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Medicine composition for curing infantile diarrhea

A technology of infantile diarrhea and composition, applied in the field of medicine, to achieve the effect of inhibiting small intestine propulsion, uniform and stable drug quality, and inhibiting diarrhea in mice

Inactive Publication Date: 2008-02-20
SHANDONG XUANZHU PHARMA TECH CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0007] At present, the use of sargassum, pomegranate peel and paojiang charcoal to interact and combine prescriptions to prepare a pharmaceutical composition for treating diarrhea in children has not been reported yet.

Method used

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  • Medicine composition for curing infantile diarrhea

Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0073] Embodiment 1: the preparation of pharmaceutical composition tablet of the present invention

[0074] Swollen knot wind 450g Pomegranate peel 450g Paojiang charcoal 360g

[0075] Take the sargassum, pomegranate peel and Paojiang charcoal of said parts by weight; decoct and extract the weighed sargassum, pomegranate peel and Paojiang charcoal twice, add 8 times of water for the first time, extract 3 hour, add 6 times the amount of water for the second time, extract for 2 hours, combine the water extracts, filter, concentrate the filtrate to a relative density of 1.15-1.18, add ethanol until the alcohol content is 70%, stir evenly, refrigerate and let stand for alcohol precipitation After 24 hours, filter, and recover ethanol from the filtrate under reduced pressure until there is no alcohol smell, continue to concentrate to a thick paste, dry, pulverize, add auxiliary materials to make granules, dry, and press into tablets.

Embodiment 2

[0076] Embodiment 2: the preparation of pharmaceutical composition capsule of the present invention

[0077] Swollen knot wind 400g Pomegranate peel 400g Paojiang charcoal 320g

[0078] Take the sargassum, pomegranate peel and Paojiang charcoal of said parts by weight; decoct and extract the weighed sargassum, pomegranate peel and Paojiang charcoal twice, add 8 times of water for the first time, extract 3 hour, add 6 times the amount of water for the second time, extract for 2 hours, combine the water extracts, filter, concentrate the filtrate to a relative density of 1.15-1.18, add ethanol until the alcohol content is 70%, stir evenly, refrigerate and let stand for alcohol precipitation After 24 hours, filter, and recover ethanol from the filtrate under reduced pressure until there is no alcohol smell, continue to concentrate to a thick paste, dry, pulverize, and pack into hard gelatin capsules.

Embodiment 3

[0079] Embodiment 3: the preparation of pharmaceutical composition granule of the present invention

[0080] Swollen knot wind 450g Pomegranate peel 450g Paojiang charcoal 360g

[0081] Take the sargassum, pomegranate peel and Paojiang charcoal of said parts by weight; decoct and extract the weighed sargassum, pomegranate peel and Paojiang charcoal twice, add 8 times of water for the first time, extract 3 hour, add 6 times the amount of water for the second time, extract for 2 hours, combine the water extracts, filter, concentrate the filtrate to a relative density of 1.15-1.18, add ethanol until the alcohol content is 70%, stir evenly, refrigerate and let stand for alcohol precipitation After 24 hours, filter, and recover ethanol from the filtrate under reduced pressure until there is no alcohol smell, continue to concentrate to a thick paste, dry, pulverize, add sugar powder and binder to make granules.

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Abstract

The present invention pertains to the field of pharmaceutical technology and discloses a pharmaceutical composition mainly for treating infantile diarrhea and the preparation method thereof. The pharmaceutical composition is mainly prepared by glabrous sarcandra herb, pomegranate rind and common ginger charcoal according to certain mix ratio by weight. The present invention can be made into any formulation which is acceptable clinically or on the pharmacy, while the oral preparation is preferential. The pharmaceutical composition has the effects of expelling toxin, astringing intestine, warming spleen and stopping diarrhea and can be used for infantile diarrhea and has special effect on the infantile diarrhea in autumn.

Description

1. Technical field [0001] The invention belongs to the technical field of medicines, and in particular relates to a pharmaceutical composition mainly used for infantile diarrhea, which is mainly made of sargassum, pomegranate peel and paojiang charcoal. 2. Background technology [0002] Diarrhea in children is a digestive tract syndrome that can occur throughout the year, but it is most frequent in summer and autumn. Autumn diarrhea is mainly caused by rotavirus, followed by calicivirus and astrovirus. The virus invades the villous epithelial cells of the small intestine, causing crypt and crypt cell dysfunction, causing secretory and malabsorptive diarrhea. It belongs to the category of exogenous diarrhea in traditional Chinese medicine. Traditional Chinese medicine believes that the origin of diarrhea lies in the spleen and stomach, the stomach is the sea of ​​water and valleys, which is mainly for receiving, and the spleen is the source of biochemistry, which is in char...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/9068A61P1/12
Inventor 黄振华
Owner SHANDONG XUANZHU PHARMA TECH CO LTD
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