Compound oil-in-water type largehead atractylodes rhizome oil nanoemulsion composition and preparation method thereof

Abstract

The invention discloses a compound oil-in-water type largehead atractylodes rhizome oil nanoemulsion composition. The nanoemulsion composition has a diameter size which ranges from 1 nm to 100 nm and consists of the following substances in percentage by mass: 0.1-7.5 percent of largehead atractylodes rhizome oil, 0.1-5.0 percent of atractylis oil, 0.1-5.0 percent of cinnamaldehyde, 0.1-3.0 percent of patchouli oil, 0.05-3.0 percent of dried tangerine peel oil, 0.05-2.0 percent of costus root oil, 0-32.0 percent of polyoxyethylene ether castor oil, 0-32.0 percent of polyoxyethylene (40) hydrogenated castor oil and the balance of distilled water, wherein the sum of the mass percentages of the components is 100 percent. The nanoemulsion composition has the effects of resisting gastrointestinal ulcer, resisting inflammation, adjusting gastrointestinal motility, and secretion of digestive juice, invigorating spleen, harmonizing stomach, eliminating dampness, tonifying spleen, stopping vomiting, sterilizing and the like. The nanoemulsion composition can be used for treatment, daily stomach health care and the like of gastric ulcer, duodenal ulcer and various kinds of acute and chronic gastritis.

Description

Technical field [0001] The invention is a pharmaceutical field, involving a treatment method for gastric ulcers, duodenal ulcers, and various acute and chronic gastritis and daily stomach healthy pantylast oil -type albumon oil nanomal milk and their preparation methods. Background technique [0002] Ulcer disease is a common chronic disease. Among them, digestive ulcers are the most common, mainly with gastric ulcer and duodenal ulcer, etc., which are also called "gastric pain" and "liver and stomach pain" in traditional Chinese medicine.The rhythmic upper abdominal pain of repeated attacks is a clinical characteristics. It is often accompanied by feelings such as radon, acid return, burning, etc. In severe cases, there are nausea, vomiting, and vomiting blood.The cause of this disease is complicated, including genetic factors, living factors, chemical factors, drug factors and mental factors. Australian scientist Marshall proves that the Nobel Prize in physiology and medicine i...

AI Technical Summary

Problems solved by technology

At present, the utilization of Atractylodes Rhizome Oil is mainly limited to the original drug. Although it has a certain curative effect, the active ingredients of the drug are not fully utilized, the drug absorption rate is low, and the bioavailability after oral administration is not high, which directly affects the popularization and utilization of Atractylodes Rhizome.

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