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Compound anti-aging quercetin nanoemulsion health care product

A quercetin and nanoemulsion technology, which is applied in the field of medicine, can solve the problems that the effect of quercetin cannot be fully utilized, and the quercetin cannot be fully utilized, so as to maintain the blood concentration and pharmacological effect, and reduce the first pass. effect, system transparency effect

Inactive Publication Date: 2012-08-15
NORTHWEST A & F UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] Quercetin has good anti-oxidation and anti-aging effects, but due to its own fat-soluble defects, the effect of quercetin cannot be fully utilized, so that quercetin cannot be fully utilized

Method used

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  • Compound anti-aging quercetin nanoemulsion health care product
  • Compound anti-aging quercetin nanoemulsion health care product

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0068]Accurately weigh 28g of EL40, 9g of ethyl acetate, 5.8g of quercetin, 4g of PEG200 and stir evenly with a magnetic stirrer at room temperature (25°C), then slowly drop into it the distilled water in which celery extract and mushroom extract have been dissolved . As the amount of distilled water increases, the viscosity of the system increases. When the amount of distilled water changes the system from water-in-oil to oil-in-water nanoemulsion, the viscosity of the system becomes thinner from the most viscous state, and what is produced at this time is Colorless and transparent compound quercetin nanoemulsion, 5.2 g of aqueous extract of celery, 4.7 g of aqueous extract of mushroom, and 43.3 g of distilled water were added. This ratio is the optimal ratio of quercetin antihypertensive nanoemulsion.

[0069] Following embodiment step is with embodiment 1:

Embodiment 2

[0071] Quercetin 6g, Tween 80 24g, isopropyl myristate 12g, ethanol 12g, celery water extract 4g, mushroom water extract 4g, distilled water 46g.

Embodiment 3

[0073] Quercetin 4g, RH40 28g, oleic acid 10g, PEG400 3g, celery water extract 5g, mushroom water extract 7g, distilled water 43g.

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Abstract

The invention discloses a compound anti-aging quercetin nanoemulsion health care product which comprises the following raw materials in mass percent: 1-15% of quercetin, 15-40% of surfactant, 1-15% of cosurfactant, 5-25% of oil, 1-15% of celery aqueous extract, 1-15% of mushroom aqueous extract, and the balance of distilled water; and the sum of mass percents of the above raw materials is 100%. The nanoemulsion is small in emulsion droplet, uniform in distribution, low in viscosity and good in liquidity. The compound anti-aging health care product takes fat soluble natural product quercetin with an efficient anti-aging effect as a main component, takes the celery aqueous extract and the mushroom aqueous extract as auxiliary components, has effects of keeping skin moisture, adjusting slumber, delaying senescence and adjusting immunologic function and has certain health care effect on diseases such as hypertension, hyperlipemia, hyperglycemia, heart disease and the like.

Description

technical field [0001] The invention belongs to the field of medicine, and relates to a new dosage form of an anti-aging health care product quercetin, in particular to a compound quercetin nanoemulsion anti-aging health care product. [0002] Background technique [0003] Quercetin (Quercetin), also known as quercetin, quercetin, soluble in glacial acetic acid, the alkaline aqueous solution is yellow, almost insoluble in water, and the ethanol solution tastes very bitter. [0004] Quercetin can significantly inhibit the effect of cancer-promoting agents, inhibit the growth of malignant cells in vitro, and inhibit the DNA, RNA and protein synthesis of Ehrlich ascites cancer cells. [0005] Quercetin can inhibit platelet aggregation and the release of 5-hydroxytryptamine (5-HT). Quercetin has obvious inhibitory effects on platelet aggregation induced by ADP, thrombin and platelet activating factor (PAF), among which the inhibitory effect on PAF is the strongest, and quercet...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/23A61K9/107A61K31/352A61P39/06A61P9/12
Inventor 欧阳五庆孙江宏郝明杰
Owner NORTHWEST A & F UNIV
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