 81g, menthol 0.4g, glycerin 40g, gelatin 100g, water 90g, polyethylene glycol 400 (PEG400) 150g.

[0112] Preparation method:

[0113] Take the artificial bezoar and grind it, soak it with 5 times the amount of ethanol for 24 hours, filter it, and make the artificial bezoar extract;

[0114] Chuan Fritillaria is crushed into coarse powder, operated according to the percolation method (Appendix I O of Chinese Pharmacopoeia 2000 edition) under the liquid extract and the extract item, with 50-95% ethanol as solvent, slowly percolating, and receiving the percolating liquid ;

[0115] Combine the ethanol extracts of snake bile, artificial bezoar and Fritillaria chinensis, recover ethanol under reduced pressure (60°C, -0.08MPa), and continue to concentrate under reduced pressure (60°C, -0.08MPa) to a relative...

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Abstract

Belonging to the technical field of traditional Chinese medicine, the invention specifically discloses a softgel containing bezoar, snake gall and tendril-leaved fritillary bulb. The Softgel us prepared from the following raw materials by weight: 2-30 g of artificial bezoar, 50-800 g of tendril-leaved fritillary bulb, 8-200g of snake gall, 0.1-5 g of menthol, 20-120 g of glycerol, 10-200 g of gelatin, 30-200 g of water and 120-300 g of polyethylene glycol 400 (PEG400). The softgel can clear heat, reduce phlegm, relieve cough, cure phlegm-heat cough and sticky sputum cough in exogenous cough, and effectively reach the purposes of safety, effectiveness and controllability. Compared with the prior art, the invention provides a safer and more effective clinic capsule form.

Description

technical field [0001] The invention belongs to the technical field of traditional Chinese medicine pharmacy, and in particular relates to Niuhuang Shedan Chuanbei soft capsule and a preparation process thereof. Background technique [0002] Cough is one of the common symptoms of pulmonary diseases, which was first recorded in "Internal Classics". According to traditional Chinese medicine, a cough is caused by exogenous pathogens invading the lungs or visceral dysfunction, resulting in the failure of the lungs to ventilate and descend, and the lung qi to rise upward. From the perspective of modern medical theory, coughing is an important defense mechanism, which can clear the viscous secretions in the pharynx and the entire respiratory tract, as well as inhaled harmful substances and foreign bodies. Physiologically, the clearing effect of cough on the airway is beneficial in the case of excessive secretions, and frequent and severe cough will affect the patient's breathing ...

Claims

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Application Information

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IPC IPC(8): A61K36/8966A61K47/42A61K9/48A61P29/00A61P11/10A61P11/14A61P31/12A61P31/16A61P11/06A61P37/04G01N30/90G01N21/31
Inventor 杨文龙
Owner 杨文龙
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