Combinations of chromium or vanadium with antidiabetics for glucose metabolism disorders
a technology of chromium vanadium and antidiabetic, which is applied in the direction of metabolism disorder, extracellular fluid disorder, peptide/protein ingredient, etc., can solve the problems of increasing the number of insulin deficiencies, reducing the effect of chromium vanadium, and affecting the way the body uses sugar, so as to prevent or delay the on-set of diabetes or diabetic symptoms, and preserving health
- Summary
- Abstract
- Description
- Claims
- Application Information
AI Technical Summary
Benefits of technology
Problems solved by technology
Method used
Examples
example one
[0231] A supplement (detailed below) was administered daily to a female with Type 2 diabetes who was experiencing poor blood sugar control while taking metformin 500 mg b.i.d. In conjunction with continued metformin administration, the patient was given an oral daily nutritional supplement comprising the following ingredients: chromium 333 mcg (in the form of chromium picolinate / polynicotinate); magnesium 46 mg (in the form of 384 mg magnesium chloride); vanadyl-sulfate hydrate 100 mg; vitamin E 400 I.U, and folate 400 mcg.
[0232] The results are summarized below in Table 1
TABLE 1HbA1cEstimated BloodFasting BloodTherapeutic RegimenLevelSugar (mg / dL)Sugar (mg / dL)Metformin alone9.7200185Metformin &7.9141153composition(after 2 months)
[0233] The above results indicate the degree to which a composition consisting of components and an anti-diabetic agent according to the present invention, administered in accordance with invention methods, may dramatically improve blood sugar control an...
example two
[0236] To further test the efficacy of inventive compositions, a certain embodiment of the present invention, the supplement detailed below, was administered daily to a 27 year old female with Type 2 diabetes who was experiencing poor blood sugar control while taking metformin 1000 mg b.i.d.
[0237] After 3 months of augmenting the daily regimen of 2000 mg metformin with the above oral nutritional supplement, the patient's HbA1c level dropped from 8.3 to 6.1. These results again serve to demonstrate the degree to which invention compositions, administered in accordance with invention methods, serves to beneficially lower a diabetic patient's HbA1c levels, even though the patient had experienced poor blood glucose control on high doses of metformin alone.
example three
[0238] In another example, a group of Type 2 diabetic individuals presenting with elevated HbA1c levels were placed on a program using a variety of embodiments of the present invention. The study was conducted as an open-label study at five different medical centers in the United States. The patients were on the program for three months, and were directed not to change their dietary habits or lifestyle, including exercise patterns.
[0239] For this Example Three, one daily dose of every embodiment contained, in addition to any of the anti-diabetic agents set forth in the accompanying tables, the following (component and amount):
[0240] Vitamin A, 5000 IU; Vitamin C (Ascorbic Acid), 60 mg; Vitamin D-3, 400 IU; Vitamin E (free 2R, 4′R, 8′R-alpha-tocopherol), 400 IU; Thiamine (as Thiamine Mononitrate), 3 mg; Riboflavin, 3.6 mg; Niacinamide, 20.1 mg; Vitamin B-6 (as Pyridoxine HCl), 23.1 mg; Folic Acid, 400 mcg; Vitamin B-12, 48 mcg; Biotin, 300 mcg; Pantothenic Acid (as Calcium Pantothe...
PUM
Property | Measurement | Unit |
---|---|---|
body weight | aaaaa | aaaaa |
body weight | aaaaa | aaaaa |
body weight | aaaaa | aaaaa |
Abstract
Description
Claims
Application Information
- R&D Engineer
- R&D Manager
- IP Professional
- Industry Leading Data Capabilities
- Powerful AI technology
- Patent DNA Extraction
Browse by: Latest US Patents, China's latest patents, Technical Efficacy Thesaurus, Application Domain, Technology Topic, Popular Technical Reports.
© 2024 PatSnap. All rights reserved.Legal|Privacy policy|Modern Slavery Act Transparency Statement|Sitemap|About US| Contact US: help@patsnap.com