Molluscicide LDS sustained-release granules and preparation method thereof
A technology of chlorinated salicylamine and slow-release granules, which is applied in the field of pesticides, can solve the problems of repeated application, powder scattering, powder easy to flow with the wind, etc., achieve sustained and slow release of drug effect, strong resistance to rain erosion , increase the effect of killing snails
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Embodiment 1
[0018] Mix 50.0g of chlorosalicylamine technical material, 30.0g of soluble starch, 10g of dextrin, 8.5g of magnesium stearate, 0.6g of sodium laurylsulfonate, and 0.9g of simethicone, and add an appropriate amount of water , while heating to 60°C-70°C, use a mixer to assist stirring evenly, then extrude and granulate, dry and grind until the particle fineness passes the pharmacopoeia sieve of 10 mesh and 24 mesh, and the particle size is 10 mesh to 24 mesh The granules are salicylamine chloride sustained-release granule products.
Embodiment 2
[0020] 50.0g of salicylamine chloride, 30.0g of amylose, 8.5g of sodium carboxymethyl starch, 0.9g of cetyltrimethylsodium bromide, 0.6g of polyoxypropylene polyoxyethylene glyceryl ether, hard Magnesium fatty acid 10.0g, mix evenly, add appropriate amount of water, stir and heat to 70°C, keep for 30 minutes, after becoming a viscous wet mass, extrude and granulate, dry and pass through a pharmacopoeia sieve, take 10 mesh and 24 mesh The granules in between are chlorinated salicylamine sustained-release granules.
Embodiment 3
[0022] With 40.0g salicylamine chloride, 40.0g amylose, 7.0g diatomaceous earth, 10.0g hydroxypropyl methylcellulose, 0.6g cetyltrimethylammonium chloride, 1.5g liquid paraffin, two Mix 0.9g of methyl silicone oil evenly, add appropriate amount of water, and heat to 70-80°C, stir to make it into a viscous mass, extrude and granulate, dry, pass through a pharmacopoeia sieve, and take between 10 mesh and 24 mesh The granules are chlorinated salicylamine sustained-release granules.
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