Chinese medicinal composition for treating trichomonas vaginitis and preparation method thereof
A trichomonal vaginitis and composition technology, applied in the direction of drug combination, pharmaceutical formula, hydroxyl compound active ingredients, etc., can solve the problem of inability to achieve anti-inflammatory and antipruritic effects, unsatisfactory therapeutic effect, unsatisfactory curative effect, etc. problems, to achieve good social value and economic benefits, convenient administration, and rapid antipruritic effects
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preparation example Construction
[0058] The preparation method of the honey refining pill for oral administration of the present invention is: take Radix Polygoni Multiflori 1000g, Angelica 1000g, Atractylodes macrocephala 1000g, Chinese yam 1000g, Astragalus 1000g, Jujube 1000g, Cuscuta 1000g, Millis Spatholobus 1000g, Mulberry 1000g, Alisma 1000g, Eclipta Grass 1000g, raspberry 1000g, rehmannia glutinosa 1000g, scutellaria baicalensis 1000g, paeonol 1000g; the raw material drug for oral administration is first pulverized into coarse powder, then further pulverized, and passed through a 100-120 mesh sieve to obtain a fine powder that can pass through the sieve When the amount reaches 30%, collect the fine powder that passes through the sieve to obtain fine powder a; then put the coarse powder that cannot pass through the 120 mesh sieve into a multi-functional extraction tank for extraction twice, add 10 times the amount of water for the first time and decoct for 1 hour, the second time Add 8 times the amount ...
experiment example 2
[0073] Experimental example 2: long-term toxicity test data
[0074] 1. Experimental method
[0075] The guinea pigs were randomly divided into 4 groups, 15 in each group. Apply the depilatory agent evenly on both sides of the back spine of the guinea pig, so that the range of depilation is about 40 square centimeters. Clean the depilatory agent, observe each group of guinea pigs after 24 hours to be coated with respectively 0.2,0.4 and 0.8ml of the present invention's orally administered traditional Chinese medicine preparation Honey Refined Pills, contain crude drug 92,184 and 368mg respectively, another group is coated with vehicle 0.8ml twice a day, For 30 consecutive days, the general condition of the guinea pigs was observed. After the experiment, the animals were sacrificed for hematology, blood biochemical and pathological examinations.
[0076] 2. Results
[0077] No edema, hyperemia, erythema, bleeding spots and ulcers were found in the depilated trunk area of g...
experiment example 3
[0078] Experimental example 3: Cumulative toxicity test:
[0079] Traditional Chinese medicine preparation of the present invention is taken orally honey refined pills to mice by 7.69, 19.18 and 43.21g crude drug / kg continuous medication 15 weeks (1.0ml / 100g body weight, every day 2 times) and after drug withdrawal 3 weeks, the result shows: Chinese medicine of the present invention The preparation has no obvious effect on the hair, behavior, defecation, body weight, organ weight, blood picture, liver and kidney function, blood sugar, blood lipid and other indicators of rats. After 1 week and 3 weeks after stopping the drug, there was no significant change in the organs of the rats. It shows that the oral capsule of the traditional Chinese medicine preparation of the present invention has little toxicity to rats after long-term administration, and there is no abnormal reaction after drug withdrawal, so the application is safe.
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