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A composition with anti-alcoholic and liver-protecting effects, its preparation method and application

A composition and a technology for detoxifying and protecting the liver are applied in the field of compositions with the properties of detoxifying and protecting the liver, and can solve the problems of inability to remove ethanol and its metabolite acetaldehyde, no obvious protective effect, damage to the central nervous system of the human body, and the like. The effect of adjuvant treatment of alcohol allergy, improving people's ability to react after drinking, and protecting the central nervous system

Inactive Publication Date: 2011-12-21
SUN YAT SEN UNIV
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

This kind of anti-alcoholic medicine is characterized by taking it before drinking to reduce the amount of alcohol entering the blood, and taking it after drinking can not remove ethanol and its metabolite acetaldehyde
The second category is hepatoprotective drugs, which mainly have a protective effect on the liver system, but have no obvious protective effect on other systems, such as the cardiovascular system.
The third type is the stimulant type. The drug enters the body to produce a corticosteroid stress effect, neutralizes the inhibitory effect of alcohol on the central nervous system, and achieves the purpose of sobering up. damage to the central nervous system
In addition, none of the three anti-alcohol drugs were effective in treating alcohol allergies

Method used

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  • A composition with anti-alcoholic and liver-protecting effects, its preparation method and application
  • A composition with anti-alcoholic and liver-protecting effects, its preparation method and application
  • A composition with anti-alcoholic and liver-protecting effects, its preparation method and application

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0017] Preparation of hangover vinegar

[0018] (1) Take 120kg of kudzu root, 200kg of Hovenia dulcis, 15kg of hawthorn, 15kg of ebony plum, 50kg of chrysanthemum, and 100kg of reed rhizome, add 8 times the volume of water, heat and extract for 2 hours, filter, add 3 times the volume of water to extract the filter residue for 5 hours, and combine the two filtrates, Adjust the amount of crude drug to be 120g / L;

[0019] (2) Add clarifying agent, let stand for 12h, filter;

[0020] (3) add alanine 3kg, glutamine 4kg to filtrate, stir;

[0021] (4) Add vinegar and sugar to the mixture in step (3) to obtain hangover vinegar.

Embodiment 2

[0023] Preparation of Hangover Capsules

[0024] (1) Get 100kg of kudzu root, 100kg of Hovenia dulcis, 50kg of hawthorn, 50kg of black plum, 50kg of chrysanthemum, and 50kg of reed rhizome, add 10 times the volume of 90% ethanol to reflux and extract twice, filter, merge the filtrate twice, and concentrate to obtain extractum;

[0025] (2) add 200-250kg dextrin to the extract, dry and pulverize to obtain extract powder;

[0026] (3) Add 2.5-3kg of alanine and 3.5-4kg of glutamine to the extract powder, mix well, and then pack into capsules to obtain.

Embodiment 3

[0028] Preparation of Hangover Tablets

[0029] (1) Take 100kg of kudzu root, 100kg of Hovenia dulcis, 50kg of hawthorn, 50kg of black plum, 50kg of chrysanthemum, and 50kg of reed root, add 8 times the volume of hydrothermal extraction for 1 hour, filter, add 4 times the volume of hydrothermal extraction for 0.5 hours. Combine the two filtrates, concentrate to a relative density of 1.02, add 95% ethanol until the percentage of ethanol is 60%, and then let stand for more than 10h;

[0030] (2) filter and concentrate the filtrate to a relative density of 1.18;

[0031] (3) Add dextrin, 2.5kg of alanine, and 4kg of glutamine to make a soft material, sieve, and press into tablets.

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PUM

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Abstract

The invention discloses a composition with anti-alcoholic and liver-protecting effects, a preparation method and application thereof. It is composed of kudzu root, Hovenia dulcis, hawthorn, chrysanthemum, black plum, reed root, alanine, and glutamine in proportion, and can be processed into various products with the effect of relieving alcohol and protecting the liver. The composition has the functions of improving human body's tolerance to alcohol, preventing acute alcohol poisoning, assisting the treatment of alcoholic liver damage and alcohol allergy, and the like. In addition, the present invention also relates to a method for making the composition into various foods and medicines.

Description

Technical field [0001] The present invention involves a composition and preparation method and application with alcohol and liver protection. Background technique [0002] China is a large country of wine production. It consumes more than 2 million tons of alcoholic beverages each year. The alcohol or alcohol dependence rely on the crowd to reach about 200 million.Acute alcohol poisoning is commonly known as drunk, which refers to the loss process of the central nervous system, digestive system, respiratory system, cardiovascular and cerebrovascular system caused by drinking excessive alcohol or alcoholic beverages.Death and so on.The incidence of fatty liver, liver cirrhosis, and liver cancer caused by chronic alcohol poisoning has increased year by year, and it is one of the main causes of liver injury of the people of my country.Therefore, according to the physical characteristics of the Chinese people, combined with the principles of alcoholism and metabolism, the alcohol -re...

Claims

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Application Information

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IPC IPC(8): A61K36/899C12J1/00A23L1/29A61P39/00A61P1/16A61K31/198A61K31/197A23L33/00
Inventor 苏薇薇林婉玲罗铝铿王永刚李沛波彭维吴忠
Owner SUN YAT SEN UNIV
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