Medicament for treating metrorrhagia and metrostaxis, hematemesis, hematochezia and traumatic hemorrhage and preparation method thereof

Abstract

The invention relates to a medicament for treating metrorrhagia and metrostaxis, hematemesis, hematochezia and traumatic hemorrhage and a preparation method thereof. The preparation method comprises the following steps of: 1, mixing rhubarb, golden thread and dahurian angelica root, adding an ethanol, merging ethanol extract, and concentrating the ethanol extract; 2, adding sanchi into the ethanol, merging ethanol extract and concentrating the ethanol extract; 3, taking common bletilla pseudobulb decocting liquid and concentrating the liquid into a thick paste with a relative density between 1.15 and 1.30 at the temperature of 60 DEG C; 4, decocting dregs in the three steps, India madder root and liquoric root twice, merging decoction, concentrating the decoction, mixing the concentrated decoction with the thick paste obtained in step 3, reducing pressure and drying the mixture to obtain a dry paste and crushing the dry paste; 5, evenly mixing products obtained by step 1 and step 2, carrying out high-speed centrifugal spraying drying, and simultaneously spraying aqueous solution of hydroxypropyl-beta-cyclodextrin to prepare dispersed fine powder; and 6, mixing and crushing medicaments such as cuttlebone, calcined dragon bone and the like, evenly mixing the mixture with two fine powder obtained by the step 4 and step 5, adding medicaments such as microcrystalline cellulose and the like, and evenly mixing, drying and palletizing the mixture. The medicament simplifies production process, saves production cost and has obvious curative effect.

Description

technical field [0001] The invention relates to a medicine and a preparation method, in particular to a medicine and a preparation method for treating uterine bleeding, hematemesis, blood in the stool and traumatic bleeding. Background technique [0002] Metrorrhagia, hematemesis, hematochezia, and traumatic bleeding are common blood diseases in traditional Chinese medicine. The syndrome type of traditional Chinese medicine is that the heat and toxin are flourishing, blocking the veins, and the blood heat is caused by women's metrorrhagia; women's postpartum hemorrhage in the birth canal; women's family planning Vaginal bleeding after surgery; gastric and duodenal ulcer bleeding; ulcerative colitis bleeding, mole bleeding; orthopedic limb fractures, trauma, contusion, etc. [0003] Patent [0004] A drug for treating metrorrhagia, hematemesis and hematochezia” (Patent No.: ZL200510096362.6) discloses a drug for treating metrorrhagia, hematemesis and hematochezia, its capsul...

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Problems solved by technology

[0004] A drug for treating metrorrhagia, hematemesis and hematochezia” (Patent No.: ZL200510096362.6) discloses a drug for treating metrorrhagia, hematemesis and hematochezia, its capsule prescription and the extraction of active ingredients and capsule preparation method. Capsules have a large dosage, three times a day, 2-4 capsules at a time; storage in cool conditions is required, and they are easy to absorb moisture and agglomerate when sold in the south of the Yangtze River, resulting in slow disintegration and poor bioavailability, which affects the efficacy of the drug; due to the expiration date Short, unstable quality, which seriously restricts its clinical application and large-scale production, so that the real good clinical application value of the drug cannot be fully realized

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