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Traditional Chinese medicine for treating postpartum lochiorrhea and preparation method

A technology of continuous postpartum lochia and traditional Chinese medicine, applied in the field of pharmacy, can solve problems such as adverse reactions and unsatisfactory treatment effects, achieve the effects of no toxic side effects, improve microcirculation, and clear uterine stasis

Inactive Publication Date: 2012-12-26
张梅
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

In terms of treatment, Western medicine generally uses accelerated uterine contractions to stop bleeding, and blood enrichment, followed by antibiotics to control infection, etc. After treatment, symptoms can be relieved, but there are certain adverse reactions, and the treatment effect is not ideal

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0045] The present invention also provides a preparation method of the above-mentioned traditional Chinese medicine, if the prepared dosage form is a tablet, it includes the following steps:

[0046] The first step is to mix the components of the traditional Chinese medicine in proportion, add ethanol with an alcohol concentration of 85% to 95% relative to the mass of the mixture, heat and reflux for 1 to 3 hours, extract, and filter to obtain the first extract , adding ethanol with an alcohol concentration of 85% to 95% relative to the quality of the medicinal residues that is 1 to 2 times the mass of the medicinal residues obtained by filtering, heating and refluxing for 1 to 3 hours, extracting, filtering to obtain a second extract, and extracting the first extract The liquid and the second extract are combined, concentrated under reduced pressure to remove the ethanol solvent, and dried to obtain a dry paste;

[0047] In the second step, the dry paste obtained in the first...

Embodiment 1

[0058] Example 1 Tablet 1

[0059] 19g of mallow fruit, 22g of fennel, 22g of poria cocos, 52g of angelica, 38g of longan meat, 26g of Spatholobus yunnanensis, 24g of twig fruit, 32g of Eucommia ulmoides, 23g of mulberry, 27g of black sesame, 36g of Selaginella, 25g of curcuma, and leaves of arborvitae 30g, sumac 21g, ginseng 77g, astragalus 56g, licorice 36g, dried ginger 17g, Cyperus cyperi 22g, tangerine peel 28g, hawthorn 21g, radish seed 15g, add 2000g of ethanol with an alcohol concentration of 90%, heat and reflux for 3 hours, extract , filter to obtain the first extract, add 300 g of ethanol with an alcohol concentration of 90% to the dregs obtained by filtration, heat and reflux for 2 hours, extract, filter to obtain the second extract, combine the first extract and the second extract, Concentrate under reduced pressure to remove the ethanol solvent, dry to obtain a dry paste, place the obtained dry paste in an ultrafine pulverizer for 2 hours, pulverize, and sieve to...

Embodiment 2

[0060] Embodiment 2 toxicity test

[0061] 60 NIH mice, SPF grade, half male and half male, weighing 18-22 g, were used for the acute toxicity experiment. Mice are divided into two groups at random, i.e. control group and administration group, fasting 12 hours before the experiment, the Chinese medicine tablet prepared by the embodiment of the present invention 1 is dissolved in water, (concentration is 6.28g crude drug / ml, the highest concentration ) gavage, the volume of gavage is 5ml / kg (that is, the single administration dose is 31.4g crude drug / kg), the control group is given isoxan normal saline, 1 day of administration 2 times, the administration interval is 6 hours, and the administration Afterwards, the mice were continuously observed for 14 days, and the number of toxic reactions and deaths of the mice was recorded. The results of the experiment showed that compared with the control group, there was no significant difference in the mice after administration. After 1...

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Abstract

The invention provides a traditional Chinese medicine for treating postpartum lochiorrhea and a preparation method. The traditional Chinese medicine for treating the postpartum lochiorrhea comprises cluster mallow fruit, pulverized yam rhizome, tuckahoe, angelica, arillus longan, caulis kadsurae, entada phaseoloides, eucommia bark, mulberry, black sesame seed, selaginella tamariscina, rhizoma zedoariae, Chinese arborvitae twig, logwood, ginseng, astragalus root, licorice, rhizoma zingiberis, rhizoma cyperi, tangerine peel, hawthorn and semen raphani. The traditional Chinese medicine provided by the invention has the advantages of quickness in acting, strong action, short treatment course, high safety, no obvious toxic or side effect and simple administration, can be used for improving themicrocirculation and promoting the contraction of the uterine smooth muscles, is beneficial to the update of the endometrium and the recession of inflammation and can also be used for automatically discharging the placenta and the fetal membrane which remain in the uterus so as to remove the stasis of the uterine cavity.

Description

technical field [0001] The invention relates to the technical field of pharmacy, in particular to a traditional Chinese medicine for treating postpartum persistent lochia. Background technique [0002] Lochia refers to the dark red liquid discharged from the vagina after childbirth, which contains blood, necrotic decidual tissue, bacteria and mucus. Because the change reflects the involution of the uterus, the problem of lochia is more important in the postpartum health care of the puerpera itself. Normal lochia has a bloody smell, but it is not smelly, and under normal circumstances, it will be clean about 3 weeks after delivery. If it is still dripping and unclean for more than 3 weeks, it is postpartum lochia. [0003] Postpartum lochia is not always the result of poor uterine involution and residual placental membranes in the uterus. There are many influencing factors. The main reasons may be that the cervix is ​​not dilated before operation, which affects the discharg...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61K9/14A61K9/20A61K9/48A61P15/00
Inventor 张梅
Owner 张梅
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