Alkaloid compounds, preparation method and application thereof

Abstract

The invention relates to an alkaloid compound extracted and prepared from a cat bean and a valid target, wherein, the cat bean is used as a raw material, the valid target is obtained through crushing, solvent extraction, separation and purification by resin or silica gel column chromatography and other methods, and the compound, 1, 2-dihydro-3-guanido-6-hydroxymethyl-1-methylpyrazine-2-ketone, namely cat-bean guanidine, is obtained by separation of the valid target. Pharmacodynamical experiments prove that: the compound has sedative-hypnotic function, and can be used as a pharmaceutical and chemical raw material and be prepared into sedative-hypnotic preparation.

Description

Technical field: [0001] The invention belongs to the fields of natural medicinal chemistry and medicine, and relates to an alkaloid compound extracted and prepared from cat bean, its effective part and its application in sedative and hypnotic effects. Background technique: [0002] Cat bean is the seed of Stizolobium cochinchinensis (Lour) Tang et Wang, a plant of the leguminous genus Stizolobium cochinchinensis (Lour) Tang et Wang. It is a characteristic medicinal and edible resource and a commercial crop in Guangxi. Cat bean is the most important raw material for extracting levodopa. Extracting levodopa from cat bean has become the main source of levodopa raw material in the world. The research on the key technology of high-purity and efficient extraction of levodopa completed by the applicant has been transformed, making Guangxi an international production base of levodopa. The research on other chemical components of cat bean is of great significance to the extension of...

AI Technical Summary

Problems solved by technology

At present, the drugs for treating insomnia are mainly benzodiazepines. Although the curative effect is good, they are prone to tolerance and long-term use will cause addiction.

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