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Oral administration dripping pill for nourishing heart to calm mind and its preparing method

The technology of a spring dripping pill and a dripping pill machine is applied to the oral dripping pills with the effect of nourishing the heart and the nerves and the preparation field thereof, which can solve the problems of inconvenient taking or carrying, low dissolution rate, unfavorable overall health level and the like, and achieves the improvement of biological The availability, dissolution and absorption are accelerated, and the effect is beneficial to labor protection

Inactive Publication Date: 2007-01-03
北京博智绿洲医药科技有限公司
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

[0006] Due to the preparation technology and other reasons, the oral preparations of most drugs, especially the oral preparations of traditional Chinese medicine, have problems such as long dissolution time, low dissolution rate, poor absorption, hepatic and intestinal first-pass effect and low bioavailability after taking. , thus affecting the efficacy of the drug and directly affecting the therapeutic effect
However, syrup oral preparations also have disadvantages such as low drug content, difficulty in taking and measuring accurately, inconvenient taking or carrying, etc.
[0007] In addition, conventional oral dosage forms, such as tablets, capsules, etc., will produce relatively large dust pollution due to the granulation process in the preparation process, which will cause harm to the health of the staff to a certain extent, and will also cause harm to the human body. some pollution to the environment
Furthermore, the production process of conventional oral preparations is complicated and the production cost is high, so that the cost of medication for patients is also increased, which is not conducive to improving the ability of patients to seek medical treatment, and is also not conducive to improving the overall health level of society.

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment Construction

[0029] Now with several groups of specific examples, the preparation method of Kangfuchun dripping pills of the present invention will be further described.

[0030] Group 1: Tests with a single matrix

[0031] 1. Preparation of drug extract: Prepare according to [Appendix: A preparation method of drug extract] to obtain dry extract powder containing active ingredients of 4 traditional Chinese medicines, such as astragalus, ginseng, polygonatum, and royal jelly;

[0032] 2. Substrate: polyethylene glycol (2000、4000、6000、8000、10000、20000) , polyoxyl 40 stearate, beta cyclodextrin, poloxamer, sodium carboxymethyl starch, sodium lauryl sulfate, stearic acid, sodium stearate, glycerin gelatin, shellac, etc.;

[0033] 3. Proportion: take g or kg as the unit, by weight, drug extract: matrix = 1:1~1:9;

[0034] 4. According to the process given in [Preparation Method] 4-7, different specifications of Kangfuchun Dropping Pills can be obtained.

[0035] [test results]

[0036] Expe...

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PUM

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Abstract

The orally taken dripping pill has the functions of benefiting vital energy, consolidating superficial resistance, nourishing heart, tranquilizing, invigorating spleen, regulating the function of the stomach, and is used in treating heart and spleen deficiency, poor appetite, lacking in strength, insomnia, etc. The orally taken dripping pill is prepared with astragalus root, ginseng, fragrant solomonseal rhizome and royal jelly as main material as well as matrix carrier, and has high bioavailability, fast acting, high effective content, taking convenience and low cost.

Description

technical field [0001] The invention relates to a kind of medicine which has the functions of replenishing qi and strengthening the exterior, nourishing the heart and calming the nerves, invigorating the spleen and harmonizing the stomach, and is used for treating diseases such as deficiency of the heart and spleen, lack of food and mind, abdominal distension, fullness, lack of energy, palpitation and palpitation, mental fatigue, insomnia and other diseases. The pharmaceutical composition of the present invention particularly relates to a kind of oral preparation of a pharmaceutical composition prepared from 4 traditional Chinese medicines such as astragalus, ginseng, polygonatum odoratum, and royal jelly. Background technique [0002] According to the ministerial drug standard WS 3 - Kangfuchun Oral Liquid prepared by the preparation method given in B-3987-98 is a kind of food that has the functions of nourishing qi and strengthening the exterior, nourishing the heart and c...

Claims

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Application Information

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Patent Type & Authority Patents(China)
IPC IPC(8): A61K9/20A61K36/8969A61K36/481A61K36/258A61K35/64A61P1/14A61P25/20A61K125/00A61K35/644
Inventor 曲韵智
Owner 北京博智绿洲医药科技有限公司
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