Effervescent tablets for women as well as preparation method and application thereof

A technology of effervescent tablets and raw materials, which is applied in the direction of pharmaceutical formulas, medical preparations containing active ingredients, and medical preparations containing active ingredients. It can solve the problems of large adverse reactions and easy recurrence, and achieve long storage period, Overcoming poor stability and easy to use

Active Publication Date: 2009-07-22
XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Western medicine treatment has the characteristics of severe adverse reactions, especially liver and kidney toxicity; after termination of treatment, it is easy to relapse

Method used

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  • Effervescent tablets for women as well as preparation method and application thereof

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0029] Embodiment 1: (based on making 1000 pieces)

[0030] a. First weigh 280g of Coptidis Rhizoma Coptidis and crush it into coarse powder, add 5 times the amount of 50% ethanol to reflux and extract once for 3 hours, filter, recover ethanol from the filtrate under reduced pressure and concentrate it to an extract with a relative density of 1.22-1.25 , concentrated at 60°C, concentrated and dried under reduced pressure to obtain extract powder, pulverized, passed through a 60-mesh sieve, and set aside;

[0031] b. Weigh 220g of pomegranate peel, 250g of coral, and 50g of Mituseng, respectively, and grind them into coarse powder, add 5 times the amount of water to decoct once for 3 hours, filter, and concentrate the filtrate to a relative density of 1.22-1.25 Extract, concentrated at 60°C, concentrated and dried under reduced pressure to obtain extract powder, pulverized, passed through a 60-140 mesh sieve, and set aside;

[0032] c. After heating and melting the auxiliary m...

Embodiment 2

[0037] Embodiment 2 (based on making 1000 pieces)

[0038] a. First weigh 300 g of Coptidis rhizome and crush it into a coarse powder, add 8 times the amount of 60% ethanol to reflux and extract twice, each time for 2 hours, filter, and the filtrate is decompressed to recover ethanol and concentrate to a leaching solution with a relative density of 1.22-1.25. paste, concentrated at 60°C, concentrated and dried under reduced pressure to obtain extract powder, pulverized, passed through a 80-mesh sieve, and set aside;

[0039] b. Weigh 350g of pomegranate peel, 300g of coral, and 100g of Mituseng, respectively, and grind them into coarse powder, add 8 times the amount of water to decoct twice, each time for 2 hours, combine the decoction, filter, and concentrate the filtrate to the relative Density 1.22-1.25 extract, concentrated at 60°C, concentrated and dried under reduced pressure to obtain extract powder, crushed, passed through 80-mesh sieve, and set aside;

[0040] c. Aft...

Embodiment 3

[0045] Embodiment 3 (based on making 1000 pieces)

[0046] a. First weigh 450 g of Coptidis rhizome and crush it into coarse powder, add 20 times the amount of 70% ethanol to reflux and extract 3 times, each time for 1.5 hours, filter, and the filtrate is decompressed to recover ethanol and concentrate to a leaching solution with a relative density of 1.22-1.25. paste, concentrated at 60°C, concentrated and dried under reduced pressure to obtain extract powder, crushed, passed through a 100-mesh sieve, and set aside;

[0047] b. Weigh 450g of pomegranate peel, 450g of coral, and 250g of Mituseng, respectively, as raw materials, grind them into coarse powder, add 15 times the amount of water to decoct 3 times, each time for 1.5 hours, combine the decoction, filter, and concentrate the filtrate to The extract with a relative density of 1.22-1.25, concentrated at 60°C, concentrated and dried under reduced pressure to obtain extract powder, crushed, passed through a 100-mesh sieve...

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PUM

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Abstract

The invention relates to an external gynaecological inflammation clean effervescent tablet with antibiotic activity, a method for preparing the same and application thereof. The effervescent tablet is prepared from rhizoma coptidis, pomegranate bark, coral, litharge, sodium bicarbonate, polyethyleneglycol 6000, citric acid, lactose, polyvinylpyrrolidone, magnesium stearate and superfine silica gel powder, and has the advantages of clearing heat and drying damp, killing insects and relieving itching, giving a play to strong inhibition on woman vagina pathogen, high safety and good stability, and having no obvious toxic side effects and drug resistance as well as convenience to use, carry and store by a patient. The effervescent tablet is applied to treating various gynaecological diseases of colpitis, vulvitis, and the like caused by infusorium, fungi and bacteria, and can be used as a preventive medicine for long term usage simultaneously.

Description

technical field [0001] The invention relates to an external antibacterial effervescent tablet for women made of pure traditional Chinese medicine. Background technique [0002] Gynecological diseases refer to diseases caused by infections of the female reproductive system. Due to the particularity of female reproductive organs, gynecological diseases have become common and frequently-occurring diseases in adult women, with various clinical manifestations, complicated etiology and often accompanied by a variety of serious complications, which have brought great impact on women's life and work. influences. In addition, with today's environmental pollution, competitive pressure, accelerated pace of work, and changes in lifestyle, gynecological diseases will continue to increase, and will show a trend of younger and younger age. According to the survey of Chinese women by the World Health Organization, 41% of female patients in China have different degrees of vaginal inflammat...

Claims

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Application Information

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IPC IPC(8): A61K36/718A61K9/46A61K47/38A61P15/02A61P31/02A61P31/10A61P33/02A61K33/24A61K35/56A61K35/614
Inventor 阿吉艾克拜尔·艾萨罗玉琴阿不都吾甫尔·热依木古丽李杨
Owner XINJIANG TECHN INST OF PHYSICS & CHEM CHINESE ACAD OF SCI
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