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Compound polyhexamethylene guanidine antibacterial hand sanitizer and preparation method

A technology of polyhexamethylene guanidine and antibacterial hand sanitizer, applied in the field of hand sanitizer, can solve problems such as incompatibility, and achieve the effects of reducing irritation, increasing decontamination ability, and increasing stability

Inactive Publication Date: 2011-04-20
SHANGHAI LIKANG DISINFECTION HIGH TECH
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Polyhexamethylene guanidine is cationic and has incompatibility with anionic surfactants

Method used

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Examples

Experimental program
Comparison scheme
Effect test

preparation example Construction

[0040] The preparation process of the hand sanitizer of the present invention is very simple, the time consumption is short, the operation is convenient, and at the same time, the requirements for equipment are low, only a stirring reaction kettle and an electric heater are sufficient. The specific preparation process is: add a sufficient amount of water to the reaction kettle, heat up to 60-80°C, add cellulose under stirring, and after it is completely swollen (about 60 minutes), add nonionic surfactant, Fat-filling agent, non-ionic surfactant, humectant, mix well, then add cationic surfactant, PHMB, stir for 5 minutes, when the feed liquid in the reaction kettle drops to room temperature, adjust the feed liquid to the pH value with an appropriate amount of citric acid To neutral, it can be filled after standing still for defoaming.

[0041] The invention enriches the hand sanitizer market and provides a new choice for users.

example 1

[0042] Example 1: PHMB 0.2, Brogeramine 0.2, Hydroxyethylcellulose 1.0, Fatty Acid Diethanolamine 5.0, Polyoxyethylene (7) Glyceryl Cocoate 4.0, Cocamidopropyl Betaine 10.0, Glycerin 2.0, Citric Acid 0.5-1.5, the rest is water.

example 2

[0043] Example 2: PHMB 0.3, Geeramine 0.2, Hydroxypropyl Cellulose 1.0, Fatty Alcohol Polyoxyethylene Ether 5.0, Polyoxyethylene (7) Glycerin Cocoate 4.0, Cocamidopropyl Betaine 8.0, Propylene Glycol 2.0 , citric acid 0.5-1.5, the rest is water.

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PUM

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Abstract

The invention relates to an antibacterial hand sanitizer containing polyhexamethylene guanidine, in particular to a compound polyhexamethylene guanidine antibacterial hand sanitizer. The compound polyhexamethylene guanidine antibacterial hand sanitizer is characterized in that: the antibacterial hand sanitizer comprises the following ingredients by weight percentage: 0.1-1.0 of PHMB (polyhexamethylene biguanidine), 0.1-0.5 of cationic surface active agent, 0.5-1.0 of cellulose, 4.0-7.0 of non-ionic surface active agent, 1.0-3.0 of lipotropic agent, 4.0-8.0 of amphoteric surfactant, 1.0-2.0 of glycerol, 0.5-1.5 of citric acid and the balance water. The preparation method of the antibacterial hand sanitizer comprises the following steps: enough water is added in an agitated reactor, and the temperature is heated to 60-80 DEG C, cellulose is added in water under stirring, after the cellulose is completely swelled, the non-ionic surface active agent, the lipotropic agent, the amphoteric surfactant and the glycerol are sequentially added, after the mixture is mixed evenly, bromogeramine and the PHMB are added and are stirred for five minutes, when the temperature of a feed liquid in the agitated reactor is reduced to room temperature, a proper amount of citric acid is added to adjust the pH value of the feed liquid to be neutral, and filling can be carried out on the mixture subjected to standing and defoaming. In the antibacterial hand sanitizer provided by the invention, a cationic surface active agent is compounded as a sterilization ingredient and has synergy function, and the antibacterial hand sanitizer is used for washing easily without irritation.

Description

technical field [0001] The invention relates to a hand sanitizer, in particular to an antibacterial hand sanitizer containing polyhexamethylene guanidine. Background technique [0002] Antibacterial hand sanitizers currently on the market use DP300 (triclosan) and PX (4-chloro-3,5-xylenol) as fungicides. The variety is relatively single, and long-term use is prone to drug resistance. Moreover, DP300 and PX have poor water solubility and are difficult to prepare. Hand sanitizers using these two disinfectants must add pigments, otherwise the hand sanitizer will change color after a period of storage. [0003] Polyhexamethyleneguanidine (PHMB), a polymer of hydrochloride (hexamethylenebiguanide), is a broad-spectrum and rapid novel fungicide used as a bactericidal, antibacterial and antiseptic in professional disinfection and household products Element. PHMB can quickly act on bacteria, viruses and pathogens, and its mode of action includes the following ways: quickly attract...

Claims

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Application Information

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IPC IPC(8): A61K8/84A61Q19/10
Inventor 张忠敏李靖邹贤信
Owner SHANGHAI LIKANG DISINFECTION HIGH TECH
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