Antihypertensive composition containing a ginsenoside-enriched fraction
A technology of ginsenoside and composition, applied in the field of blood pressure-lowering compositions, can solve the problems of small quantity, lack of standardization information of ginsenosides, etc., and achieve the effects of increasing the generation of nitric oxide and preventing hypertension
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Embodiment 1
[0028] Embodiment 1: the preparation of ginsenoside concentrated fraction of the present invention
[0029] 1-1: Preparation of ginseng ethanol extract
[0030] Add 70% ethanol to 1 kg of dried tail ginseng, the amount of which is 15 times the weight of the sample, and extract at 70° C. for 24 hours to obtain a ginseng ethanol extract.
[0031] Adopt high performance liquid chromatography (HPLC) to measure the content of ginsenoside Rg1 and Rb1 in the ginseng ethanol extract that obtains, and its result is shown in table 1 and figure 1 .
[0032] 1-2: Preparation of ginsenoside concentrated fraction
[0033] The ethanol extract of ginseng obtained in the above example 1-1 was heated and concentrated to make the Brix degree 80brix. Add distilled water 5 times the weight of the concentrate, fully dilute, and then pass formaldehyde-based HP-20 adsorption resin to absorb saponin components, and continue to pass distilled water about 5 times the volume of the above resin to remo...
Embodiment 2
[0039] Example 2: Preparation of composition tablet for lowering blood pressure containing ginsenoside concentrated fraction of the present invention
[0040] 25 mg of the ginsenoside concentrated fraction obtained in Example 1 was mixed with 270 mg of crystalline cellulose and 200 mg of dextran. Then, 2.5 mg of magnesium and 2.5 mg of hydroxypropylmethylcellulose were added to the above mixture to prepare it.
Embodiment 3
[0041] Example 3: Preparation of the composition capsule for lowering blood pressure containing ginsenoside concentrated fraction of the present invention
[0042] 500 mg of the ginsenoside concentrated fraction obtained in Example 1 was filled into soft gelatin capsule shells, thereby preparing capsules.
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