Looking for breakthrough ideas for innovation challenges? Try Patsnap Eureka!

Preparation and application of ceftibuten dry suspension agent

A technology of dry suspension and ceftibuten, which is applied in the new field of medicine, can solve problems such as inconvenience, and achieve the effects of high quality, simple method and good stability

Inactive Publication Date: 2009-07-01
BEIJING HOPE HUGE PHARM SCI
View PDF0 Cites 6 Cited by
  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

However, most of the third-generation varieties need to be administered by injection, which is very inconvenient

Method used

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
View more

Image

Smart Image Click on the blue labels to locate them in the text.
Viewing Examples
Smart Image
  • Preparation and application of ceftibuten dry suspension agent

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0028] Example 1: Specification 1000 bags

[0029] prescription:

[0030] Ceftibuten 200g 400g

[0031] Cane sugar 1800g 1800g

[0032] Mannitol 250g 250g

[0033] Sodium Chloride 10g 10g

[0034] Carbomer 1.6g 1.6g

[0035] Aspartame 1g 2g

[0036] Strawberry Flavor 0.4g 0.4g

[0037] 50% ethanol appropriate amount appropriate amount

[0038] Method:

[0039] Pass cefbutene, sucrose, mannitol, and sodium chloride through an 80-mesh sieve respectively, weigh them according to the recipe, mix them evenly, add 50% ethanol to make soft material, granulate, dry at 60°C (moisture <1.0%), and then make the whole product. granules, and then add the adjuvant carbomer, strawberry essence, aspartame, mix evenly, and divide the intermediate after passing various quality inspections.

Embodiment 2

[0040] Example 2: Specification 10000 bags

[0041] prescription:

[0042] Ceftibuten 2000g 4000g

[0043] Cane sugar 18000g 18000g

[0044] Mannitol 2500g 2500g

[0045] Sodium Chloride 100g 100g

[0046] Carbomer 16g 16g

[0047] Aspartame 10g 20g

[0048] Strawberry Flavor 4g 4g

[0049] 50% ethanol appropriate amount

[0050] Method:

[0051] Pass cefbutene, sucrose, mannitol, and sodium chloride through an 80-mesh sieve respectively, weigh them according to the recipe, mix them evenly, add 50% ethanol to make soft material, granulate, dry at 60°C (moisture <1.0%), and then make the whole product. granules, then add the adjuvant carbomer, strawberry essence, aspartame, mix evenly, and divide the intermediate after passing various quality inspections.

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

PUM

No PUM Login to View More

Abstract

The invention belongs to the novel technology field of the medicines and relates to a preparation and use of a ceftibuten dry suspension. The ceftibuten dry suspension is characterized by comprising, but not being limited by following excipients available by pharmacy: sucrose, mannitol, etc. as the loading agent; sodium chloride, aspartame, strawberry essence, etc. as the flavoring agent; carbomer, sodium carboxymethyl cellulose, sodium carboxy nethyl, etc. as the suspending agent. The ceftibuten dry suspension is used for treating: upper respiratory tract infection such as pharyngitis, antiaditis, scarlet fever, paranasal sinusitis, and otitis medium; lower respiratory tract infection such as acute bronchitis, acute attack of chronic bronchitis and pneumonia; urinary tract infection; enteritis and gastroenteritis.

Description

technical field [0001] The invention belongs to the field of new pharmaceutical technology, and relates to a new dosage form of cefbutene, which is used for treating upper respiratory tract infections such as pharyngitis, tonsillitis, scarlet fever, paranasal sinusitis and otitis media; lower respiratory tract infections such as acute bronchitis, acute bronchitis and chronic bronchitis Attack, pneumonia; urinary tract infection; enteritis and gastroenteritis. Specifically, the preparation and application of a ceftibuten dry suspension. Background technique [0002] Cephalosporin antibiotics have the characteristics of broad antibacterial spectrum, strong antibacterial activity, high efficacy and low toxicity. Since the first-generation cephalosporin cefotaxime was successfully developed in China in the 1970s, cephalosporin antibiotics have developed rapidly in my country. In 2001, the national sales of cephalosporin antibiotics reached 16 billion yuan, and the annual rate o...

Claims

the structure of the environmentally friendly knitted fabric provided by the present invention; figure 2 Flow chart of the yarn wrapping machine for environmentally friendly knitted fabrics and storage devices; image 3 Is the parameter map of the yarn covering machine
Login to View More

Application Information

Patent Timeline
no application Login to View More
IPC IPC(8): A61K31/546A61K9/16A61K47/32A61P1/00A61P11/00A61P11/02A61P11/04A61P13/00A61P27/16
Inventor 王翰斌闫艳立吴广俣
Owner BEIJING HOPE HUGE PHARM SCI
Who we serve
  • R&D Engineer
  • R&D Manager
  • IP Professional
Why Patsnap Eureka
  • Industry Leading Data Capabilities
  • Powerful AI technology
  • Patent DNA Extraction
Social media
Patsnap Eureka Blog
Learn More
PatSnap group products

Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.

© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com