43 results about "VASCULAR ABNORMALITY" patented technology

Embodiments of the present invention provide medical devices and methods for treating a target site within the body, such as for treating vascular abnormalities. For example, one embodiment provides a stent graft including an occlusive material having a preset, overlapping configuration comprising at least three inverted overlapping layers that are folded over one another. The at least three inverted overlapping layers are configured to be separated and disposed within a catheter in a non-overlapping configuration and return to the preset, overlapping configuration when deployed from the catheter.

A catheter deliverable stent / graft especially designed to be used in a minimally invasive surgical procedure for treating a variety of vascular conditions such as aneurysms, stenotic lesions and saphenous vein grafts, comprises an innermost tubular structure and at least one further tubular member in coaxial arrangement. In one embodiment, the innermost tubular structure is of a length (L 1 ) and is formed by braiding a relatively few strands of highly elastic metallic alloy. The pick and pitch of the braid are such as to provide relative large fenestrations in the tubular wall that permit blood flow through the wall and provide the primary radial support structure. A portion of the innermost tubular structure of a length (L 1 ) is surrounded by a further braided tubular structure having relatively many strands that substantially inhibit blood flow through the fenestrations of the innermost tubular structure.

A catheter deliverable stent / graft especially designed to be used in a minimally invasive surgical procedure for treating a variety of vascular conditions such as aneurysms, stenotic lesions and saphenous vein grafts, comprises an innermost tubular structure and at least one further tubular member in coaxial arrangement. In one embodiment, the innermost tubular structure is of a length (L1) and is formed by braiding a relatively few strands of highly elastic metallic alloy. The pick and pitch of the braid are such as to provide relative large fenestrations in the tubular wall that permit blood flow through the wall and provide the primary radial support structure. A portion of the innermost tubular structure of a length L1 is surrounded by a further braided tubular structure having relatively many strands that substantially inhibit blood flow through the fenestrations of the innermost tubular structure. The composite structure can be stretched to reduce the outer diameter of the stent / graft, allowing it to be drawn into a lumen of a delivery catheter. The catheter can then be advanced through the vascular system to the site of treatment and then released, allowing it to self-expand against the vessel wall. Various optional embodiments are disclosed that allow one skilled in the art to tailor the design to the specific application.

A beam of radiation can be provided to treat a dermatological condition in a target region of skin. The beam of radiation can have a wavelength between about 700 nm and about 800 nm, a fluence greater than about 50 J / cm2, and a pulse duration between about 10 msec and about 300 msec. The beam of radiation is delivered to the target region of skin to affect (i) at least one pigmentary abnormality disposed in an epidermal region of the target region and (ii) at least one vascular abnormality disposed in a dermal region of the target region. A surface of the epidermal region of the target region of skin can be cooled to prevent substantial unwanted injury to at least a portion of the epidermal region.

A method and apparatus for vascular disease detection and characterization using a recurrent neural network (RNN) is disclosed. A plurality of 2D cross-section image patches are extracted from a 3D computed tomography angiography (CTA) image, each extracted at a respective sampling point along a vessel centerline of a vessel of interest in the 3D CTA image. Vascular abnormalities in the vessel of interest are detected and characterized by classifying each of the sampling points along the vessel centerline based on the plurality of 2D cross-section image patches using a trained RNN.

A stent / stent graft for reinforcement of vascular abnormalities and an associated method are provided. According to on embodiment, the stent / stent graft includes a flexible tubular structure comprising proximal and distal ends and having a heat set configuration. The tubular structure is configured to engage a lumen upstream and downstream of a vascular abnormality, such as an aneurysm, and a portion between the proximal and distal ends of the tubular structure is configured to engage the aneurysm.

Embodiments of the present invention provide medical devices and methods for treating a target site within the body, such as for treating vascular abnormalities. For example, one embodiment provides an occlusion device including an occlusive material having proximal and distal ends and a central axis extending therebetween. The occlusive material has a preset, overlapping configuration including at least three inverted overlapping layers folded over one another, wherein the at least three inverted overlapping layers are aligned with the central axis within about 45 degrees or less and are configured to be separated and disposed within a catheter in a non-overlapping configuration and return to the preset, overlapping configuration when deployed from the catheter.

A vascular device is provided that includes a tubular structure and an occluding structure. The tubular structure has inner and outer layers, with the occluding structure located between the inner and outer layers. Each of the inner and outer layers may define a different pick count, and the tubular structure may include a leading edge at a transition between the pick counts. The leading edge may be disposed at the distal end of the vascular device when the device is deployed from a delivery device. Furthermore, the occluding structure may have first and second layers formed by the inversion or eversion of the occluding structure and the subsequent coupling of its free ends to form a continuous structure. Thus, any loose ends may be sealed to minimize unraveling and / or shifting of the occluding structure within the tubular structure. A method of making the vascular device is also provided.

Methods are provided for using a compound to treat, for example, endothelial dysfunction including vascular abnormalities. More specifically, methods are described for using an oligosaccharide compound or glycomimetic compound wherein a cyclohexane derivative is incorporated in either.

Embodiments of the present invention provide medical devices and methods for treating a target site within the body, such as for treating vascular abnormalities. For example, one embodiment provides medical device including a first tubular member that includes a first portion, a second portion, and a central portion disposed between the first portion and the second portion. Each of the first and second portions have a radius that is larger than that of the central portion, and the second portion has a preset, relaxed configuration in which a portion of the second portion has a partial discoid shape defined by an inversion of a portion of a discoid into itself.

Embodiments of the present invention provide medical devices and methods for treating a target site within the body, such as for treating vascular abnormalities. For example, one embodiment provides a stent graft including an occlusive material having a preset, overlapping configuration comprising at least three inverted overlapping layers that are folded over one another. The at least three inverted overlapping layers are configured to be separated and disposed within a catheter in a non-overlapping configuration and return to the preset, overlapping configuration when deployed from the catheter.