Obstetric canal lubrication composition

Abstract

The invention provides an obstetric canal lubrication composition for natural childbirth. The composition comprises hydroxyethyl cellulose, a wetting agent and water. The the composition comprises 2.0-8.0wt% of hydroxyethyl cellulose, 15.0-35.0wt% of the wetting agent and the balance of water. The obstetric canal lubrication composition is sterile and has no stimulation, no sensitization, no embryotoxicity and good biocompatibility. The obstetric canal lubrication composition is applied to natural childbirth, times for first and second birth processes are can be shortened, and risks and hurts in a delivery process can be lowered.

Description

technical field [0001] The present invention relates to a composition for lubrication of the birth canal, which can be administered during natural childbirth. Background technique [0002] Childbirth is the period and process in which the fetus separates from the mother's body and exists as a separate entity. The natural delivery of the fetus through the birth canal is an extremely complicated process, which is usually accompanied by severe pain and different degrees of delivery injuries, especially for primiparous women. Therefore, assisted delivery has become the most necessary and most difficult and challenging work in the medical field. [0003] The natural delivery of the fetus involves three main factors: childbirth, birth canal, and labor force. The childbirth includes the fetus, amniotic membrane, and placenta, etc. The birth canal is composed of two parts: the bony birth canal and the soft birth canal, and the labor force mainly comes from uterine contractions and ...

AI Technical Summary

Problems solved by technology

[0005] 1) Forceps assisted delivery: the traction is accurate, the force is reliable, and the delivery can be ended quickly. However, because the forceps occupy a certain space in the birth canal, it will not only cause certain damage to the birth canal (especially the soft part of the birth canal), but may also cause fetal death. Facial injury, facial nerve paralysis, etc.;

[0006] 2) Midwifery with fetal head suction: Compared with forceps midwifery, there is less damage to the birth canal and fetal face, but there is usually a high risk of fetal head hematoma at the suction site. May cause damage to the fetal scalp;

However, the components of the composition are complex and the preparation process is cumbersome. The most serious thing is that the core element component a) polyacrylic acid in the composition is very sensitive to ions in the environment, resulting in strict control during production, storage and application. Conductivity is used to ensure its stable performance, which not only puts forward almost harsh requirements for production, but also brings certain risks and unstable factors to storage and application. For example, in order to ensure the basic isotonic characteristics of its osmotic pressure, implement For example, a large amount of sodium chloride, an ionic isotonic regulator incompatible with a) polyacrylic acid, is used in each prescription, and such an amount of isotonic regulator is enough to seriously affect the rheological properties of a) in the composition (Xiong Jiajia Carbomer gel rheological properties and its influencing factors have been studied in detail), resulting in the need to greatly increase the amount of elements a) and b), and element a) polyacrylic acid polymer materials are usually harmful to the eye , skin and mucous membrane tissue have certain irritation, in addition, polyacrylic polymer material, such as the safety evaluation result of carbomer 934P is oral toxicity is low (the safety evaluation result of hydroxyethyl cellulose is non-toxic), like this It brings huge security risks to the application process.

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