Detection method of swelling and pain relieving vinegar paste

Abstract

The detection method comprises the following steps: carrying out thin-layer identification on a cortex phellodendri medicinal material, a pinellia ternate medicinal material, a lycopodium clavatum medicinal material, a gallnut medicinal material and berberine hydrochloride in the swelling and pain relieving vinegar paste. According to the detection method, thin-layer identification of a pinellia ternate medicinal material is added on the basis of an original detection method, a thin-layer identification method of a cortex phellodendri medicinal material is optimized, methodological investigation shows that the detection method has the effects of high specificity, good durability, clear spots after thin-layer expansion, satisfactory separation degree, moderate Rf value and the like, and the quality condition of a product can be effectively controlled; the product quality detection standard is improved, the product quality is ensured, and the harm of benzene to detection personnel and the environmental pollution can be reduced.

Description

technical field [0001] The invention relates to the field of drug detection, in particular to a detection method for Xiaozhutong vinegar ointment. Background technique [0002] Xiaozhutong vinegar ointment is the exclusive variety of Guizhou Liangji Pharmaceutical Co., Ltd. It was approved by the State Food and Drug Administration in 2006 (Z20064278). ), Tendon grass, the preparation method is to take the above four medicinal materials and pulverize them into fine powder, sieve, mix, and prepare by adding rice vinegar. For closed soft tissue injury, herpes zoster, mumps, thrombophlebitis, etc. [0003] The current standard of Xiaozhutong vinegar ointment is the drug standard of the State Food and Drug Administration (standard number: WS 3 -B-1214-92-2014), the current standard detection method only contains the microscopic identification of Xiaozhutong vinegar paste, the thin layer identification of E. , but the following defects exist in the actual detection: (1) the mic...

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Problems solved by technology

[0003] The current standard of Xiaozhongtong vinegar ointment is the drug standard of the State Food and Drug Administration (standard number: WS 3 -B-1214-92-2014), the current standard detection method only includes the microscopic identification of Xiaozhongtong vinegar ointment, the TLC identification of Shenjincao, Galla gallinaceus, Phellodendron Phellodendri, the content determination of berberine hydrochloride and related inspection items , but there are the following defects in the actual detection: (1) the microscopic features in the microscopic identification of Xiaozhongtong vinegar ointment are not obvious, the reproducibility is poor, the result is not easy to judge, and the detection resources are wasted; (2) the thin-layer identification of Cortex Phellodendri In the TLC spectrum, the Rf value of the spot is less than 0.2, and the spot tailing of the control medicinal material and the reference substance is serious; (3) The chemical reagent benzene contained in the developer is highly toxic and can enter the human body through the skin and respiratory tract, and is extremely difficult to degrade in the body. It is beneficial to the health of testing personnel and environmental protection; (3) the detection method does not involve the thin-layer identification of Pinellia medicinal materials in prescriptions, and cannot effectively and comprehensively control the quality of Xiaozhongtong vinegar ointment

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