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Plaster for treating diarrhea and its preparing method

A production method and technology of a production method, applied in the direction of non-active ingredient medical preparations, medical preparations containing active ingredients, pharmaceutical formulas, etc., can solve problems such as toxic side effects and patient safety issues, achieve less irritation, avoid Toxic side effects, no side effects

Inactive Publication Date: 2007-06-27
TIANJIN ZHONGBAO PHARMACY
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0002] Generally, when patients suffer from diarrhea, they are usually treated with medicaments, mostly oral medicines or injections, but both oral medicines and injections have toxic and side effects, and they will produce reactions through the first-pass effect of the liver and the release of the digestive tract. Patients pose safety concerns

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0021] Embodiment 1 (high dose)

[0022] The weight ratio is based on 1kg per serving:

[0023] Atractylodes macrocephala 10kg, Radix Paeoniae Alba 12kg, Chenpi 10kg, Fangfeng 10kg.

Embodiment 2

[0024] Embodiment 2 (low dosage)

[0025] The weight ratio is based on 1kg per serving:

[0026] Atractylodes macrocephala 5kg, Radix Paeoniae Alba 6kg, Chenpi 3kg, Fangfeng 5kg.

Embodiment 3

[0027] Embodiment 3 (medium dose)

[0028] The weight ratio is based on 1kg per serving:

[0029] Atractylodes macrocephala 7.5kg, Radix Paeoniae Alba 9kg, Chenpi 6.5kg, Fangfeng 7.5kg.

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PUM

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Abstract

The present invention is diarrhea treating plaster and its preparation. The diarrhea treating plaster is prepared with white atractylodes rhizome 5-10 weight portions, white peony root 6-12 weight portions, tangerine peel 3-10 weight portions and ledebouriella root 5-10 weight portions, and through material mixing, grinding to 100-200 micron size, supercritical CO2 extracting, fractioning in a fractioning tower, nanometer dispersing to form nanometer slurry, adding transdermal promoter and contact adhesive, coating in a low temperature rotary coating machine, cutting, inspection and packing. The present invention has extracted medicine filled in matrix skeleton, compatibility of the matrix to skin, slow medicine release, smooth acting, less stimulation and no toxic side effect.

Description

technical field [0001] The invention relates to a traditional Chinese medicine patch, in particular to a patch for treating diarrhea and a preparation method thereof. Background technique [0002] Generally, when patients suffer from diarrhea, they are usually treated with medicaments, mostly oral medicines or injections, but both oral medicines and injections have toxic and side effects, and they will produce reactions through the first-pass effect of the liver and the release of the digestive tract. Patients present safety concerns. Contents of the invention [0003] The main purpose of the present invention is to solve the toxic and side effects of oral medicines and injections on the human body, and provide a patch for treating diarrhea that avoids the toxic and side effects of oral administration and does not go through the first-pass effect of the liver and the dilution of the digestive tract. and production methods. [0004] The technical solution adopted by the p...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/752A61K9/70A61K47/42A61K47/40A61K47/38A61K47/32A61K47/02A61P1/12
Inventor 李建民
Owner TIANJIN ZHONGBAO PHARMACY
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