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Antibacterial fibre containing nano-metal, fabric and wound dressing, and preparation method thereof

A nano-metal and wound dressing technology, applied in botanical equipment and methods, fabrics, fiber processing and other directions, can solve the problems of falling off, difficult to achieve high content, and unable to ensure that the wound dressing can continuously release a sufficient amount of silver particles. Infection prevention, long-term and effective antibacterial effect

Active Publication Date: 2012-05-16
GUANGDONG BAIHE MEDICAL TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, the use of silver compounds sometimes cannot meet this requirement
In addition, in the prior art, although there are dressings using metallic silver particles, or even nano-silver particles as an antibacterial agent, they are all applied to the surface of fibers or fabrics by padding, dipping, and vapor deposition methods. Or nano-silver particles are only adsorbed on the surface of fibers or fabrics, and it is difficult to achieve a high content
In addition, because the silver particles of these dressings are only on the fiber surface, once the dressing absorbs the wound secretion, these silver particles may fall off due to factors such as surface moisture absorption, gelation or softening.
Therefore, it is impossible to ensure that the wound dressing continuously releases a sufficient amount of silver particles to meet the needs of patients with chronic wounds

Method used

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  • Antibacterial fibre containing nano-metal, fabric and wound dressing, and preparation method thereof
  • Antibacterial fibre containing nano-metal, fabric and wound dressing, and preparation method thereof
  • Antibacterial fibre containing nano-metal, fabric and wound dressing, and preparation method thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0052] The method for preparing antibacterial fiber containing nano silver and wound dressing thereof:

[0053] 1. Add the specified amount of water into the mixing container

[0054] 2. Calculate the amount of sodium alginate according to the moisture content of the alginate powder and the required solid content. For example, the water content of sodium alginate is 10% by weight, the solid content required for spinning dope is 5% by weight, and 20 kg of sodium alginate powder requires 342 liters of water.

[0055] 3. Calculate the required amount of nano-silver. For a product containing 5% by weight of silver (moisture content in nano-silver is ignored) and 18 kg of seaweed sodium, about 0.9 kg of nano-silver is needed.

[0056] 4. the above-mentioned nano-silver powder (particle diameter 5nm, D 95 =3.7-6.9) First, the nano-silver is dispersed in the aqueous solution with an ultrasonic instrument (25-50 Hz), and the aqueous solution contains 20% by weight of the nano-silve...

Embodiment 2

[0065] In order to observe the antibacterial performance of the dressing, a certain amount of Staphylococcus aureus was evenly coated in a petri dish, and then the dressing obtained in Example 1 was cut into 2×2 cm and placed in it, and cultured continuously for 7 days at a constant temperature of 37°C , observe the bacterial growth on each plate every day. figure 1 shows the zone of inhibition of the dressing containing 5% by weight of nanosilver in a Staphylococcus aureus petri dish after 1 day, figure 2 Zones of inhibition of dressings containing 5 wt% nanosilver in S. aureus petri dishes after 7 days are shown. It can be seen that the dressing containing 5% by weight nano-silver still has good antibacterial performance after 7 days.

Embodiment 3

[0067] The method for preparing the antibacterial fiber and wound dressing thereof containing nanometer copper 1.5% by weight:

[0068] 1. Fill the mixing container with a known amount of water

[0069] 2. Calculate the amount of sodium alginate according to the moisture content of the alginate powder and the required solid content. For example, the water content of sodium alginate is 10% by weight, the solid content required for spinning dope is 5% by weight, and 20 kg of sodium alginate powder requires 342 liters of water. The dry weight of sodium alginate powder is 18 kg.

[0070] 3. Prepare nano-copper aqueous solution, the calibration particle size is 400 nm, and the actual distribution is 300-550 nm.

[0071] 4. For the product containing 1.5% by weight of copper and 18 kg of sodium seaweed dry weight, about 1.35Kg of 20% by weight nano-copper aqueous solution (270 grams of nano-copper weight) is needed.

[0072] 5. Put 4 kg of sodium alginate powder into a stirring c...

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Abstract

The invention relates to antibacterial fibre containing nano-metal, fabric and wound dressing, and a preparation method thereof; nano-metal particles are uniformly distributed in the fibre structure and on the fibre surface; a colloid protective agent for preventing nano-metal from condensing does not exist in the fibre; the content of the nano-metal particles is 1.1-20% by weight; the fibre wound dressing as the wound treating dressing has the capability of continuously releasing enough nano-metal particles; and the fibre wound dressing is particularly applied to chronic wound therapy and can provide long-term and effective antibacterial function and effectively prevent various bacteria and microorganisms from infecting wounds.

Description

technical field [0001] The invention relates to an antibacterial fiber and a preparation method thereof, a fabric and a wound dressing made from the antibacterial fiber, and a preparation method of the wound dressing. Background technique [0002] Silver and copper are well known, and silver in particular has long been recognized for its potent antimicrobial properties, particularly against some of the bacteria commonly found in the care of chronic wounds. Moreover, the bactericidal effect of silver on certain antibiotic-resistant bacteria has been shown. At present, the most common antibacterial silver-containing dressings are divided into ionic type and nano-metal type. The use of silver ion technology is to provide silver ions to the wound dressing used through a silver compound, and the use of nano-metal technology is to make nano Metals such as nanoparticles of silver are applied to the wound dressing. [0003] When preparing antibacterial fibrous wound dressings, the...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): D01F1/10D01F9/04D01F9/00D01F2/08D01D1/02D01D5/40A61L15/44A61L15/28A61L15/18
CPCD01F2/10A61L15/18D01F1/103A01N25/10D01F9/04A61L15/425A61L2300/102D01D5/06D10B2401/13D03D15/00A61L2300/404D10B2509/022A61L2400/12A61L15/46D10B2101/20A61L15/24C08L5/02C08L5/04
Inventor 王晓东王锐岑荣章
Owner GUANGDONG BAIHE MEDICAL TECH CO LTD
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