Drop pills prepared from andrographolide sulfonated compounds and preparation method thereof

Abstract

A dripping pill of the Chinese medicine Xiyanping for treating bronchitis, tonsillitis and bacterial dysentery and its preparing process are disclosed.

Description

technical field [0001] The present invention relates to a kind of medicinal composition that can clear heat and detoxify, relieve cough and dysentery, and is used for the treatment of bronchitis, tonsillitis, bacillary dysentery, etc. Oral drop pill preparation of a kind of pharmaceutical composition formed by drug route. Background technique [0002] According to the formula and extraction process given in the national drug standard WS-10862 (ZD-0863)-2002, Xiyanping injection is a kind of liquid with clearing away heat and detoxification; Injection preparations for the treatment of infections, bronchial pneumonia, viral pneumonia, suppurative diseases, gynecological inflammation and postoperative fever have been clinically verified for many years, with stable quality and definite curative effect. They are commonly used in clinics and families to treat the above diseases. Pharmaceutical preparations. [0003] The following are the formula and extraction process of Xiyanpi...

AI Technical Summary

Problems solved by technology

[0012] In addition, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking, which affect the quality of the drug. Efficacy, also directly affects the therapeutic effect Conventional oral dosage forms, such as tablets, capsules, etc.

In addition, due to the granulation process in the preparation process, large dust pollution will be generated, which will cause harm to the health of the staff to a certain extent, and will also cause certain pollution to the environment.

Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.