Turpinia arguta seen leaf ethanol diacolation extract, preparation method thereof and application

A technology of percolation extraction and the round leaves of Shanxiang, which is applied in the field of ethanol percolation extracts and preparations of the round leaves of Shanxiang, can solve the problems of high price and achieve the goals of reducing infection, preventing and treating influenza and its complications, and inhibiting replication Effect

Inactive Publication Date: 2012-08-15
JIANGXI SHANXIANG PHARMA
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine "Oseltamivir Phosphate (Tamiflu, (3R, 4R, 5S)-4-Acetamide-5-Amino-3(1-Propoxyethyl)-1-Cyclohexene-1 Carboxylic Acid Ethyl Phosphate "Salt)" is a neuraminidase inhibitor, which has a specific inhibitory effect on the entry of influenza virus into cells, but it is not only expensive, but also some patients experience vomiting, nausea, insomnia, headache, abdominal pain, diarrhea, dizziness, fatigue, Side effects such as nasal congestion, sore throat, and coughing

Method used

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  • Turpinia arguta seen leaf ethanol diacolation extract, preparation method thereof and application
  • Turpinia arguta seen leaf ethanol diacolation extract, preparation method thereof and application
  • Turpinia arguta seen leaf ethanol diacolation extract, preparation method thereof and application

Examples

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Effect test

Embodiment 1

[0026] Preparation method: Take the coarse powder of the round leaves of Shanxiang, use 50% ethanol as the extractant, soak it for 24 hours, then carry out percolation at a speed of 7ml / kg / min, collect 11 times the percolation liquid of the medicinal material, recover the ethanol, and depressurize Concentrate to a thick paste or dry to obtain the ethanol percolation extract of Shanxiang round leaves.

Embodiment 2

[0028] Preparation method: take the round leaf powder of Shanxiang, use 60% ethanol as the extractant, soak for 48 hours, percolate at a speed of 2ml / kg / min, collect 9 times the amount of percolation liquid of medicinal materials, recover ethanol, and depressurize Concentrate to a thick paste or dry to obtain the ethanol percolation extract of Shanxiang round leaves.

Embodiment 3

[0030] Preparation method: take the coarse powder of the round leaves of Shanxiang, use 65% ethanol as the extractant, soak for 48 hours, and percolate at a speed of 5ml / kg / min, collect 8 times the percolation liquid of the medicinal material, recover the ethanol, and depressurize Concentrate to a thick paste or dry to obtain the ethanol percolation extract of Shanxiang round leaves.

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Abstract

The invention relates to application of turpinia arguta seen leaf ethanol diacolation extract in terms of preparation of medicines for suppressing neuraminidase. The extract is obtained by extracting turpinia arguta seen in a diacolation manner. The ethanol diacolation extracting method includes steps of taking turpinia arguta seen leaf coarse powder; using 25-90% of ethanol as extractant; performing diacolation at the speed ranging from 1ml / kg / minute to 18ml / kg / minute after steeping for 12 hours to 72 hours; collecting diacolation liquid with the volume 4-9 times of that of medicines; recycling the ethanol; and decompressing and concentrating the diacolation liquid to obtain thick paste or drying the diacolation liquid to obtain the turpinia arguta seen leaf ethanol diacolation extract.

Description

technical field [0001] The present invention relates to an ethanol percolation extract of Cymbidium saponifolium and its preparation method and application. Background technique [0002] At present, influenza virus is becoming more and more serious, and influenza virus is closely related to respiratory diseases and systemic diseases caused by it. my country is one of the countries with high incidence of influenza. Not only has a large population, but also living habits are conducive to the transmission of influenza virus. The average number of episodes ranged from 0.3 to 0.7, and 2 to 4 in key groups. Influenza poses a serious threat to human beings, especially the emerging strains of influenza virus, which not only cause secondary infections of other microorganisms, but also directly lead to organ damage and allergic reactions leading to death. But there is no effective method and treatment means for treating influenza virus and its disease (influenza) at present, such as t...

Claims

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Application Information

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IPC IPC(8): A61K36/185A61P31/16A61K127/00
Inventor 唐春山谢宁杨小玲张华敏王燕平刘地发李志勇文萍程帆蒋春红
Owner JIANGXI SHANXIANG PHARMA
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